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Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical…

Computation and Language · Computer Science 2026-05-12 Zongxian Yang , Jiayu Qian , Kay Chen Tan , Hau-San Wong , Yulong Chen , Haoyu Zhang , Zhi-An Huang

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

Retrieval-augmented generation (RAG) has improved large language models (LLMs) by using knowledge retrieval to overcome knowledge deficiencies. However, current RAG methods often fall short of ensuring the depth and completeness of…

Computation and Language · Computer Science 2025-02-11 Shengjie Ma , Chengjin Xu , Xuhui Jiang , Muzhi Li , Huaren Qu , Cehao Yang , Jiaxin Mao , Jian Guo

With the rise of knowledge graph based retrieval-augmented generation (RAG) techniques such as GraphRAG and Pike-RAG, the role of knowledge graphs in enhancing the reasoning capabilities of large language models (LLMs) has become…

Information Retrieval · Computer Science 2025-04-15 Hairong Zhang , Jiaheng Si , Guohang Yan , Boyuan Qi , Pinlong Cai , Song Mao , Ding Wang , Botian Shi

Constructing domain-specific knowledge graphs from unstructured text remains challenging due to heterogeneous entity mentions, long-tail relation distributions, and the absence of standardized schemas. We present LEC-KG, a bidirectional…

Computation and Language · Computer Science 2026-03-02 Yikai Zeng , Yingchao Piao , Changhua Pei , Jianhui Li

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Large Language Models (LLMs) show great promise as a powerful tool for scientific literature exploration. However, their effectiveness in providing scientifically accurate and comprehensive answers to complex questions within specialized…

Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Dmitriy Dligach , Timothy A. Miller , Samantha Barr , Yanjun Gao , Matthew Churpek , Anoop Mayampurath , Majid Afshar

Large language models (LLMs) achieve optimal utility when their responses are grounded in external knowledge sources. However, real-world documents, such as annual reports, scientific papers, and clinical guidelines, frequently combine…

Information Retrieval · Computer Science 2025-12-17 Chi Zhang , Qiyang Chen , Mengqi Zhang

In real-world scientific discovery, human beings always make use of the accumulated prior knowledge with imagination pick select one or a few most promising hypotheses from large and noisy data analysis results. In this study, we introduce…

Machine Learning · Computer Science 2025-01-29 Haoran Song , Jiarui Feng , Guangfu Li , Michael Province , Philip Payne , Yixin Chen , Fuhai Li

This paper introduces a novel, multi-source framework for the relational validation of Large Language Models (LLMs). While existing benchmarks have demonstrated LLMs' proficiency at factual recall, their ability to understand and reproduce…

Social and Information Networks · Computer Science 2026-05-22 Moses Boudourides

The recent advances in large language models (LLM) and foundation models with emergent capabilities have been shown to improve the performance of many NLP tasks. LLMs and Knowledge Graphs (KG) can complement each other such that LLMs can be…

Computation and Language · Computer Science 2023-08-07 Nandana Mihindukulasooriya , Sanju Tiwari , Carlos F. Enguix , Kusum Lata

Large language models (LLMs) have shown strong potential across a variety of tasks, but their application in the telecom field remains challenging due to domain complexity, evolving standards, and specialized terminology. Therefore,…

Artificial Intelligence · Computer Science 2026-02-20 Dun Yuan , Hao Zhou , Xue Liu , Hao Chen , Yan Xin , Jianzhong , Zhang

Large Language Models (LLMs) are often challenged by generating erroneous or hallucinated responses, especially in complex reasoning tasks. Leveraging Knowledge Graphs (KGs) as external knowledge sources has emerged as a viable solution.…

Artificial Intelligence · Computer Science 2025-05-23 Yuan Sui , Yufei He , Nian Liu , Xiaoxin He , Kun Wang , Bryan Hooi

Large language models (LLMs) has become a significant research focus and is utilized in various fields, such as text generation and dialog systems. One of the most essential applications of LLM is Retrieval Augmented Generation (RAG), which…

Computation and Language · Computer Science 2025-10-06 Sicheng Dong , Vahid Zolfaghari , Nenad Petrovic , Alois Knoll

Knowledge graphs play a vital role in numerous artificial intelligence tasks, yet they frequently face the issue of incompleteness. In this study, we explore utilizing Large Language Models (LLM) for knowledge graph completion. We consider…

Computation and Language · Computer Science 2025-02-14 Liang Yao , Jiazhen Peng , Chengsheng Mao , Yuan Luo

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

Computation and Language · Computer Science 2025-01-30 Vahan Arsenyan , Spartak Bughdaryan , Fadi Shaya , Kent Small , Davit Shahnazaryan

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

The rapid expansion of medical literature presents growing challenges for structuring and integrating domain knowledge at scale. Knowledge Graphs (KGs) offer a promising solution by enabling efficient retrieval, automated reasoning, and…

Computation and Language · Computer Science 2025-08-20 Duzhen Zhang , Zixiao Wang , Zhong-Zhi Li , Yahan Yu , Shuncheng Jia , Jiahua Dong , Haotian Xu , Xing Wu , Yingying Zhang , Tielin Zhang , Jie Yang , Xiuying Chen , Le Song