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While large language models (LLMs) excel at static scientific reasoning, they struggle to model the temporal structure of dynamic physical processes. We present EvoMD-LLM (Evolutionary Molecular Dynamics Large Language Model), a framework…

Artificial Intelligence · Computer Science 2026-05-29 Zhichen Tang , Zhengzheng Dang , Yulin Chen , Jixin Wu , Haiwen Li , Yanming Wang

Large Language Models (LLMs) have shown immense potential in enhancing various aspects of our daily lives, from conversational AI to search and AI assistants. However, their growing capabilities come at the cost of extremely large model…

Machine Learning · Computer Science 2025-02-27 Yingyu Liang , Jiangxuan Long , Zhenmei Shi , Zhao Song , Yufa Zhou

Post-training pruning, as one of the key techniques for compressing large language models, plays a vital role in lightweight model deployment and model sparsity. However, current mainstream pruning methods dependent on the Hessian matrix…

Machine Learning · Computer Science 2025-05-20 Yuhan Kang , Yang Shi , Mei We , Jun He , Jianchao Yang , Zeyu Xue , Jing Feng , Xinwang Liu

The impressive performance of Large Language Models (LLMs) across various natural language processing tasks comes at the cost of vast computational resources and storage requirements. One-shot pruning techniques offer a way to alleviate…

Machine Learning · Computer Science 2025-09-09 Xiang Meng , Kayhan Behdin , Haoyue Wang , Rahul Mazumder

Prompt compression methods enhance the efficiency of Large Language Models (LLMs) and minimize the cost by reducing the length of input context. The goal of prompt compression is to shorten the LLM prompt while maintaining a high generation…

Computation and Language · Computer Science 2025-08-25 Tinghui Zhang , Yifan Wang , Daisy Zhe Wang

Large Language Models (LLMs) have demonstrated strong capabilities in natural language understanding and reasoning, while recent extensions that incorporate visual inputs enable them to process multimodal information. Despite these…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Pengcheng Zheng , Chaoning Zhang , Ya Wen , Wang Liu , Qigan Sun , Jiarong Mo , Jiaquan Zhang , Jewon Lee , Tae-Ho Kim , Kuien Liu , Tianyu Li , Caiyan Qin , Yang Yang

Large Reasoning Models (LRMs) have demonstrated impressive capabilities but suffer from cognitive inefficiencies like "overthinking" simple problems and "underthinking" complex ones. While existing methods that use supervised fine-tuning…

Artificial Intelligence · Computer Science 2026-03-24 Tian Liang , Wenxiang Jiao , Zhiwei He , Jiahao Xu , Haitao Mi , Dong Yu

Proteins are shaped by gradual evolution under biophysical and functional constraints. Protein language models learn rich evolutionary constraints from large-scale sequences, and discrete diffusion-based protein language models~(\eg, DPLMs)…

Machine Learning · Computer Science 2026-05-14 Xinyou Wang , Liang Hong , Jiasheng Ye , Zaixiang Zheng , Yu Li , Shujian Huang , Quanquan Gu

As Large Language Models (LLMs) continue to scale, post-training pruning has emerged as a promising approach to reduce computational costs while preserving performance. Existing methods such as SparseGPT and Wanda achieve high sparsity…

Computation and Language · Computer Science 2026-01-15 Sai Varun Kodathala , Rakesh Vunnam

Multimodal large language models (MLLMs) incur substantial inference cost due to the processing of hundreds of visual tokens per image. Although token pruning has proven effective for accelerating inference, determining when and where to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Yahong Wang , Juncheng Wu , Zhangkai Ni , Chengmei Yang , Yihang Liu , Longzhen Yang , Yuyin Zhou , Ying Wen , Lianghua He

How can we accelerate large language models(LLMs) without sacrificing accuracy? The slow inference speed of LLMs hinders us to benefit from their remarkable performance in diverse applications. This is mainly because numerous sublayers are…

Computation and Language · Computer Science 2025-06-05 Seungcheol Park , Sojin Lee , Jongjin Kim , Jinsik Lee , Hyunjik Jo , U Kang

In spite of strong performance achieved by LLMs, the costs of their deployment are unaffordable. For the compression of LLMs, gradient-based pruning methods present promising effectiveness. However, in these methods, the gradient…

Computation and Language · Computer Science 2025-06-16 Hourun Zhu , Chengchao Shen

Structural pruning techniques are essential for deploying multimodal large language models (MLLMs) across various hardware platforms, from edge devices to cloud servers. However, current pruning methods typically determine optimal…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Zhihan Zhang , Xiang Pan , Hongchen Wei , Zhenzhong Chen

As Large Language Models (LLMs) continue to grow in size, storing and transmitting them on edge devices becomes increasingly challenging. Traditional methods like quantization and pruning struggle to achieve extreme compression of LLMs…

Machine Learning · Computer Science 2025-11-25 Ye Tian , Chengcheng Wang , Jing Han , Yehui Tang , Kai Han

Large-scale AI models, such as Large Language Models (LLMs) and Diffusion Models (DMs), have grown rapidly in size, creating significant challenges for efficient deployment on resource-constrained hardware. In this paper, we introduce…

Machine Learning · Computer Science 2026-01-05 Tianyi Zhang , Mohsen Hariri , Shaochen Zhong , Vipin Chaudhary , Yang Sui , Xia Hu , Anshumali Shrivastava

Language models (LMs) excel at tasks across diverse domains, yet require substantial computational resources during inference. Compression techniques such as pruning and quantization offer a practical path towards efficient LM deployment,…

Computation and Language · Computer Science 2026-02-26 Miles Williams , George Chrysostomou , Vitor Jeronymo , Nikolaos Aletras

Leveraging large language models (LLMs) for complex natural language tasks typically requires long-form prompts to convey detailed requirements and information, which results in increased memory usage and inference costs. To mitigate these…

Computation and Language · Computer Science 2024-10-18 Zongqian Li , Yinhong Liu , Yixuan Su , Nigel Collier

Pre-trained Vision-Language Models (VLMs) have been exploited in various Computer Vision tasks (e.g., few-shot recognition) via model adaptation, such as prompt tuning and adapters. However, existing adaptation methods are designed by human…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kun Ding , Ying Wang , Shiming Xiang

Although large language models (LLMs) have achieved revolutionary breakthroughs in many fields, their large model size and high computational cost pose significant challenges for practical deployment on resource-constrained edge devices. To…

Machine Learning · Computer Science 2025-10-29 Yao Lu , Yuqi Li , Wenbin Xie , Shanqing Yu , Qi Xuan , Zhaowei Zhu , Shiping Wen

Large Vision-Language Models (LVLMs) represent a significant advancement toward achieving superior multimodal capabilities by enabling powerful Large Language Models (LLMs) to understand visual input. Typically, LVLMs utilize visual…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Lei Jiang , Weizhe Huang , Tongxuan Liu , Yuting Zeng , Jing Li , Lechao Cheng , Xiaohua Xu