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Deformable image registration (DIR) remains a fundamental yet challenging problem in medical image analysis, largely due to the prohibitively high-dimensional deformation space of dense displacement fields and the scarcity of voxel-level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Runxun Zhang , Yizhou Liu , Li Dongrui , Bo XU , Jingwei Wei

As neural networks are increasingly deployed in dynamic environments, they face the challenge of catastrophic forgetting, the tendency to overwrite previously learned knowledge when adapting to new tasks, resulting in severe performance…

Machine Learning · Computer Science 2026-03-31 Anika Singh , Aayush Dhaulakhandi , Varun Chopade , Likhith Malipati , David Martinez , Kevin Zhu

Few-shot meta-learning presents a challenge for gradient descent optimization due to the limited number of training samples per task. To address this issue, we propose an episodic memory optimization for meta-learning, we call EMO, which is…

Machine Learning · Computer Science 2023-06-28 Yingjun Du , Jiayi Shen , Xiantong Zhen , Cees G. M. Snoek

Deep learning-based methods have recently demonstrated promising results in deformable image registration for a wide range of medical image analysis tasks. However, existing deep learning-based methods are usually limited to small…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Tony C. W. Mok , Albert C. S. Chung

Image registration is a process of aligning two or more images of same objects using geometric transformation. Most of the existing approaches work on the assumption of location invariance. These approaches require object-centric images to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Deepak Mishra , Rajeev Ranjan , Santanu Chaudhury , Mukul Sarkar , Arvinder Singh Soin

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

Deep learning-based deformable registration methods have been widely investigated in diverse medical applications. Learning-based deformable registration relies on weighted objective functions trading off registration accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Haoran Dou , Ning Bi , Luyi Han , Yuhao Huang , Ritse Mann , Xin Yang , Dong Ni , Nishant Ravikumar , Alejandro F. Frangi , Yunzhi Huang

In modern decentralized applications, ensuring communication efficiency and privacy for the users are the key challenges. In order to train machine-learning models, the algorithm has to communicate to the data center and sample data for its…

Optimization and Control · Mathematics 2024-04-04 Hoang Huy Nguyen , Yan Li , Tuo Zhao

Distributionally robust optimization (DRO) problems are increasingly seen as a viable method to train machine learning models for improved model generalization. These min-max formulations, however, are more difficult to solve. We therefore…

Machine Learning · Statistics 2020-11-03 Soumyadip Ghosh , Mark Squillante , Ebisa Wollega

Gradient-based meta-learning techniques are both widely applicable and proficient at solving challenging few-shot learning and fast adaptation problems. However, they have practical difficulties when operating on high-dimensional parameter…

Machine Learning · Computer Science 2019-03-27 Andrei A. Rusu , Dushyant Rao , Jakub Sygnowski , Oriol Vinyals , Razvan Pascanu , Simon Osindero , Raia Hadsell

We propose regularization schemes for deformable registration and efficient algorithms for their numerical approximation. We treat image registration as a variational optimal control problem. The deformation map is parametrized by its…

Optimization and Control · Mathematics 2016-09-09 Andreas Mang , George Biros

We present a performance analysis for image registration with gradient descent methods. We consider a typical multiscale registration setting where the global 2-D translation between a pair of images is estimated by smoothing the images and…

Computer Vision and Pattern Recognition · Computer Science 2014-01-14 Elif Vural , Pascal Frossard

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

Modern medical image registration approaches predict deformations using deep networks. These approaches achieve state-of-the-art (SOTA) registration accuracy and are generally fast. However, deep learning (DL) approaches are, in contrast to…

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Inverse optimization (IO) aims to determine optimization model parameters from observed decisions. However, IO is not part of a data scientist's toolkit in practice, especially as many general-purpose machine learning packages are widely…

Optimization and Control · Mathematics 2021-02-23 Elaheh H. Iraj , Daria Terekhov

Training Single-Image Super-Resolution (SISR) models using pixel-based regression losses can achieve high distortion metrics scores (e.g., PSNR and SSIM), but often results in blurry images due to insufficient recovery of high-frequency…

Image and Video Processing · Electrical Eng. & Systems 2024-09-10 Qiwen Zhu , Yanjie Wang , Shilv Cai , Liqun Chen , Jiahuan Zhou , Luxin Yan , Sheng Zhong , Xu Zou

Image registration with deep neural networks has become an active field of research and exciting avenue for a long standing problem in medical imaging. The goal is to learn a complex function that maps the appearance of input image pairs to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Matthew C. H. Lee , Ozan Oktay , Andreas Schuh , Michiel Schaap , Ben Glocker

Deformable image registration is a very important field of research in medical imaging. Recently multiple deep learning approaches were published in this area showing promising results. However, drawbacks of deep learning methods are the…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Tobias Fechter , Dimos Baltas

Recently, the Deep Learning community has become interested in evolutionary optimization (EO) as a means to address hard optimization problems, e.g. meta-learning through long inner loop unrolls or optimizing non-differentiable operators.…

Neural and Evolutionary Computing · Computer Science 2023-11-07 Robert Tjarko Lange , Yujin Tang , Yingtao Tian