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Animals (especially humans) have an amazing ability to learn new tasks quickly, and switch between them flexibly. How brains support this ability is largely unknown, both neuroscientifically and algorithmically. One reasonable supposition…

Machine Learning · Computer Science 2017-06-23 Kevin T. Feigelis , Daniel L. K. Yamins

In the mammalian brain, newly acquired memories depend on the hippocampus for maintenance and recall, but over time the neocortex takes over these functions, rendering memories hippocampus-independent. The process responsible for this…

Neurons and Cognition · Quantitative Biology 2021-07-02 Peter Helfer , Thomas R. Shultz

Learning weights in a spiking neural network with hidden neurons, using local, stable and online rules, to control non-linear body dynamics is an open problem. Here, we employ a supervised scheme, Feedback-based Online Local Learning Of…

Neurons and Cognition · Quantitative Biology 2019-02-19 Aditya Gilra , Wulfram Gerstner

Running is a fundamental form of human locomotion and a key task for evaluating neuromuscular control and lower-limb coordination. In recent years, muscle synergy analysis based on surface electromyography (sEMG) has become an important…

Quantitative Methods · Quantitative Biology 2026-01-01 Ye Ma , Shixin Lin , Shengxing Fu , Yuwei Liu , Chenyi Guo , Dongwei Liu , Meijin Hou

Robots will become ubiquitously useful only when they can use few attempts to teach themselves to perform different tasks, even with complex bodies and in dynamical environments. Vertebrates, in fact, successfully use trial-and-error to…

Balance control is important for human and bipedal robotic systems. While dynamic balance during locomotion has received considerable attention, quantitative understanding of static balance and falling remains limited. This work presents a…

Robotics · Computer Science 2025-09-09 Chengtian Ma , Yunyue Wei , Chenhui Zuo , Chen Zhang , Yanan Sui

Plans for a new type of artificial brain are possible because of realistic neurons in logically structured arrays of controlled toggles, one toggle per neuron. Controlled toggles can be made to compute, in parallel, parameters of critical…

Emerging Technologies · Computer Science 2015-04-20 John Robert Burger

The brain has evolved to effectively control the body, and in order to understand the relationship we need to model the sensorimotor transformations underlying embodied control. As part of a coordinated effort, we are developing a…

Machine Learning · Computer Science 2025-12-01 Eric Leonardis , Akira Nagamori , Ayesha Thanawalla , Yuanjia Yang , Joshua Park , Hutton Saunders , Eiman Azim , Talmo Pereira

Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…

Neurons and Cognition · Quantitative Biology 2019-06-20 Giancarlo La Camera , Alfredo Fontanini , Luca Mazzucato

Human body motions can be captured as a high-dimensional continuous signal using motion sensor technologies. The resulting data can be surprisingly rich in information, even when captured from persons with limited mobility. In this work, we…

Locomotion has seen dramatic progress for walking or running across challenging terrains. However, robotic quadrupeds are still far behind their biological counterparts, such as dogs, which display a variety of agile skills and can use the…

Robotics · Computer Science 2023-03-23 Xuxin Cheng , Ashish Kumar , Deepak Pathak

The characterization of coordinated activity in neuronal populations has received renewed interest in the light of advancing experimental techniques which allow recordings from multiple units simultaneously. Across both in vitro and in vivo…

Neurons and Cognition · Quantitative Biology 2015-06-16 Feraz Azhar , William S. Anderson

Robots that can operate autonomously in a human living environment are necessary to have the ability to handle various tasks flexibly. One crucial element is coordinated bimanual movements that enable functions that are difficult to perform…

Robotics · Computer Science 2025-03-19 Tomohiro Motoda , Ryo Hanai , Ryoichi Nakajo , Masaki Murooka , Floris Erich , Yukiyasu Domae

We address the problem of stability of motor actions implemented by the central nervous system based on simple algorithms potentially reflecting physical (including physiological) processes within the body. A number of conceptually simple…

Neurons and Cognition · Quantitative Biology 2015-06-24 V. M. Akulin , F. Carlier , Stanislaw Solnik , M. L. Latash

Many day-to-day activities involve people working collaboratively toward reaching a desired outcome. Previous research in motor control and neuroscience have proposed inter-personal motor synergy (IPMS) as a mechanism of collaboration…

Systems and Control · Electrical Eng. & Systems 2021-10-22 Sara Honarvar , Jin-OH Hahn , Tim Kiemel , Jae Kun Shim , Yancy Diaz-Mercado

This manuscript presents control of a high-DOF fully actuated lower-limb exoskeleton for paraplegic individuals. The key novelty is the ability for the user to walk without the use of crutches or other external means of stabilization. We…

Learning effective continuous control policies in high-dimensional systems, including musculoskeletal agents, remains a significant challenge. Over the course of biological evolution, organisms have developed robust mechanisms for…

Robotics · Computer Science 2023-07-17 Cameron Berg , Vittorio Caggiano , Vikash Kumar

When facing a task of balancing a dynamic system near an unstable equilibrium, humans often adopt intermittent control strategy: instead of continuously controlling the system, they repeatedly switch the control on and off. Paradigmatic…

Biological Physics · Physics 2015-03-27 Arkady Zgonnikov , Ihor Lubashevsky

Humans excel at robust bipedal walking in complex natural environments. In each step, they adequately tune the interaction of biomechanical muscle dynamics and neuronal signals to be robust against uncertainties in ground conditions.…

It is doubtful that animals have perfect inverse models of their limbs (e.g., what muscle contraction must be applied to every joint to reach a particular location in space). However, in robot control, moving an arm's end-effector to a…

Robotics · Computer Science 2022-09-19 Justus Huebotter , Serge Thill , Marcel van Gerven , Pablo Lanillos
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