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The transparency of deep learning models is essential for clinical diagnostics. Concept Bottleneck Model provides clear decision-making processes for diagnosis by transforming the latent space of black-box models into human-understandable…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Yiheng Dong , Yi Lin , Xin Yang

Large, publicly available clinical datasets have emerged as a novel resource for understanding disease heterogeneity and to explore personalization of therapy. These datasets are derived from data not originally collected for research…

Machine Learning · Computer Science 2025-08-14 Anish Narain , Ritam Majumdar , Nikita Narayanan , Dominic Marshall , Sonali Parbhoo

Concept-based models naturally lend themselves to the development of inherently interpretable skin lesion diagnosis, as medical experts make decisions based on a set of visual patterns of the lesion. Nevertheless, the development of these…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Cristiano Patrício , Luís F. Teixeira , João C. Neves

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

While medical Vision-Language models (VLMs) achieve strong performance on tasks such as tumor or organ segmentation and diagnosis prediction, their opaque latent representations limit clinical trust and the ability to explain predictions.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Md Rakibul Haque , KM Arefeen Sultan , Tushar Kataria , Shireen Elhabian

Concept Bottleneck Models (CBMs) provide interpretable prediction by introducing an intermediate Concept Bottleneck Layer (CBL), which encodes human-understandable concepts to explain models' decision. Recent works proposed to utilize Large…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Divyansh Srivastava , Ge Yan , Tsui-Wei Weng

Early detection of melanoma is crucial for preventing severe complications and increasing the chances of successful treatment. Existing deep learning approaches for melanoma skin lesion diagnosis are deemed black-box models, as they omit…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Deep neural networks have achieved remarkable success in computer vision; however, their black-box nature in decision-making limits interpretability and trust, particularly in safety-critical applications. Interpretability is crucial in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Ran Eisenberg , Amit Rozner , Ethan Fetaya , Ofir Lindenbaum

Concept Bottleneck Models (CBMs) ground predictions in human-understandable concepts but face fundamental limitations: the absence of a metric to pre-evaluate concept relevance, the "linearity problem" causing recent CBMs to bypass the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Merve Tapli , Quentin Bouniot , Wolfgang Stammer , Zeynep Akata , Emre Akbas

Concept-based models aim to explain model decisions with human-understandable concepts. However, most existing approaches treat concepts as numerical attributes, without providing complementary visual explanations that could localize the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Cristiano Patrício , Luís F. Teixeira , João C. Neves

We revisit language bottleneck models as an approach to ensuring the explainability of deep learning models for image classification. Because of inevitable information loss incurred in the step of converting images into language, the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Honori Udo , Takafumi Koshinaka

Continuous prompts have become widely adopted for augmenting performance across a wide range of natural language tasks. However, the underlying mechanism of this enhancement remains obscure. Previous studies rely on individual words for…

Computation and Language · Computer Science 2024-12-06 Qian Chen , Dongyang Li , Xiaofeng He

Concept Bottleneck Models (CBMs) enhance the interpretability of neural networks by basing predictions on human-understandable concepts. However, current CBMs typically rely on concept sets extracted from large language models or extensive…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Katharina Prasse , Patrick Knab , Sascha Marton , Christian Bartelt , Margret Keuper

Diabetic retinopathy is a common complication of diabetes, and monitoring the progression of retinal abnormalities using fundus imaging is crucial. Because the images must be interpreted by a medical expert, it is infeasible to screen all…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Andrea M. Storås , Josefine V. Sundgaard

Interpretable deep learning aims at developing neural architectures whose decision-making processes could be understood by their users. Among these techniqes, Concept Bottleneck Models enhance the interpretability of neural networks by…

Machine Learning · Computer Science 2024-05-28 Gabriele Dominici , Pietro Barbiero , Francesco Giannini , Martin Gjoreski , Marc Langhenirich

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Despite their success, Large-Language Models (LLMs) still face criticism due to their lack of interpretability. Traditional post-hoc interpretation methods, based on attention and gradient-based analysis, offer limited insights as they only…

Computation and Language · Computer Science 2025-07-17 Francesco De Santis , Philippe Bich , Gabriele Ciravegna , Pietro Barbiero , Danilo Giordano , Tania Cerquitelli

We propose an automated genomic interpretation module that transforms raw DNA sequences into actionable, interpretable decisions suitable for integration into medical automation and robotic systems. Our framework combines Chaos Game…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zijun Li , Jinchang Zhang , Ming Zhang , Guoyu Lu

Deep learning models have achieved strong performance in medical image analysis, but their internal decision processes remain difficult to interpret. Concept Bottleneck Models (CBMs) partially address this limitation by structuring…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Getamesay Dagnaw , Xuefei Yin , Muhammad Hassan Maqsood , Yanming Zhu , Alan Wee-Chung Liew

Many interpretable AI approaches have been proposed to provide plausible explanations for a model's decision-making. However, configuring an explainable model that effectively communicates among computational modules has received less…

Machine Learning · Computer Science 2023-11-09 Jinyung Hong , Keun Hee Park , Theodore P. Pavlic