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Multiplexed immunofluorescence microscopy captures detailed measurements of spatially resolved, multiple biomarkers simultaneously, revealing tissue composition and cellular interactions in situ among single cells. The growing scale and…

Software Engineering · Computer Science 2025-06-03 Fang Liu , Rui He , Andrei Bombin , Ahmad B. Abdallah , Omar Eldaghar , Tommy R. Sheeley , Sam E. Ying , George Zaki

An efficient hardware implementation for Simultaneous Localization and Mapping (SLAM) methods is of necessity for mobile autonomous robots with limited computational resources. In this paper, we propose a resource-efficient FPGA…

Signal Processing · Electrical Eng. & Systems 2023-05-31 Keisuke Sugiura , Hiroki Matsutani

This work proposes a two-step method to enhance disease risk estimation in small areas by integrating spatiotemporal cluster detection within a Bayesian hierarchical spatiotemporal model. First, we introduce an efficient…

Methodology · Statistics 2026-04-14 G. Santafé , A. Adin , M. D. Ugarte

We present an algorithm for cluster dynamics to efficiently simulate large systems on MIMD parallel computers with large numbers of processors. The method divides physical space into rectangular cells which are assigned to processors and…

High Energy Physics - Lattice · Physics 2009-10-22 Mike Flanigan , Pablo Tamayo

The use of brain images as markers for diseases or behavioral differences is challenged by the small effects size and the ensuing lack of power, an issue that has incited researchers to rely more systematically on large cohorts. Coupled…

Machine Learning · Statistics 2015-11-17 Bertrand Thirion , Andrés Hoyos-Idrobo , Jonas Kahn , Gael Varoquaux

The purpose of the research is to determine if currently available self-supervised learning techniques can accomplish human level comprehension of visual images using the same degree and amount of sensory input that people acquire from.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Prateek Y J

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Background. Digital pathology has aroused widespread interest in modern pathology. The key of digitalization is to scan the whole slide image (WSI) at high magnification. The lager the magnification is, the richer details WSI will provide,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Kai Sun , Yanhua Gao , Ting Xie , Xun Wang , Qingqing Yang , Le Chen , Kuansong Wang , Gang Yu

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Jiusong Ge , Yingkang Zhan , Wenjie Zhao , Di Zhang , Ke Wang , Jiashuai Liu , Chunze Yang , Chengzu Li , Jian Zhang , Yuxin Dong , Ni Zhang , Qidong Liu , Mireia Crispin-Ortuzar , Huazhu Fu , Chen Li , Zeyu Gao

w-Projection is a wide-field imaging technique that is widely used in radio synthesis arrays. Processing the wide-field big data generated by the future Square Kilometre Array (SKA) will require significant updates to current methods to…

Instrumentation and Methods for Astrophysics · Physics 2019-11-11 Baoqiang Lao , Tao An , Ang Yu , Wenhui Zhang , Junyi Wang , Quan Guo , Shaoguang Guo , Xiaocong Wu

In several application domains, high-dimensional observations are collected and then analysed in search for naturally occurring data clusters which might provide further insights about the nature of the problem. In this paper we describe a…

Machine Learning · Statistics 2012-03-07 Brian McWilliams , Giovanni Montana

Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate approaches that lead to information waste.…

Methodology · Statistics 2025-11-18 Yuan Zhong , Gang Chen , Paul A. Taylor , Jian Kang

Multiple signal classification algorithm (MUSICAL) provides a super-resolution microscopy method. In the previous research, MUSICAL has enabled data-parallelism well on a desktop computer or a Linux-based server. However, the running time…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-14 Quan Do , Jon Ivar Kristiansen , Krishna Agarwal , Phuong Hoai Ha

Analyzing gigapixel images is recognized as computationally demanding. In this paper, we introduce PyramidAI, a technique for analyzing gigapixel images with reduced computational cost. The proposed approach adopts a gradual analysis of the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Marie Reinbigler , Rishi Sharma , Rafael Pires , Elisabeth Brunet , Anne-Marie Kermarrec , Catalin Fetita

Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extraction pipelines based on tools like CellProfiler often involve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Yuechen Yang , Yu Wang , Tianyuan Yao , Ruining Deng , Mengmeng Yin , Shilin Zhao , Haichun Yang , Yuankai Huo

Scatterplots provide a visual representation of bivariate data (or 2D embeddings of multivariate data) that allows for effective analyses of data dependencies, clusters, trends, and outliers. Unfortunately, classical scatterplots suffer…

Human-Computer Interaction · Computer Science 2026-04-16 Hennes Rave , Vladimir Molchanov , Lars Linsen

Ultra-High-Definition (UHD) image restoration is trapped in a scalability crisis: existing models, bound to pixel-wise operations, demand unsustainable computation. While state space models (SSMs) like Mamba promise linear complexity, their…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Chen Wu , Ling Wang , Zhuoran Zheng , Yuning Cui , Zhixiong Yang , Xiangyu Chen , Yue Zhang , Weidong Jiang , Jingyuan Xia

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

Computational Complexity · Computer Science 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Efficiently modeling large 2D contexts is essential for various fields including Giga-Pixel Whole Slide Imaging (WSI) and remote sensing. Transformer-based models offer high parallelism but face challenges due to their quadratic complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Jingwei Zhang , Anh Tien Nguyen , Xi Han , Vincent Quoc-Huy Trinh , Hong Qin , Dimitris Samaras , Mahdi S. Hosseini

Measuring the perceptual quality of images automatically is an essential task in the area of computer vision, as degradations on image quality can exist in many processes from image acquisition, transmission to enhancing. Many Image Quality…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Jing Wang , Haotian Fan , Xiaoxia Hou , Yitian Xu , Tao Li , Xuechao Lu , Lean Fu