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The numerical simulation of cardiac electrophysiology is a highly challenging problem in scientific computing. The Bidomain system is the most complete mathematical model of cardiac bioelectrical activity. It consists of an elliptic and a…

Numerical Analysis · Mathematics 2023-11-27 Edoardo Centofanti , Simone Scacchi

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

We analyze a Balancing Domain Decomposition by Constraints (BDDC) preconditioner for the solution of three dimensional composite Discontinuous Galerkin discretizations of reaction-diffusion systems of ordinary and partial differential…

In this work, we provide a performance comparison between the Balancing Domain Decomposition by Constraints (BDDC) and the Algebraic Multigrid (AMG) preconditioners for cardiac mechanics on both structured and unstructured finite element…

Numerical Analysis · Mathematics 2022-08-15 Nicolás A. Barnafi , Luca F. Pavarino , Simone Scacchi

Cardiac electrophysiology (CEP) simulations are increasingly used for understanding cardiac arrhythmias and guiding clinical decisions. However, these simulations typically require high-performance computing resources with numerous CPU…

Software Engineering · Computer Science 2025-10-15 Bei Zhou , Maximilian Balmus , Cesare Corrado , Ludovica Cicci , Shuang Qian , Steven A. Niederer

The bidomain model is widely used in electro-cardiology to simulate spreading of excitation in the myocardium and electrocardiograms. It consists of a system of two parabolic reaction diffusion equations coupled with an ODE system. Its…

Numerical Analysis · Mathematics 2017-12-06 Charles Pierre

We present an efficient open-source implementation of the multiparticle collision dynamics (MPCD) algorithm that scales to run on hundreds of graphics processing units (GPUs). We especially focus on optimizations for modern GPU…

Soft Condensed Matter · Physics 2018-08-01 Michael P. Howard , Athanassios Z. Panagiotopoulos , Arash Nikoubashman

A range of computational biology software (GROMACS, AMBER, NAMD, LAMMPS, OpenMM, Psi4 and RELION) was benchmarked on a representative selection of HPC hardware, including AMD EPYC 7742 CPU nodes, NVIDIA V100 and AMD MI250X GPU nodes, and an…

The reliability of cardiovascular computational models depends on the accurate solution of the hemodynamics, the realistic characterization of the hyperelastic and electric properties of the tissues along with the correct description of…

The exponential growth of floating point power in graphics processing units (GPUs), together with their low cost, has given rise to an attractive platform upon which to deploy lattice QCD calculations. GPUs are essentially many (O(100))…

High Energy Physics - Lattice · Physics 2010-11-05 M. A. Clark

Current deep learning algorithms designed for automatic ECG analysis have exhibited notable accuracy. However, akin to traditional electrocardiography, they tend to be narrowly focused and typically address a singular diagnostic condition.…

Signal Processing · Electrical Eng. & Systems 2024-05-14 Nils Strodthoff , Juan Miguel Lopez Alcaraz , Wilhelm Haverkamp

Training large language models requires extensive processing, made possible by many high-performance computing resources. This study compares multi-node and multi-GPU environments for training large language models of electrocardiograms. It…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-28 Dimitar Mileski , Nikola Petrovski , Marjan Gusev

Molecular dynamics (MD) simulation is a powerful computational tool to study the behavior of macromolecular systems. But many simulations of this field are limited in spatial or temporal scale by the available computational resource. In…

Computational Physics · Physics 2010-01-22 Ji Xu , Ying Ren , Wei Ge , Xiang Yu , Xiaozhen Yang , Jinghai Li

The study of biological systems witnessed a pervasive cross-fertilization between experimental investigation and computational methods. This gave rise to the development of new methodologies, able to tackle the complexity of biological…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Daniela Besozzi , Giulio Caravagna , Paolo Cazzaniga , Marco Nobile , Dario Pescini , Alessandro Re

In recent years, it has become increasingly common for high performance computers (HPC) to possess some level of heterogeneous architecture - typically in the form of GPU accelerators. In some machines these are isolated within a dedicated…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-19 I. Zacharoudiou , J. W. S. McCullough , P. V. Coveney

Obtaining a thermodynamically accurate phase diagram through numerical calculations is a computationally expensive problem that is crucially important to understanding the complex phenomena of solid state physics, such as superconductivity.…

Computational Physics · Physics 2015-05-20 Michał Januszewski , Andrzej Ptok , Dawid Crivelli , Bartłomiej Gardas

The purpose of the Evaluating ECG capturing using sound-card of PC/Laptop is provided portable and low cost ECG monitoring system using laptop and mobile phones. There is no need to interface micro controller or any other device to transmit…

Other Computer Science · Computer Science 2014-02-18 Bhavikkumar Patel , Dhrumil Shah

The high arithmetic performance and intrinsic parallelism of recent graphical processing units (GPUs) can offer a technological edge for molecular dynamics simulations. ACEMD is a production-class bio-molecular dynamics (MD) simulation…

Computational Physics · Physics 2009-02-06 M. J. Harvey , G. Giupponi , G. De Fabritiis

We introduce a multiphysics and geometric multiscale computational model, suitable to describe the hemodynamics of the whole human heart, driven by a four-chamber electromechanical model. We first present a study on the calibration of the…

Numerical Analysis · Mathematics 2024-03-06 Alberto Zingaro , Michele Bucelli , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

We present a case-study on the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods. Graphics cards, containing multiple Graphics Processing Units (GPUs), are self-contained parallel…

Computation · Statistics 2015-05-05 Anthony Lee , Christopher Yau , Michael B. Giles , Arnaud Doucet , Christopher C. Holmes
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