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Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Computation and Language · Computer Science 2025-03-25 Nicholas Wan , Qiao Jin , Joey Chan , Guangzhi Xiong , Serina Applebaum , Aidan Gilson , Reid McMurry , R. Andrew Taylor , Aidong Zhang , Qingyu Chen , Zhiyong Lu

Clinical calculators play a vital role in healthcare by offering accurate evidence-based predictions for various purposes such as prognosis. Nevertheless, their widespread utilization is frequently hindered by usability challenges, poor…

Computation and Language · Computer Science 2024-02-21 Qiao Jin , Zhizheng Wang , Yifan Yang , Qingqing Zhu , Donald Wright , Thomas Huang , W John Wilbur , Zhe He , Andrew Taylor , Qingyu Chen , Zhiyong Lu

Multi-Modal Large Language Models (MLLMs), despite being successful, exhibit limited generality and often fall short when compared to specialized models. Recently, LLM-based agents have been developed to address these challenges by…

Computation and Language · Computer Science 2024-10-08 Binxu Li , Tiankai Yan , Yuanting Pan , Jie Luo , Ruiyang Ji , Jiayuan Ding , Zhe Xu , Shilong Liu , Haoyu Dong , Zihao Lin , Yixin Wang

Large Language Models (LLMs) achieve competitive results compared to human experts in medical examinations. However, it remains a challenge to apply LLMs to complex clinical decision-making, which requires a deep understanding of medical…

Large language models (LLMs) combined with tool learning have gained impressive results in real-world applications. During tool learning, LLMs may call multiple tools in nested orders, where the latter tool call may take the former response…

Computation and Language · Computer Science 2025-01-08 Han Han , Tong Zhu , Xiang Zhang , Mengsong Wu , Hao Xiong , Wenliang Chen

Tool learning is increasingly important for large language models (LLMs) to effectively coordinate and utilize a diverse set of tools in order to solve complex real-world tasks. By selecting and integrating appropriate tools, LLMs extend…

Machine Learning · Computer Science 2026-01-21 Zheng Fang , Wolfgang Mayer , Zeyu Zhang , Jian Wang , Hong-Yu Zhang , Wanli Li , Zaiwen Feng

As opposed to evaluating computation and logic-based reasoning, current benchmarks for evaluating large language models (LLMs) in medicine are primarily focused on question-answering involving domain knowledge and descriptive reasoning.…

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

The rapid advancement of Large Language Models (LLMs) has stimulated interest in multi-agent collaboration for addressing complex medical tasks. However, the practical advantages of multi-agent collaboration approaches remain insufficiently…

Artificial Intelligence · Computer Science 2025-10-31 Yinghao Zhu , Ziyi He , Haoran Hu , Xiaochen Zheng , Xichen Zhang , Zixiang Wang , Junyi Gao , Liantao Ma , Lequan Yu

LLMs have achieved significant performance progress in various NLP applications. However, LLMs still struggle to meet the strict requirements for accuracy and reliability in the medical field and face many challenges in clinical…

Computation and Language · Computer Science 2024-10-11 Weixiang Yan , Haitian Liu , Tengxiao Wu , Qian Chen , Wen Wang , Haoyuan Chai , Jiayi Wang , Weishan Zhao , Yixin Zhang , Renjun Zhang , Li Zhu , Xuandong Zhao

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Large Language Models (LLMs) have shown promising potential in the medical domain, assisting with tasks like clinical note generation and patient communication. However, current LLMs are limited to text-based communication, hindering their…

Computation and Language · Computer Science 2025-06-17 Yusheng Liao , Shuyang Jiang , Yanfeng Wang , Yu Wang

Personalized digital health support requires long-horizon, cross-dimensional reasoning over heterogeneous lifestyle signals, and recent advances in mobile sensing and large language models (LLMs) make such support increasingly feasible.…

Artificial Intelligence · Computer Science 2026-01-21 Ye Tian , Zihao Wang , Onat Gungor , Xiaoran Fan , Tajana Rosing

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Medical calculators are fundamental to quantitative, evidence-based clinical practice. However, their real-world use is an adaptive, multi-stage process, requiring proactive EHR data acquisition, scenario-dependent calculator selection, and…

Artificial Intelligence · Computer Science 2026-02-02 Yakun Zhu , Yutong Huang , Shengqian Qin , Zhongzhen Huang , Shaoting Zhang , Xiaofan Zhang

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

With the remarkable advancements of large language models (LLMs), LLM-based agents have become a research hotspot in human-computer interaction. However, there is a scarcity of benchmarks available for LLM-based mobile agents. Benchmarking…

Artificial Intelligence · Computer Science 2024-07-02 Shihan Deng , Weikai Xu , Hongda Sun , Wei Liu , Tao Tan , Jianfeng Liu , Ang Li , Jian Luan , Bin Wang , Rui Yan , Shuo Shang

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang
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