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Self-adaptation solutions need to periodically monitor, reason about, and adapt a running system. The adaptation step involves generating an adaptation strategy and applying it to the running system whenever an anomaly arises. In this…

Software Engineering · Computer Science 2023-08-16 Jia Li , Shiva Nejati , Mehrdad Sabetzadeh

Software systems continuously evolve due to new functionalities, requirements, or maintenance activities. In the context of software evolution, software refactoring has gained a strategic relevance. The space of possible software…

Software Engineering · Computer Science 2024-01-31 Vittorio Cortellessa , Daniele Di Pompeo , Michele Tucci

Reversible Cellular Automata (RCA) are a particular kind of shift-invariant transformations characterized by a dynamics composed only of disjoint cycles. They have many applications in the simulation of physical systems, cryptography and…

Neural and Evolutionary Computing · Computer Science 2021-05-26 Luca Mariot , Stjepan Picek , Domagoj Jakobovic , Alberto Leporati

Gene Set Enrichment Analysis (GSEA) and its variations aim to discover collections of genes that show moderate but coordinated differences in expression. However, such techniques may be ineffective if many individual genes in a…

Genomics · Quantitative Biology 2011-01-19 Gang Fang , Michael Steinbach , Chad L. Myers , Vipin Kumar

Changepoint detection identifies significant shifts in data sequences, making it important in areas like finance, genetics, and healthcare. The Optimal Partitioning algorithms efficiently detect these changes, using a penalty parameter to…

Machine Learning · Computer Science 2025-10-07 Tung L Nguyen , Toby Hocking

Crossover designs are widely applied in medicine, agriculture, and other biological sciences, yet their analysis remains challenging due to longitudinal observations within each unit and the presence of carry-over effects. Despite their…

Computation · Statistics 2025-12-18 N. A. Cruz , O. O. Melo , C. A. Martinez , R. Alberich

In general, we can not use algebraic or enumerative methods to optimize a quality control (QC) procedure so as to detect the critical random and systematic analytical errors with stated probabilities, while the probability for false…

Neural and Evolutionary Computing · Computer Science 2018-12-03 Aristides T. Hatjimihail , Theophanes T. Hatjimihail

Change point estimation in its offline version is traditionally performed by optimizing over the data set of interest, by considering each data point as the true location parameter and computing a data fit criterion. Subsequently, the data…

Methodology · Statistics 2020-04-10 Zhiyuan Lu , Moulinath Banerjee , George Michailidis

Change-point analysis is thriving in this big data era to address problems arising in many fields where massive data sequences are collected to study complicated phenomena over time. It plays an important role in processing these data by…

Methodology · Statistics 2022-03-23 Yi-Wei Liu , Hao Chen

Change point estimation is often formulated as a search for the maximum of a gain function describing improved fits when segmenting the data. Searching through all candidates requires $O(n)$ evaluations of the gain function for an interval…

Methodology · Statistics 2024-11-22 Solt Kovács , Housen Li , Lorenz Haubner , Axel Munk , Peter Bühlmann

Diversity represents an important aspect of genetic programming, being directly correlated with search performance. When considered at the genotype level, diversity often requires expensive tree distance measures which have a negative…

Neural and Evolutionary Computing · Computer Science 2020-04-21 Bogdan Burlacu , Michael Affenzeller , Gabriel Kronberger , Michael Kommenda

With neural networks having demonstrated their versatility and benefits, the need for their optimal performance is as prevalent as ever. A defining characteristic, hyperparameters, can greatly affect its performance. Thus engineers go…

Neural and Evolutionary Computing · Computer Science 2020-09-21 Keshav Ganapathy

Many traditional signal recovery approaches can behave well basing on the penalized likelihood. However, they have to meet with the difficulty in the selection of hyperparameters or tuning parameters in the penalties. In this article, we…

Machine Learning · Statistics 2022-11-17 Bin Wang , Xiaofei Wang , Jianhua Guo

Motivation: Recent advances in high-throughput sequencing (HTS) have made it possible to monitor genomes in great detail. New experiments not only use HTS to measure genomic features at one time point but to monitor them changing over time…

Populations and Evolution · Quantitative Biology 2014-09-19 Hande Topa , Ágnes Jónás , Robert Kofler , Carolin Kosiol , Antti Honkela

The R package rts2 provides data manipulation and model fitting tools for Log Gaussian Cox Process (LGCP) models. LGCP models are a key method for disease and other types of surveillance, and provide a means of predicting risk across an…

Computation · Statistics 2024-03-15 Samuel I Watson

Changepoint detection is commonly formulated by minimizing the sum of in-sample losses to quantify the model's overall fit. However, for flexible modeling procedures -- especially those involving high-dimensional parameter spaces or…

Methodology · Statistics 2026-05-05 Chengde Qian , Guanghui Wang , Zhaojun Wang , Changliang Zou

We propose a new, generic and flexible methodology for nonparametric function estimation, in which we first estimate the number and locations of any features that may be present in the function, and then estimate the function parametrically…

Methodology · Statistics 2024-12-17 Rafal Baranowski , Yining Chen , Piotr Fryzlewicz

The goal of the change-point detection is to discover changes of time series distribution. One of the state of the art approaches of the change-point detection are based on direct density ratio estimation. In this work we show how existing…

Machine Learning · Computer Science 2022-06-22 Mikhail Hushchyn , Andrey Ustyuzhanin

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

The detection of change-points in a spatially or time ordered data sequence is an important problem in many fields such as genetics and finance. We derive the asymptotic distribution of a statistic recently suggested for detecting…

Statistics Theory · Mathematics 2015-10-01 Gérard Biau , Kevin Bleakley , David Mason