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Related papers: MedINST: Meta Dataset of Biomedical Instructions

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Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

MLLMs have recently become a focal point in the field of artificial intelligence research. Building on the strong capabilities of LLMs, MLLMs are adept at addressing complex multi-modal tasks. With the release of GPT-4, MLLMs have gained…

Machine Learning · Computer Science 2025-05-01 Jiarui Ye , Hao Tang

Tool learning is increasingly important for large language models (LLMs) to effectively coordinate and utilize a diverse set of tools in order to solve complex real-world tasks. By selecting and integrating appropriate tools, LLMs extend…

Machine Learning · Computer Science 2026-01-21 Zheng Fang , Wolfgang Mayer , Zeyu Zhang , Jian Wang , Hong-Yu Zhang , Wanli Li , Zaiwen Feng

Large Language Models are traditionally finetuned on large instruction datasets. However recent studies suggest that small, high-quality datasets can suffice for general purpose instruction following. This lack of consensus surrounding…

Machine Learning · Computer Science 2023-12-29 Aditi Jha , Sam Havens , Jeremy Dohmann , Alex Trott , Jacob Portes

We introduce MedAgentGym, a scalable and interactive training environment designed to enhance coding-based biomedical reasoning capabilities in large language model (LLM) agents. MedAgentGym comprises 72,413 task instances across 129…

Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address…

Computation and Language · Computer Science 2023-10-24 Junling Liu , Peilin Zhou , Yining Hua , Dading Chong , Zhongyu Tian , Andrew Liu , Helin Wang , Chenyu You , Zhenhua Guo , Lei Zhu , Michael Lingzhi Li

Recently, the impressive performance of large language models (LLMs) on a wide range of tasks has attracted an increasing number of attempts to apply LLMs in drug discovery. However, molecule optimization, a critical task in the drug…

Quantitative Methods · Quantitative Biology 2024-01-22 Geyan Ye , Xibao Cai , Houtim Lai , Xing Wang , Junhong Huang , Longyue Wang , Wei Liu , Xiangxiang Zeng

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Single-task models have proven pivotal in solving specific tasks; however, they have limitations in real-world applications where multi-tasking is necessary and domain shifts are exhibited. Recently, instructional prompts have shown…

Computation and Language · Computer Science 2022-04-19 Mihir Parmar , Swaroop Mishra , Mirali Purohit , Man Luo , M. Hassan Murad , Chitta Baral

In this paper, we introduce the MLM (Multiple Languages and Modalities) dataset - a new resource to train and evaluate multitask systems on samples in multiple modalities and three languages. The generation process and inclusion of semantic…

Machine Learning · Computer Science 2020-10-27 Jason Armitage , Endri Kacupaj , Golsa Tahmasebzadeh , Swati , Maria Maleshkova , Ralph Ewerth , Jens Lehmann

Understanding 3D medical image volumes is a critical task in the medical domain. However, existing 3D convolution and transformer-based methods have limited semantic understanding of an image volume and also need a large set of volumes for…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Qiuhui Chen , Huping Ye , Yi Hong

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Large language models (LLMs) with extended context windows enable tasks requiring extensive information integration but are limited by the scarcity of high-quality, diverse datasets for long-context instruction tuning. Existing data…

Computation and Language · Computer Science 2025-02-25 Jiaxi Li , Xingxing Zhang , Xun Wang , Xiaolong Huang , Li Dong , Liang Wang , Si-Qing Chen , Wei Lu , Furu Wei

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Large Language Models (LLMs) demonstrate strong performance in real-world applications, yet existing open-source instruction datasets often concentrate on narrow domains, such as mathematics or coding, limiting generalization and widening…

Computation and Language · Computer Science 2025-06-16 Jijie Li , Li Du , Hanyu Zhao , Bo-wen Zhang , Liangdong Wang , Boyan Gao , Guang Liu , Yonghua Lin

With the rapid development of large language models (LLMs) and their integration into large multimodal models (LMMs), there has been impressive progress in zero-shot completion of user-oriented vision-language tasks. However, a gap remains…

Computation and Language · Computer Science 2024-04-16 Fuxiao Liu , Xiaoyang Wang , Wenlin Yao , Jianshu Chen , Kaiqiang Song , Sangwoo Cho , Yaser Yacoob , Dong Yu

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Artificial Intelligence · Computer Science 2025-12-17 Zifeng Wang , Jiacheng Lin , Qiao Jin , Junyi Gao , Jathurshan Pradeepkumar , Pengcheng Jiang , Zhiyong Lu , Jimeng Sun

Medical decision-support and advising systems are critical for emergency physicians to quickly and accurately assess patients' conditions and make diagnosis. Artificial Intelligence (AI) has emerged as a transformative force in healthcare…

Large Language Models (LLMs) have shown remarkable capabilities, with optimizing their input prompts playing a pivotal role in maximizing their performance. However, while LLM prompts consist of both the task-agnostic system prompts and…

Computation and Language · Computer Science 2025-10-13 Yumin Choi , Jinheon Baek , Sung Ju Hwang
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