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Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool for quantitative fluorescence imaging because fluorescence lifetime is independent of concentration of fluorescent molecules or excitation/detection efficiency and is robust…

Structured illumination can reject out-of-focus signal from a sample, enabling high-speed and high-contrast imaging over large areas with widefield detection optics. Currently, this optical-sectioning technique is limited by image…

Fluorescence spectroscopy is an image correlation technique to analyze and characterize the molecular dynamics from a sequence of fluorescence images. Many image correlation techniques have been developed for different applications [1]. But…

Quantitative Methods · Quantitative Biology 2017-10-24 C. Chen , P. Paul-Gilloteaux , T. Vignaud , J. Salamero , F. Waharte

Diffusing Wave Spectroscopy (DWS) is an extension of standard dynamic light scattering (DLS), applied to soft materials that are turbid or opaque. The propagation of light is modeled using light diffusion, characterized by a light diffusion…

Soft Condensed Matter · Physics 2025-12-15 Manuel Helfer , Chi Zhang , Frank Scheffold

Background-free fluorescence detection in multidimensional electronic spectroscopy promises high sensitivity compared to conventional approaches. Here we explore the sensitivity limits of multidimensional electronic spectroscopy. We present…

Chemical Physics · Physics 2022-10-18 Amitav Sahu , Vivek N. Bhat , Sanjoy Patra , Vivek Tiwari

The XAFS beamline at Elettra Synchrotron in Trieste combines X-ray absorption spectroscopy and X-ray diffraction to provide chemically specific structural information of materials. It operates in the energy range 2.4-27 keV by using a…

We leverage deep learning techniques to jointly denoise and super-resolve biomedical images acquired with fluorescence microscopy. We develop a deep learning algorithm based on the networks and method described in the recent W2S paper to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-24 Martin Chatton

Experimental characterization of blood flow in living organisms is crucial for understanding the development and function of cardiovascular systems, but there have been no techniques reported for snapshot imaging of thick samples in large…

In ultrasound (US) imaging, individual channel RF measurements are back-propagated and accumulated to form an image after applying specific delays. While this time reversal is usually implemented using a hardware- or software-based…

Image and Video Processing · Electrical Eng. & Systems 2019-07-17 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Aberration-corrected optics have made electron microscopy at atomic-resolution a widespread and often essential tool for nanocharacterization. Image resolution is dominated by beam energy and the numerical aperture of the lens ({\alpha}),…

Event cameras are a bio-inspired class of sensors that asynchronously measure per-pixel intensity changes. Under fixed illumination conditions in static or low-motion scenes, rigidly mounted event cameras are unable to generate any events…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Vincenzo Polizzi , Stephen Yang , Quentin Clark , Jonathan Kelly , Igor Gilitschenski , David B. Lindell

Phase imaging is widely used in biomedical imaging, sensing, and material characterization, among other fields. However, direct imaging of phase objects with subwavelength resolution remains a challenge. Here, we demonstrate subwavelength…

Event-based vision sensors, such as the Dynamic Vision Sensor (DVS), are ideally suited for real-time motion analysis. The unique properties encompassed in the readings of such sensors provide high temporal resolution, superior sensitivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Anton Mitrokhin , Cornelia Fermuller , Chethan Parameshwara , Yiannis Aloimonos

Capturing and reconstructing high-speed dynamic 3D scenes has numerous applications in computer graphics, vision, and interdisciplinary fields such as robotics, aerodynamics, and evolutionary biology. However, achieving this using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Zihao Zou , Ziyuan Qu , Xi Peng , Vivek Boominathan , Adithya Pediredla , Praneeth Chakravarthula

Nanophotonic devices excel at confining light into intense hot spots of the electromagnetic near fields, creating unprecedented opportunities for light-matter coupling and surface-enhanced sensing. Recently, all-dielectric metasurfaces with…

Event vision sensors (neuromorphic cameras) output sparse, asynchronous ON/OFF events triggered by log-intensity threshold crossings, enabling microsecond-scale sensing with high dynamic range and low data bandwidth. As a nonlinear system,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Nimrod Kruger , Nicholas Owen Ralph , Gregory Cohen , Paul Hurley

A multispeckle technique for efficiently measuring correctly ensemble-averaged intensity autocorrelation functions of scattered light from non-ergodic and/or non-stationary systems is described. The method employs a CCD camera as a…

Soft Condensed Matter · Physics 2009-11-07 Virgile. Viasnoff , Francois Lequeux , D. J. Pine

Coherent Diffractive Imaging is a lensless technique that allows imaging of matter at a spatial resolution not limited by lens aberrations. This technique exploits the measured diffraction pattern of a coherent beam scattered by periodic…

Computational Physics · Physics 2025-08-27 Alessandro Colombo , Davide Emilio Galli , Liberato De Caro , Francesco Scattarella , Elvio Carlino

We describe a new pushbroom hyperspectral imaging device that has no macro moving part. The main components of the proposed hyperspectral imager are a digital micromirror device (DMD), a CMOS image sensor with no filter as the spectral…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Reza Arablouei , Ethan Goan , Stephen Gensemer , Branislav Kusy

Fluorescence Correlation Spectroscopy (FCS) is widely used to detect and quantify diffusion processes at the molecular level. The molecules of which diffusion is studied are marked with fluorescent dyes. It is commonly maintained that this…

Biological Physics · Physics 2018-06-12 Mathias Lechelon , Marco Pettini
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