English
Related papers

Related papers: Intrinsic cell-to-cell variance from experimental …

200 papers

Stochasticity is both exploited and controlled by cells. Although the intrinsic stochasticity inherent in biochemistry is relatively well understood, cellular variation, or 'noise', is predominantly generated by interactions of the system…

Molecular Networks · Quantitative Biology 2008-09-18 Vahid Shahrezaei , Julien F Ollivier , Peter S Swain

Internal shocks between propagating plasma shells, originally ejected at different times with different velocities are believed to play a major role in dissipating the kinetic energy, thereby explaining the observed lightcurve and spectra…

High Energy Astrophysical Phenomena · Physics 2017-09-06 Asaf Pe'er , Killian Long , Piergiorgio Casella

The generalized Langevin equation (GLE) is a universal model for particle velocity in a viscoelastic medium. In this paper, we consider the GLE family with fractional memory kernels. We show that, in the critical regime where the memory…

Probability · Mathematics 2021-03-10 Gustavo Didier , Hung D. Nguyen

The dynamics of unimolecular photo-triggered reactions can be strongly affected by the surrounding medium. An accurate description of these reactions requires knowing the free energy surface (FES) and the friction felt by the reactants.…

A single solid tumor, composed of nearly identical cells, exhibits heterogeneous dynamics. Cells dynamics in the core is glass-like whereas those in the periphery undergo diffusive or super-diffusive behavior. Quantification of…

Biological Physics · Physics 2020-11-24 Sumit Sinha , D. Thirumalai

We present experiments on the collective dynamics of macroscopic photoactive self-propelled particles subjected to spatiotemporally varying excitation. The particles move within an arena divided into two regions with different illumination…

Soft Condensed Matter · Physics 2026-03-19 Sára Lévay , Axel Katona , Raúl Cruz Hidalgo , Iker Zuriguel

Interpreting the vibrational properties of amorphous solids beyond Debye's theory is challenging due to the presence of inhomogeneity on the mesoscopic scale. In this work, we model this inhomogeneity by real-space fluctuating elasticity…

Soft Condensed Matter · Physics 2026-04-03 Cunyuan Jiang

Standard Reaction-Diffusion (RD) systems are characterized by infinite velocities and no persistence in the movement of individuals, two conditions that are violated when considering living organisms. Here we consider a discrete particle…

Biological Physics · Physics 2019-01-09 Davide Vergni , Stefano Berti , Angelo Vulpiani , Massimo Cencini

Understanding human mobility is important for the development of intelligent mobile service robots as it can provide prior knowledge and predictions of human distribution for robot-assisted activities. In this paper, we propose a…

Human-Computer Interaction · Computer Science 2016-06-29 Bo Tang , Chao Jiang , Haibo He , Yi Guo

The stochastic dynamics of a rigid inclusion constrained to move on a curved surface has many applications in biological and soft matter physics, ranging from the diffusion of passive or active membrane proteins to the motion of phoretic…

Soft Condensed Matter · Physics 2025-04-18 Balázs Németh , Ronojoy Adhikari

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

We introduce a class of discrete random walk model driven by global memory effects. At any time the right-left transitions depend on the whole previous history of the walker, being defined by an urn-like memory mechanism. The characteristic…

Statistical Mechanics · Physics 2016-12-28 Adrian A. Budini

Traditional survival analysis techniques focus on the occurrence of failures over the time. During analysis of such events, ignoring the related unobserved covariates or heterogeneity involved in data sample may leads us to adverse…

Methodology · Statistics 2021-12-22 Shikhar Tyagi , Arvind Pandey , David D Hanagal

During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process. The continuous positional information…

Molecular Networks · Quantitative Biology 2017-02-08 Ruben Perez-Carrasco , Pilar Guerrero , James Briscoe , Karen Page

We characterize the dynamic non-equilibrium steady state behavior of active particles using density fluctuations in the system. We analyze the effective local density around a particle in the steady state and numerically calculate its mean,…

Statistical Mechanics · Physics 2025-04-22 Jayam Joshi , Pawan Kumar Mishra , Shradha Mishra

When plated onto substrates, cell morphology and even stem cell differentiation are influenced by the stiffness of their environment. Stiffer substrates give strongly spread (eventually polarized) cells with strong focal adhesions, and…

Subcellular Processes · Quantitative Biology 2018-10-05 Samuel Bell , Anna-Lena Redmann , Eugene M. Terentjev

Social dynamics is concerned primarily with interactions among individuals and the resulting group behaviors, modeling the temporal evolution of social systems via the interactions of individuals within these systems. In particular, the…

Machine Learning · Statistics 2016-11-08 Zhen Xu , Wen Dong , Sargur Srihari

Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented. It consists of internal dynamics of a unit, interaction…

adap-org · Physics 2015-06-24 Kunihiko Kaneko

In this paper we use an individual-based model and its associated kinetic equation to study the generation of long jumps in the motion of E. coli. These models relate the run-and-tumble process to the intracellular reaction where the…

Analysis of PDEs · Mathematics 2019-11-11 Weiran Sun , Min Tang , Xiaoru Xue

Intracellular transport of large cargoes, such as organelles, vesicles or large proteins, is a complex dynamical process that involves the interplay of ATP-consuming molecular motors, cytoskeleton filaments and the viscoelastic cytoplasm.…

Biological Physics · Physics 2013-05-29 L. Bruno , V. Levi , M. Brunstein , M. A. Despósito