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Related papers: Topology-Aware Exploration of Circle of Willis for…

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The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain. Its vascular architecture is believed to affect the risk, severity, and clinical outcome of serious neurovascular diseases. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Kaiyuan Yang , Fabio Musio , Yihui Ma , Norman Juchler , Johannes C. Paetzold , Rami Al-Maskari , Luciano Höher , Hongwei Bran Li , Ibrahim Ethem Hamamci , Anjany Sekuboyina , Suprosanna Shit , Houjing Huang , Chinmay Prabhakar , Ezequiel de la Rosa , Bastian Wittmann , Diana Waldmannstetter , Florian Kofler , Fernando Navarro , Martin Menten , Ivan Ezhov , Daniel Rueckert , Iris N. Vos , Ynte M. Ruigrok , Birgitta K. Velthuis , Hugo J. Kuijf , Pengcheng Shi , Wei Liu , Ting Ma , Maximilian R. Rokuss , Yannick Kirchhoff , Fabian Isensee , Klaus Maier-Hein , Chengcheng Zhu , Huilin Zhao , Philippe Bijlenga , Julien Hämmerli , Catherine Wurster , Laura Westphal , Jeroen Bisschop , Elisa Colombo , Hakim Baazaoui , Hannah-Lea Handelsmann , Andrew Makmur , James Hallinan , Amrish Soundararajan , Bene Wiestler , Jan S. Kirschke , Roland Wiest , Emmanuel Montagnon , Laurent Letourneau-Guillon , Kwanseok Oh , Dahye Lee , Adam Hilbert , Orhun Utku Aydin , Dimitrios Rallios , Jana Rieger , Satoru Tanioka , Alexander Koch , Dietmar Frey , Abdul Qayyum , Moona Mazher , Steven Niederer , Nico Disch , Julius Holzschuh , Dominic LaBella , Francesco Galati , Daniele Falcetta , Maria A. Zuluaga , Chaolong Lin , Haoran Zhao , Zehan Zhang , Minghui Zhang , Xin You , Hanxiao Zhang , Guang-Zhong Yang , Yun Gu , Sinyoung Ra , Jongyun Hwang , Hyunjin Park , Junqiang Chen , Marek Wodzinski , Henning Müller , Nesrin Mansouri , Florent Autrusseau , Cansu Yalçin , Rachika E. Hamadache , Clara Lisazo , Joaquim Salvi , Adrià Casamitjana , Xavier Lladó , Uma Maria Lal-Trehan Estrada , Valeriia Abramova , Luca Giancardo , Arnau Oliver , Paula Casademunt , Adrian Galdran , Matteo Delucchi , Jialu Liu , Haibin Huang , Yue Cui , Zehang Lin , Yusheng Liu , Shunzhi Zhu , Tatsat R. Patel , Adnan H. Siddiqui , Vincent M. Tutino , Maysam Orouskhani , Huayu Wang , Mahmud Mossa-Basha , Yuki Sato , Sven Hirsch , Susanne Wegener , Bjoern Menze

The Circle of Willis (CoW) is a critical network of arteries in the brain, often implicated in cerebrovascular pathologies. Voxel-level segmentation is an important first step toward an automated CoW assessment, but a full quantitative…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fabio Musio , Norman Juchler , Kaiyuan Yang , Suprosanna Shit , Chinmay Prabhakar , Bjoern Menze , Sven Hirsch

The Circle of Willis (CoW), vital for ensuring consistent blood flow to the brain, is closely linked to ischemic stroke. Accurate assessment of the CoW is important for identifying individuals at risk and guiding appropriate clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-12-04 Wenxuan Zhang , Shuai Li , Xinyi Wang , Yu Sun , Hongyu Kang , Pui Yuk Chryste Wan , Jing Qin , Yuanpeng Zhang , Yong-Ping Zheng , Sai-Kit Lam

Accurate multiclass segmentation of the Circle of Willis (CoW) is essential for neurovascular disease management but remains challenging due to complex vascular topology and variable morphology. Existing deep learning methods often suffer…

