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Retrieval-augmented generation (RAG) techniques leverage the in-context learning capabilities of large language models (LLMs) to produce more accurate and relevant responses. Originating from the simple 'retrieve-then-read' approach, the…

Computation and Language · Computer Science 2024-07-16 Yunxiao Shi , Xing Zi , Zijing Shi , Haimin Zhang , Qiang Wu , Min Xu

This paper presents a novel method to make statistical inferences for both the model support and regression coefficients in a high-dimensional logistic regression model. Our method is based on the repro samples framework, in which we…

Methodology · Statistics 2024-03-18 Xiaotian Hou , Linjun Zhang , Peng Wang , Min-ge Xie

With the rapid advancement of retrieval-augmented vision-language models, multimodal medical retrieval-augmented generation (MMed-RAG) systems are increasingly adopted in clinical decision support. These systems enhance medical applications…

Cryptography and Security · Computer Science 2025-11-25 Yingjia Shang , Yi Liu , Huimin Wang , Furong Li , Wenfang Sun , Wu Chengyu , Yefeng Zheng

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Diffusion bridge models establish probabilistic paths between arbitrary paired distributions and exhibit great potential for universal image restoration. Most existing methods merely treat them as simple variants of stochastic interpolants,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Hebaixu Wang , Jing Zhang , Haoyang Chen , Haonan Guo , Di Wang , Jiayi Ma , Bo Du

Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr

Controllable layout generation aims to create plausible visual arrangements of element bounding boxes within a graphic design according to certain optional constraints, such as the type or position of a specific component. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Yuxuan Wu , Le Wang , Sanping Zhou , Mengnan Liu , Gang Hua , Haoxiang Li

Augmentation by generative modelling yields a promising alternative to the accumulation of surgical data, where ethical, organisational and regulatory aspects must be considered. Yet, the joint synthesis of (image, mask) pairs for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yannik Frisch , Christina Bornberg , Moritz Fuchs , Anirban Mukhopadhyay

Traditional reconstruction-based methods have struggled to achieve competitive performance in anomaly detection. In this paper, we introduce Denoising Diffusion Anomaly Detection (DDAD), a novel denoising process for image reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Arian Mousakhan , Thomas Brox , Jawad Tayyub

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Unrestricted adversarial attacks present a serious threat to deep learning models and adversarial defense techniques. They pose severe security problems for deep learning applications because they can effectively bypass defense mechanisms.…

Machine Learning · Computer Science 2024-07-16 Xuelong Dai , Kaisheng Liang , Bin Xiao

This work focuses on the problem of reconstructing a 3D human body mesh from a given 2D image. Despite the inherent ambiguity of the task of human mesh recovery, most existing works have adopted a method of regressing a single output. In…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Hanbyel Cho , Junmo Kim

Adeno-associated viral (AAV) vectors are widely used delivery platforms in gene therapy, and the design of improved capsids is key to expanding their therapeutic potential. A central challenge in AAV bioengineering, as in protein design…

Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Effectively addressing the challenge of industrial Anomaly Detection (AD) necessitates an ample supply of defective samples, a constraint often hindered by their scarcity in industrial contexts. This paper introduces a novel algorithm…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Hanxi Li , Zhengxun Zhang , Hao Chen , Lin Wu , Bo Li , Deyin Liu , Mingwen Wang

Over the past decade, antibodies have steadily grown in therapeutic importance thanks to their high specificity and low risk of adverse effects compared to other drug modalities. While traditional antibody discovery is primarily wet lab…

Biomolecules · Quantitative Biology 2023-09-26 Jordan Venderley

Recently, reconstruction-based methods have gained attention for AIGC image detection. These methods leverage pre-trained diffusion models to reconstruct inputs and measure residuals for distinguishing real from fake images. Their key…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Qingyu Liu , Zhongjie Ba , Jianmin Guo , Qiu Wang , Zhibo Wang , Jie Shi , Kui Ren

Denoising diffusion models have emerged as the go-to generative framework for solving inverse problems in imaging. A critical concern regarding these models is their performance on out-of-distribution tasks, which remains an under-explored…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Riccardo Barbano , Alexander Denker , Hyungjin Chung , Tae Hoon Roh , Simon Arridge , Peter Maass , Bangti Jin , Jong Chul Ye

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai
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