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A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for…

The process of fertilizing a human egg outside the body in order to help those suffering from infertility to conceive is known as in vitro fertilization (IVF). Despite being the most effective method of assisted reproductive technology…

Infertility, a pressing global health concern, affects a substantial proportion of individuals worldwide. While advancements in assisted reproductive technology (ART) have offered effective interventions, conventional in vitro…

Artificial Intelligence · Computer Science 2025-09-25 Xueqiang Ouyang , Jia Wei

Videomicroscopy is a promising tool combined with machine learning for studying the early development of in vitro fertilized bovine embryos and assessing its transferability as soon as possible. We aim to predict the embryo transferability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Yasmine Hachani , Patrick Bouthemy , Elisa Fromont , Sylvie Ruffini , Ludivine Laffont , Alline de Paula Reis

Time-lapse is a technology used to record the development of embryos during in-vitro fertilization (IVF). Accurate classification of embryo early development stages can provide embryologists valuable information for assessing the embryo…

Image and Video Processing · Electrical Eng. & Systems 2019-08-27 Zihan Liu , Bo Huang , Yuqi Cui , Yifan Xu , Bo Zhang , Lixia Zhu , Yang Wang , Lei Jin , Dongrui Wu

In vitro fertilization (IVF) comprises a sequence of interventions concerned with the creation and culture of embryos which are then transferred to the patient's uterus. While the clinically important endpoint is birth, the responses to…

Applications · Statistics 2020-10-21 Jack Wilkinson , Stephen A Roberts , Andy Vail

Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary…

Automating embryo viability prediction for in vitro fertilization (IVF) is important but challenging due to the limited availability of labeled pregnancy outcome data, as only a small fraction of embryos are labeled after transfer.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Zhiyi Shi , Junsik Kim , Helen Y. Yang , Yonghyun Song , Hyun-Jic Oh , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

Temporal embryo images and parental fertility table indicators are both valuable for pregnancy prediction in \textbf{in vitro fertilization embryo transfer} (IVF-ET). However, current machine learning models cannot make full use of the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Xueqiang Ouyang , Jia Wei , Wenjie Huo , Xiaocong Wang , Rui Li , Jianlong Zhou

The selection of the optimal embryo for transfer is a critical yet challenging step in in vitro fertilization (IVF), primarily due to its reliance on the manual inspection of extensive time-lapse imaging data. A key obstacle in this process…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Zahra Asghari Varzaneh , Niclas Wölner-Hanssen , Reza Khoshkangini , Thomas Ebner , Magnus Johnsson

In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis…

The timing of cell divisions in early embryos during the In-Vitro Fertilization (IVF) process is a key predictor of embryo viability. However, observing cell divisions in Time-Lapse Monitoring (TLM) is a time-consuming process and highly…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Tien-Phat Nguyen , Trong-Thang Pham , Tri Nguyen , Hieu Le , Dung Nguyen , Hau Lam , Phong Nguyen , Jennifer Fowler , Minh-Triet Tran , Ngan Le

To optimize clinical outcomes, fertility clinics must strategically select which embryos to transfer. Common selection heuristics are formulas expressed in terms of the durations required to reach various developmental milestones,…

Computer Vision and Pattern Recognition · Computer Science 2019-04-10 Tingfung Lau , Nathan Ng , Julian Gingold , Nina Desai , Julian McAuley , Zachary C. Lipton

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Ali Akbar Septiandri , Ade Jamal , Pritta Ameilia Iffanolida , Oki Riayati , Budi Wiweko

The application of artificial intelligence (AI) in IVF has shown promise in improving consistency and standardization of decisions, but often relies on annotated data and does not make use of the multimodal nature of IVF data. We…

Artificial Intelligence · Computer Science 2026-04-24 Nicklas Neu , Thomas Ebner , Jasmin Primus , Raphael Zefferer , Bernhard Schenkenfelder , Mathias Brunbauer , Florian Kromp

In vitro fertilization (IVF) is a widely utilized assisted reproductive technology, yet predicting its success remains challenging due to the multifaceted interplay of clinical, demographic, and procedural factors. This study develops a…

Embryo selection is one of multiple crucial steps in in-vitro fertilization, commonly based on morphological assessment by clinical embryologists. Although artificial intelligence methods have demonstrated their potential to support embryo…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nicklas Neu , Thomas Ebner , Jasmin Primus , Bernhard Schenkenfelder , Raphael Zefferer , Mathias Brunbauer , Florian Kromp

Reliable evaluation of blastocyst quality is critical for the success of in vitro fertilization (IVF) treatments. Current embryo grading practices primarily rely on visual assessment of morphological features, which introduces subjectivity,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Nahid Khoshk Angabini , Mohsen Tajgardan , Mahesh Madhavan , Zahra Asghari Varzaneh , Reza Khoshkangini , Thomas Ebner

Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The…

Quantitative Methods · Quantitative Biology 2019-11-12 Bo Zhang , Yuqi Cui , Meng Wang , Jingjing Li , Lei Jin , Dongrui Wu
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