Machine Learning · Computer Science 2026-05-01 Jialu Liu , Yue Cui , Shan Yu

Magnetic resonance angiography (MRA) is an imaging modality for visualising blood vessels. It is useful for several diagnostic applications and for assessing the risk of adverse events such as haemorrhagic stroke (resulting from the rupture…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Yash Deo , Rodrigo Bonazzola , Haoran Dou , Yan Xia , Tianyou Wei , Nishant Ravikumar , Alejandro F. Frangi , Toni Lassila

Intracranial aneurysms (ICA) commonly occur in specific segments of the Circle of Willis (CoW), primarily, onto thirteen major arterial bifurcations. An accurate detection of these critical landmarks is necessary for a prompt and efficient…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 Rafic Nader , Vincent L'Allinec , Romain Bourcier , Florent Autrusseau

Most of the intracranial aneurysms (ICA) occur on a specific portion of the cerebral vascular tree named the Circle of Willis (CoW). More particularly, they mainly arise onto fifteen of the major arterial bifurcations constituting this…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Rafic Nader , Romain Bourcier , Florent Autrusseau

Cerebral hemodynamics is fundamentally regulated by the Circle of Willis (CoW), which redistributes flow through communicating arteries to stabilize perfusion under anatomical variations and vascular stenosis. In this study, we develop a…

Medical Physics · Physics 2025-12-22 Jiawei Liu , Atsushi Kanoke , Hidenori Endo , Kuniyasu Niizuma , Hiroshi Suito

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree: the cerebral arteries, the bifurcations and the intracranial aneurysms. By building this model, our goal was to provide a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

Intracranial aneurysm rupture causes subarachnoid hemorrhage with mortality near 50%, making early detection critical. Although CTA enables rapid screening, detecting small aneurysms within the complex three-dimensional branching of the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Antara Titikhsha , Divyanshu Tak

Topology is critical in tubular structures such as blood vessels, nerve fibers, and road networks, where connectivity and loop structure govern downstream functional analysis. Vision-Language Models (VLMs) are promising candidates for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Meilong Xu , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Xin Yu , Weimin Lyu , Kehan Qi , Dimitris Samaras , Chao Chen

During the diagnosis of ischemic strokes, the Circle of Willis and its surrounding vessels are the arteries of interest. Their visualization in case of an acute stroke is often enabled by Computed Tomography Angiography (CTA). Still, the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Florian Thamm , Markus Jürgens , Oliver Taubmann , Aleksandra Thamm , Leonhard Rist , Hendrik Ditt , Andreas Maier

Cerebrovascular disease often requires multiple imaging modalities for accurate diagnosis, treatment, and monitoring. Computed Tomography Angiography (CTA) and Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) are two common…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Alexander Koch , Orhun Utku Aydin , Adam Hilbert , Jana Rieger , Satoru Tanioka , Fujimaro Ishida , Dietmar Frey

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

The cerebrovascular tree is a complex anatomical structure that plays a crucial role in the brain irrigation. A precise identification of the bifurcations in the vascular network is essential for understanding various cerebral pathologies.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Ibtissam Essadik , Anass Nouri , Raja Touahni , Florent Autrusseau

Advances in imaging techniques enable high resolution 3D visualisation of vascular networks over time and reveal abnormal structural features such as twists and loops, and their quantification is an active area of research. Here we showcase…

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

Angular measurements are often modeled as circular random variables, where there are natural circular analogues of moments, including correlation. Because a product of circles is a torus, a d-dimensional vector of circular random variables…

Methodology · Statistics 2019-10-25 Natalie Klein , Josue Orellana , Scott Brincat , Earl K. Miller , Robert E. Kass

Time-of-flight magnetic resonance angiography (TOF-MRA) is one of the most widely used non-contrast MR imaging methods to visualize blood vessels, but due to the 3-D volume acquisition highly accelerated acquisition is necessary.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-05 Hyungjin Chung , Eunju Cha , Leonard Sunwoo , Jong Chul Ye
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