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Osteosarcoma is the most common malignant primary bone tumor. Standard treatment includes pre-operative chemotherapy followed by surgical resection. The response to treatment as measured by ratio of necrotic tumor area to overall tumor area…

Semantic segmentation under domain shift remains a fundamental challenge in computer vision, particularly when labelled training data is scarce. This challenge is particularly exemplified in histopathology image analysis, where the same…

Lesion segmentation is an important problem in computer-assisted diagnosis that remains challenging due to the prevalence of low contrast, irregular boundaries that are unamenable to shape priors. We introduce Deep Active Lesion…

Osteoporosis is a common bone disease that occurs when the creation of new bone does not keep up with the loss of old bone, resulting in increased fracture risk. Adults over the age of 50 are especially at risk and see their quality of life…

The study objective was to investigate the performance of a dedicated convolutional neural network (CNN) optimized for wrist cartilage segmentation from 2D MR images. CNN utilized a planar architecture and patch-based (PB) training approach…

Accurate understanding of anatomical structures is essential for reliably staging certain dental diseases. A way of introducing this within semantic segmentation models is by utilising hierarchy-aware methodologies. However, existing…

Automated clinical decision support for clear aligner orthodontics faces a key challenge: bridging geometric perception (3D tooth segmentation) with clinical reasoning (biomechanical feasibility). We address this with OrthOAI, introducing…

Skeletal bone age assessment is a common clinical practice to diagnose endocrine and metabolic disorders in child development. In this paper, we describe a fully automated deep learning approach to the problem of bone age assessment using…

Accurate segmentation of carotid artery structures in histopathological images is vital for cardiovascular disease research. This study systematically evaluates ten deep learning segmentation models including classical architectures, modern…

At present, decision making solutions developed based on deep learning (DL) models have received extensive attention in predictive maintenance (PM) applications along with the rapid improvement of computing power. Relying on the superior…

With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagno- sis, and medical intervention. Since manual anno- tation su ers limited…

Continual learning protocols are attracting increasing attention from the medical imaging community. In continual environments, datasets acquired under different conditions arrive sequentially; and each is only available for a limited…

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Brain tissue segmentation from multimodal MRI is a key building block of many neuroimaging analysis pipelines. Established tissue segmentation approaches have, however, not been developed to cope with large anatomical changes resulting from…

Objective assessment of Magnetic Resonance Imaging (MRI) scans of osteoarthritis (OA) can address the limitation of the current OA assessment. Segmentation of bone, cartilage, and joint fluid is necessary for the OA objective assessment.…

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Histopathologic diagnosis relies on simultaneous integration of information from a broad range of scales, ranging from nuclear aberrations ($\approx \mathcal{O}(0.1{\mu m})$) through cellular structures ($\approx \mathcal{O}(10{\mu m})$) to…

In clinical practice, medical segmentation datasets are often limited and heterogeneous, with variations in modalities, protocols, and anatomical targets across institutions. Existing deep learning models struggle to jointly learn from such…

Semantic segmentation of breast cancer metastases in histopathological slides is a challenging task. In fact, significant variation in data characteristics of histopathology images (domain shift) make generalization of deep learning to…