Related papers: Turing chemotactic instability in an HIV model
We derive a necessary and sufficient condition for Turing instabilities to occur in two-component systems of reaction-diffusion equations with Neumann boundary conditions. We apply this condition to reaction-diffusion systems built from…
This paper investigates the dynamics of immune response and autoimmunity with particular emphasis on the role of regulatory T cells (Tregs), T cells with different activation thresholds, and cytokines in mediating T cell activity. Analysis…
The control of opportunistic infections among HIV infected individuals should be one of the major public health concerns in reducing mortality rate of individuals living with HIV/AIDS. In this study a deterministic co-infection mathematical…
Spatial distribution of the human population is distinctly heterogeneous, e.g. showing significant difference in the population density between urban and rural areas. In the historical perspective, i.e. on the timescale of centuries, the…
Sexual partnerships that overlap in time (concurrent relationships) may play a significant role in the HIV epidemic, but the precise effect is unclear. We derive edge-based compartmental models of disease spread in idealized dynamic…
The problem of Turing instabilities for a reaction-diffusion system defined on a complex Cartesian product networks is considered. To this end we operate in the linear regime and expand the time dependent perturbation on a basis formed by…
The rheological properties of biological tissues are core to processes such as cancer metastasis, wound healing and embryo development. The emergence of tissue and organ structures during morphogenesis requires the precise formation of…
One way in which the human immunodeficiency virus (HIV-1) replicates within a host is by infecting activated CD4+ T-cells, which then produce additional copies of the virus. Even with the introduction of antiretroviral drug therapy, which…
The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating…
A class of hyperbolic reaction--diffusion models with cross-diffusion is derived within the context of Extended Thermodynamics. Linear stability analysis is performed to study the nature of the equilibrium states against uniform and…
GTPase molecules are important regulators in cells that continuously run through an activation/deactivation and membrane-attachment/membrane-detachment cycle. Activated GTPase is able to localize in parts of the membranes and to induce cell…
In this paper, we propose a delayed cytokine-enhanced viral infection model incorporating saturation incidence and immune response. We compute the basic reproduction numbers and introduce a convex cone to discuss the impact of non-negative…
We propose and study a new mathematical model of the human immunodeficiency virus (HIV). The main novelty is to consider that the antibody growth depends not only on the virus and on the antibodies concentration but also on the uninfected…
Spatial patterns arising spontaneously due to internal processes are ubiquitous in nature, varying from regular patterns of dryland vegetation to complex structures of bacterial colonies. Many of these patterns can be explained in the…
Up to now, the effects of having heterogeneous networks of contacts have been studied mostly for diseases which are not persistent in time, i.e., for diseases where the infectious period can be considered very small compared to the lifetime…
We propose a fractional order model for HIV/AIDS transmission. Local and uniform stability of the fractional order model is studied. The theoretical results are illustrated through numerical simulations.
Introduction. Can the infection due to the human immunodeficiency virus type 1 induce a change in the differentiation status or process in T cells?. Methods. We will consider two stochastic Markov chain models, one which will describe the…
We consider the classical Turing instability in a reaction-diffusion system as the secend part of our study on pattern formation. We prove that nonlinear dynamics of a general perturbation of the Turing instability is determined by the…
We consider the basic model of virus dynamics in the modeling of Human Immunodeficiency Virus (HIV), in a 2D heterogenous environment. It consists of two ODEs for the non-infected and infected $CD_4^+$ $T$ lymphocytes, $T$ and $I$, and a…
Crohn's disease is an inflammatory bowel disease (IBD) that is not well understood. In particular, unlike other IBDs, the inflamed parts of the intestine compromise deep layers of the tissue and are not continuous but separated and…