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Deep learning-based modeling of multimodal Electronic Health Records (EHRs) has become an important approach for clinical diagnosis and risk prediction. However, due to diverse clinical workflows and privacy constraints, raw EHRs are…

Machine Learning · Computer Science 2026-04-09 Bohao Li , Tao Zou , Junchen Ye , Yan Gong , Bowen Du

With the everlasting development of technology and society, data privacy has proven to grow into a pressing issue. The bureaucratic state system seems to expand the number of personal documents required for any kind of request. Therefore,…

Computers and Society · Computer Science 2018-10-01 Cristina Georgiana Calancea , Lenuta Alboaie , Andrei Panu

To derive valuable insights from statistics, machine learning applications frequently analyze substantial amounts of data. In this work, we address the problem of designing efficient secure techniques to probe large datasets which allow a…

Cryptography and Security · Computer Science 2024-12-19 Malika Izabachène , Jean-Philippe Bossuat

Scientific data management is at a critical juncture, driven by exponential data growth, increasing cross-domain dependencies, and a severe reproducibility crisis in modern research. Traditional centralized data management approaches are…

Databases · Computer Science 2025-04-30 Sebastian Beyvers , Jannis Hochmuth , Lukas Brehm , Maria Hansen , Alexander Goesmann , Frank Förster

Multisite medical data sharing is critical in modern clinical practice and medical research. The challenge is to conduct data sharing that preserves individual privacy and data usability. The shortcomings of traditional privacy-enhancing…

Colorectal cancer (CRC) grading is a critical prognostic factor but remains hampered by inter-observer variability and the privacy constraints of multi-institutional data sharing. While deep learning offers a path to automation, centralized…

The increasing adoption of digital health technologies has amplified the need for robust, interoperable solutions to manage complex healthcare data. We present the Spezi Data Pipeline, an open-source Python toolkit designed to streamline…

The proliferation of sensor technologies and advancements in data collection methods have enabled the accumulation of very large amounts of data. Increasingly, these datasets are considered for scientific research. However, the design of…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-28 Fatemeh Rouzbeh , Ananth Grama , Paul Griffin , Mohammad Adibuzzaman

Consent is an ethical cornerstone of clinical research and healthcare in general. Although the ethical principles of consent - providing information, ensuring comprehension, and ensuring voluntariness - are well-defined, the technological…

Cryptography and Security · Computer Science 2026-02-04 Montassar Naghmouchi , Maryline Laurent

Data sharing barriers are paramount challenges arising from multicenter clinical studies where multiple data sources are stored in a distributed fashion at different local study sites. Particularly in the case of time-to-event analysis when…

Applications · Statistics 2024-09-10 Mengtong Hu , Xu Shi , Peter X. -K. Song

Electronic Health Records (EHRs) and Medical Data are classified as personal data in every privacy law, meaning that any related service that includes processing such data must come with full security, confidentiality, privacy and…

Cryptography and Security · Computer Science 2024-08-01 Marie Tcholakian , Karolina Gorna , Maryline Laurent , Hella Kaffel Ben Ayed , Montassar Naghmouchi

Centralized electronic health record repositories are critical for advancing disease surveillance, public health research, and evidence-based policymaking. However, developing countries face persistent challenges in achieving this due to…

This paper presents a data-centric and security-focused data fabric designed for digital health applications. With the increasing interest in digital health research, there has been a surge in the volume of Internet of Things (IoT) data…

As Large Language Model (LLM) agents transition from single-session tools to persistent systems managing longitudinal healthcare journeys, their memory architectures face a critical challenge: reconciling two imperfect sources of truth. The…

Machine Learning · Computer Science 2026-05-01 Samuel L Pugh , Eric Yang , Alexander Muir Sutherland , Alessandra Breschi

In recent years, many researchers have focused on developing a feasible solution for storing and exchanging medical images in the field of health care. Current practices are deployed on cloud-based centralized data centers, which increase…

Cryptography and Security · Computer Science 2021-01-01 Mohamed Yaseen Jabarulla , Heung-No Lee

The Internet-of-Things (IoT) is an imminent and corporal technology that enables the connectivity of smart physical devices with virtual objects contriving in distinct platforms with the help of the internet. The IoT is under massive…

Cryptography and Security · Computer Science 2023-04-28 Asad Aftab , Chrysostomos Chrysostomou , Hassaan Khaliq Qureshi , Semeen Rehman

This study introduces RelCAT (Relation Concept Annotation Toolkit), an interactive tool, library, and workflow designed to classify relations between entities extracted from clinical narratives. Building upon the CogStack MedCAT framework,…

Computation and Language · Computer Science 2025-01-28 Shubham Agarwal , Vlad Dinu , Thomas Searle , Mart Ratas , Anthony Shek , Dan F. Stein , James Teo , Richard Dobson

The digitization of medical records ushered in a new era of big data to clinical science, and with it the possibility that data could be shared, to multiply insights beyond what investigators could abstract from paper records. The need to…

Machine Learning · Computer Science 2021-06-03 Ofer Mendelevitch , Michael D. Lesh

Medical image classification plays a crucial role in computer-aided clinical diagnosis. While deep learning techniques have significantly enhanced efficiency and reduced costs, the privacy-sensitive nature of medical imaging data…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Sufen Ren , Yule Hu , Shengchao Chen , Guanjun Wang

Objectives: We propose a novel imputation method tailored for Electronic Health Records (EHRs) with structured and sporadic missingness. Such missingness frequently arises in the integration of heterogeneous EHR datasets for downstream…

Applications · Statistics 2025-10-13 Jianbin Tan , Yan Zhang , Chuan Hong , T. Tony Cai , Tianxi Cai , Anru R. Zhang
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