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Cell growth in size is a complex process coordinated by intrinsic and environmental signals. In a recent work [Tzur et al., Science, 2009, 325:167-171], size distributions in an exponentially growing population of mammalian cells were used…

Cell Behavior · Quantitative Biology 2015-06-16 Yucheng Hu , Tianqi Zhu

We provide a numerical study of the macroscopic model of [3] derived from an agent-based model for a system of particles interacting through a dynamical network of links. Assuming that the network remodelling process is very fast, the…

We introduce and discuss a kinetic framework describing the time evolution of the statistical distributions of a population divided into the compartments of susceptible, infectious, recovered, and resistant in the presence of a microbial…

Populations and Evolution · Quantitative Biology 2026-05-07 Marco Menale , Giuseppe Toscani , Mattia Zanella

This article is a presentation of specific recent results describing scaling limits of individual-based models. Thanks to them, we wish to relate the time-scales typical of demographic dynamics and natural selection to the parameters of the…

Probability · Mathematics 2023-08-01 Aurélien Velleret

We consider a noninteracting disordered system designed to model particle diffusion, relaxation in glasses, and impurity bands of semiconductors. Disorder originates in the random spatial distribution of sites. We find strong numerical…

Disordered Systems and Neural Networks · Physics 2015-03-17 Jacob J. Krich , Alán Aspuru-Guzik

We analyze the coalescing model where a `primary' colony grows and randomly emits secondary colonies that spread and eventually coalesce with it. This model describes population proliferation in theoretical ecology, tumor growth and is also…

Populations and Evolution · Quantitative Biology 2018-01-03 Giulia Carra , Kirone Mallick , Marc Barthelemy

How do competing populations convert a spatial advantage into macroscopic dominance? We introduce a stochastic model for resource competition that decouples the transient discovery phase from monopolization. Initial symmetry breaking is…

Populations and Evolution · Quantitative Biology 2026-03-12 Stuti Guha , Shawn D. Ryan , Bhargav R. Karamched

We take up the challenge of designing realistic computational models of large interacting cell populations. The goal is essentially to bring Gillespie's celebrated stochastic methodology to the level of an interacting population of cells.…

Computational Engineering, Finance, and Science · Computer Science 2018-10-26 Stefan Engblom

Discrete time, spatially extended models play an important role in ecology, modelling population dynamics of species ranging from micro-organisms to birds. An important question is how 'bottom up', individual-based models can be…

Populations and Evolution · Quantitative Biology 2023-01-20 Linnéa Gyllingberg , David J. T. Sumpter , Åke Brännström

Multiscale models allow for the treatment of complex phenomena involving different scales, such as remodeling and growth of tissues, muscular activation, and cardiac electrophysiology. Numerous numerical approaches have been developed to…

Numerical Analysis · Mathematics 2018-06-28 Marco Favino , Alessio Quaglino , Sonia Pozzi , Rolf Krause , Igor Pivkin

We prove pathwise convergence of the layerwise evolution of tokens in a finite-depth, finite-width transformer model with MultiLayer Perceptron (MLP) blocks to a continuous-time stochastic interacting particle system. We also identify the…

Probability · Mathematics 2026-04-30 Andrea Agazzi , Giuseppe Bruno , Eloy Mosig García , Samuele Saviozzi , Marco Romito

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

Large ensembles of stochastically evolving interacting particles describe phenomena in diverse fields including statistical physics, neuroscience, biology, and engineering. In such systems, the infinitesimal evolution of each particle…

Probability · Mathematics 2024-01-02 Kavita Ramanan

Markovian population models are suitable abstractions to describe well-mixed interacting particle systems in situation where stochastic fluctuations are significant due to the involvement of low copy particles. In molecular biology,…

Quantitative Methods · Quantitative Biology 2014-01-17 Christoph Zechner , Federico Wadehn , Heinz Koeppl

In this paper a new multiscale modeling technique is proposed. It relies on a recently introduced measure-theoretic approach, which allows to manage the microscopic and the macroscopic scale under a unique framework. In the resulting…

Mathematical Physics · Physics 2011-01-24 Emiliano Cristiani , Benedetto Piccoli , Andrea Tosin

In the development of multiscale biological models it is crucial to establish a connection between discrete microscopic or mesoscopic stochastic models and macroscopic continuous descriptions based on cellular density. In this paper a…

Biological Physics · Physics 2009-11-13 Mark Alber , Nan Chen , Pavel M. Lushnikov , Stuart A. Newman

Scaling limits of critical percolation models show major differences between low and high dimensional models. The article discusses the formulation of the continuum limit for the former case. A mathematical framework is proposed for the…

Statistical Mechanics · Physics 2009-09-25 Michael Aizenman

The goal of this paper is to describe the various kinetic equations which arise from scaling limits of interacting particle systems. We provide a formalism which allows us to determine the kinetic equation for a given interaction potential…

Mathematical Physics · Physics 2020-12-10 Alessia Nota , Juan J. L. Velázquez , Raphael Winter

We consider a discrete-time model for random interface growth which admits exact formulas and converges to the Polynuclear growth model in a particular limit. The height of the interface is initially flat and the evolution involves the…

Probability · Mathematics 2023-08-28 Will FitzGerald

Based on the proposed earlier by the Author approach to macroscopic description of scalar interaction, this paper develops the macroscopic model of relativistic plasma with a fantom scalar interaction of elementary particles. In the article…

General Relativity and Quantum Cosmology · Physics 2015-06-22 Yu. G. Ignatyev , A. A. Agathonov , D. Yu. Ignatyev