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The trade-off between predictive accuracy and data availability makes it difficult to predict protein--protein binding affinity accurately. The lack of experimentally resolved protein structures limits the performance of structure-based…

Machine Learning · Computer Science 2026-01-08 Wajid Arshad Abbasi , Syed Ali Abbas , Maryum Bibi , Saiqa Andleeb , Muhammad Naveed Akhtar

Knowledge distillation is a widely applicable technique for training a student neural network under the guidance of a trained teacher network. For example, in neural network compression, a high-capacity teacher is distilled to train a…

Computer Vision and Pattern Recognition · Computer Science 2019-08-05 Frederick Tung , Greg Mori

This paper explores the use of knowledge distillation to improve a Multi-Task Deep Neural Network (MT-DNN) (Liu et al., 2019) for learning text representations across multiple natural language understanding tasks. Although ensemble learning…

Computation and Language · Computer Science 2019-04-23 Xiaodong Liu , Pengcheng He , Weizhu Chen , Jianfeng Gao

In self-supervised learning, self-distilled methods have shown impressive performance, learning representations useful for downstream tasks and even displaying emergent properties. However, state-of-the-art methods usually rely on ensembles…

Machine Learning · Computer Science 2026-05-01 Esteban Rodríguez-Betancourt , Edgar Casasola-Murillo

While deep models have proved successful in learning rich knowledge from massive well-annotated data, they may pose a privacy leakage risk in practical deployment. It is necessary to find an effective trade-off between high utility and…

Machine Learning · Computer Science 2024-09-05 Shiming Ge , Bochao Liu , Pengju Wang , Yong Li , Dan Zeng

Distillation with unlabeled examples is a popular and powerful method for training deep neural networks in settings where the amount of labeled data is limited: A large ''teacher'' neural network is trained on the labeled data available,…

Machine Learning · Computer Science 2022-10-14 Fotis Iliopoulos , Vasilis Kontonis , Cenk Baykal , Gaurav Menghani , Khoa Trinh , Erik Vee

End-to-end training with back propagation is the standard method for training deep neural networks. However, as networks become deeper and bigger, end-to-end training becomes more challenging: highly non-convex models gets stuck easily in…

Machine Learning · Computer Science 2020-10-12 Laëtitia Shao , Max Moroz , Elad Eban , Yair Movshovitz-Attias

Topic models are often used to identify human-interpretable topics to help make sense of large document collections. We use knowledge distillation to combine the best attributes of probabilistic topic models and pretrained transformers. Our…

Computation and Language · Computer Science 2020-10-07 Alexander Hoyle , Pranav Goel , Philip Resnik

An activation boundary for a neuron refers to a separating hyperplane that determines whether the neuron is activated or deactivated. It has been long considered in neural networks that the activations of neurons, rather than their exact…

Machine Learning · Computer Science 2018-12-17 Byeongho Heo , Minsik Lee , Sangdoo Yun , Jin Young Choi

Knowledge distillation is often used to transfer knowledge from a strong teacher model to a relatively weak student model. Traditional methods include response-based methods and feature-based methods. Response-based methods are widely used…

Information Retrieval · Computer Science 2023-12-12 Hao Sun , Xiao Liu , Yeyun Gong , Anlei Dong , Jingwen Lu , Yan Zhang , Linjun Yang , Rangan Majumder , Nan Duan

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

Neurons and Cognition · Quantitative Biology 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

In natural language processing (NLP) tasks, slow inference speed and huge footprints in GPU usage remain the bottleneck of applying pre-trained deep models in production. As a popular method for model compression, knowledge distillation…

Computation and Language · Computer Science 2020-12-15 Fei Yuan , Linjun Shou , Jian Pei , Wutao Lin , Ming Gong , Yan Fu , Daxin Jiang

Convolutional neural networks have been widely deployed in various application scenarios. In order to extend the applications' boundaries to some accuracy-crucial domains, researchers have been investigating approaches to boost accuracy…

Machine Learning · Computer Science 2019-05-21 Linfeng Zhang , Jiebo Song , Anni Gao , Jingwei Chen , Chenglong Bao , Kaisheng Ma

Pruning aims to reduce the number of parameters while maintaining performance close to the original network. This work proposes a novel \emph{self-distillation} based pruning strategy, whereby the representational similarity between the…

Machine Learning · Computer Science 2021-10-01 James O' Neill , Sourav Dutta , Haytham Assem

Large Language Models (LLMs) have exhibited impressive capabilities in various tasks, yet their vast parameter sizes restrict their applicability in resource-constrained settings. Knowledge distillation (KD) offers a viable solution by…

Computation and Language · Computer Science 2024-06-07 Rongzhi Zhang , Jiaming Shen , Tianqi Liu , Haorui Wang , Zhen Qin , Feng Han , Jialu Liu , Simon Baumgartner , Michael Bendersky , Chao Zhang

Knowledge distillation (KD), a technique widely employed in computer vision, has emerged as a de facto standard for improving the performance of small neural networks. However, prevailing KD-based approaches in video tasks primarily focus…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Guiqin Wang , Peng Zhao , Yanjiang Shi , Cong Zhao , Shusen Yang

Computational pathology models rarely utilise data that will not be available for inference. This means most models cannot learn from highly informative data such as additional immunohistochemical (IHC) stains and spatial transcriptomics.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Lucas Farndale , Robert Insall , Ke Yuan

The rise of deep learning has greatly advanced human behavior monitoring using wearable sensors, particularly human activity recognition (HAR). While deep models have been widely studied, most assume stationary data distributions - an…

Knowledge distillation is a strategy of training a student network with guide of the soft output from a teacher network. It has been a successful method of model compression and knowledge transfer. However, currently knowledge distillation…

Machine Learning · Computer Science 2024-10-21 Guangda Ji , Zhanxing Zhu

Many natural language processing tasks can be modeled into structured prediction and solved as a search problem. In this paper, we distill an ensemble of multiple models trained with different initialization into a single model. In addition…

Computation and Language · Computer Science 2018-05-30 Yijia Liu , Wanxiang Che , Huaipeng Zhao , Bing Qin , Ting Liu