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Image registration is an essential technique for the analysis of Computed Tomography (CT) images in clinical practice. However, existing methodologies are predominantly tailored to a specific organ of interest and often exhibit lower…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Xuan Loc Pham , Mathias Prokop , Bram van Ginneken , Alessa Hering

Histological analysis plays a crucial role in understanding tissue structure and pathology. While recent advancements in registration methods have improved 2D histological analysis, they often struggle to preserve critical 3D spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Juming Xiong , Ruining Deng , Jialin Yue , Siqi Lu , Junlin Guo , Marilyn Lionts , Tianyuan Yao , Can Cui , Junchao Zhu , Chongyu Qu , Mengmeng Yin , Haichun Yang , Yuankai Huo

Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Jiazheng Wang , Xiang Chen , Yuxi Zhang , Min Liu , Yaonan Wang , Hang Zhang

Ultrasound imaging is a cost-effective and radiation-free modality for visualizing anatomical structures in real-time, making it ideal for guiding surgical interventions. However, its limited field-of-view, speckle noise, and imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Remi Delaunay , Ruisi Zhang , Filipe C. Pedrosa , Navid Feizi , Dianne Sacco , Rajni Patel , Jayender Jagadeesan

This paper presents a review of deep learning (DL) based medical image registration methods. We summarized the latest developments and applications of DL-based registration methods in the medical field. These methods were classified into…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Yabo Fu , Yang Lei , Tonghe Wang , Walter J. Curran , Tian Liu , Xiaofeng Yang

Multi-modal image registration is a challenging problem that is also an important clinical task for many real applications and scenarios. As a first step in analysis, deformable registration among different image modalities is often…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Fengze Liu , Jinzheng Cai , Yuankai Huo , Chi-Tung Cheng , Ashwin Raju , Dakai Jin , Jing Xiao , Alan Yuille , Le Lu , ChienHung Liao , Adam P Harrison

Whole slide image (WSI) registration is an essential task for analysing the tumour microenvironment (TME) in histopathology. It involves the alignment of spatial information between WSIs of the same section or serial sections of a tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Behnaz Elhaminia , Abdullah Alsalemi , Esha Nasir , Mostafa Jahanifar , Ruqayya Awan , Lawrence S. Young , Nasir M. Rajpoot , Fayyaz Minhas , Shan E Ahmed Raza

Image registration plays an important role in comparing images. It is particularly important in analyzing medical images like CT, MRI, PET, etc. to quantify different biological samples, to monitor disease progression and to fuse different…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

Unsupervised learning strategy is widely adopted by the deformable registration models due to the lack of ground truth of deformation fields. These models typically depend on the intensity-based similarity loss to obtain the learning…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Luyi Han , Haoran Dou , Yunzhi Huang , Pew-Thian Yap

This work presents a proof-of-concept solution designed to improve the accuracy of radiographic feature characterisation in pre-surgical CT/MR volumes. The solution involves 3D co-location of 2D digital histology slides within ex-vivo,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Robert Phillips , Constantine Zakkaroff , Keren Dittmer , Nicholas Robillard , Kenzie Baer , Anthony Butler

Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Vasiliki Sideri-Lampretsa , Georgios Kaissis , Daniel Rueckert

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Yang Lei , Luke A. Matkovic , Justin Roper , Tonghe Wang , Jun Zhou , Beth Ghavidel , Mark McDonald , Pretesh Patel , Xiaofeng Yang

In breast surgical planning, accurate registration of MR images across patient positions has the potential to improve the localisation of tumours during breast cancer treatment. While learning-based registration methods have recently become…

Deformable registration consists of finding the best dense correspondence between two different images. Many algorithms have been published, but the clinical application was made difficult by the high calculation time needed to solve the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Theophraste Henry , Marvin Lerousseau , Amaury Leroy , Nikos Paragios , Eric Deutsch

Unsafe surgical care is a critical health concern, often linked to limitations in surgeon experience, skills, and situational awareness. Integrating patient-specific 3D models into the surgical field can enhance visualization, provide…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Alberto Neri , Veronica Penza , Nazim Haouchine , Leonardo S. Mattos

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Image-based navigation is widely considered the next frontier of minimally invasive surgery. It is believed that image-based navigation will increase the access to reproducible, safe, and high-precision surgery as it may then be performed…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Mathias Unberath , Cong Gao , Yicheng Hu , Max Judish , Russell H Taylor , Mehran Armand , Robert Grupp

CLARITY is a method for converting biological tissues into translucent and porous hydrogel-tissue hybrids. This facilitates interrogation with light sheet microscopy and penetration of molecular probes while avoiding physical slicing. In…

Computer Vision and Pattern Recognition · Computer Science 2017-08-14 Kwame S. Kutten , Nicolas Charon , Michael I. Miller , J. T. Ratnanather , Jordan Matelsky , Alexander D. Baden , Kunal Lillaney , Karl Deisseroth , Li Ye , Joshua T. Vogelstein

Image registration (IR) is a process that deforms images to align them with respect to a reference space, making it easier for medical practitioners to examine various medical images in a standardized reference frame, such as having the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Ahmad Hammoudeh , Stéphane Dupont

Three-dimensional (3D) images, such as CT, MRI, and PET, are common in medical imaging applications and important in clinical diagnosis. Semantic ambiguity is a typical feature of many medical image labels. It can be caused by many factors,…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Lin Wang , Xiufen Ye , Donghao Zhang , Wanji He , Lie Ju , Xin Wang , Wei Feng , Kaimin Song , Xin Zhao , Zongyuan Ge