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Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding, reasoning, and problem-solving across various domains. However, their ability to perform complex, multi-step reasoning task-essential…

Legal syllogism is a form of deductive reasoning commonly used by legal professionals to analyze cases. In this paper, we propose legal syllogism prompting (LoT), a simple prompting method to teach large language models (LLMs) for legal…

Computation and Language · Computer Science 2023-07-18 Cong Jiang , Xiaolei Yang

Pretrained large language models (LLMs) are widely used in many sub-fields of natural language processing (NLP) and generally known as excellent few-shot learners with task-specific exemplars. Notably, chain of thought (CoT) prompting, a…

Computation and Language · Computer Science 2023-01-31 Takeshi Kojima , Shixiang Shane Gu , Machel Reid , Yutaka Matsuo , Yusuke Iwasawa

Reinforcement learning (RL)-based dynamic treatment regimes (DTRs) hold promise for automating complex clinical decision-making, yet their practical deployment remains hindered by the intensive engineering required to inject clinical…

Machine Learning · Computer Science 2025-08-08 Zhiyao Luo , Tingting Zhu

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

Computation and Language · Computer Science 2025-12-30 Mengdi Chai , Ali R. Zomorrodi

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

As a cornerstone of patient care, clinical decision-making significantly influences patient outcomes and can be enhanced by large language models (LLMs). Although LLMs have demonstrated remarkable performance, their application to visual…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Ji Young Byun , Young-Jin Park , Navid Azizan , Rama Chellappa

Artificially intelligent (AI) co-scientists must be able to sift through research literature cost-efficiently while applying nuanced scientific reasoning. We evaluate Small Language Models (SLMs, <= 8B parameters) for classifying medical…

Computational Engineering, Finance, and Science · Computer Science 2025-12-09 Muhammed Muaaz Dawood , Mohammad Zaid Moonsamy , Kaela Kokkas , Hairong Wang , Robert F. Breiman , Richard Klein , Emmanuel K. Sekyi , Bruce A. Bassett

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen

Syllogistic reasoning is crucial for sound legal decision-making, allowing legal professionals to draw logical conclusions by applying general principles to specific case facts. While large language models (LLMs) can answer legal questions,…

Computation and Language · Computer Science 2025-06-02 Kepu Zhang , Weijie Yu , Zhongxiang Sun , Jun Xu

Recently, large language models (LLMs) have taken the spotlight in natural language processing. Further, integrating LLMs with vision enables the users to explore emergent abilities with multimodal data. Visual language models (VLMs), such…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Minh-Hao Van , Prateek Verma , Xintao Wu

Large language models (LLMs) and theorem provers (TPs) can be effectively combined for verifiable natural language inference (NLI). However, existing approaches rely on a fixed logical formalism, a feature that limits robustness and…

Artificial Intelligence · Computer Science 2026-01-12 Ali Farjami , Luca Redondi , Marco Valentino

Recent years have seen the rise of large language models (LLMs), where practitioners use task-specific prompts; this was shown to be effective for a variety of tasks. However, when applied to semantic textual similarity (STS) and natural…

Computation and Language · Computer Science 2024-02-06 Yuxia Wang , Minghan Wang , Preslav Nakov

Despite their linguistic competence, Large Language Models (LLMs) often struggle to reason reliably and flexibly. To identify these shortcomings, we introduce the Non-Linear Reasoning (NLR) dataset, a collection of 55 unique, hand-designed…

Computation and Language · Computer Science 2025-12-02 Nasim Borazjanizadeh , Steven T. Piantadosi