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Large language models (LLMs) have demonstrated remarkable performance on various medical benchmarks, but their capabilities across different cognitive levels remain underexplored. Inspired by Bloom's Taxonomy, we propose a…

Computation and Language · Computer Science 2025-06-11 Yuxuan Zhou , Xien Liu , Chenwei Yan , Chen Ning , Xiao Zhang , Boxun Li , Xiangling Fu , Shijin Wang , Guoping Hu , Yu Wang , Ji Wu

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Knowledge sharing is crucial in healthcare, especially when leveraging data from multiple clinical sites to address data scarcity, reduce costs, and enable timely interventions. Transfer learning can facilitate cross-site knowledge…

Computation and Language · Computer Science 2024-09-24 Yuhe Gao , Runxue Bao , Yuelyu Ji , Yiming Sun , Chenxi Song , Jeffrey P. Ferraro , Ye Ye

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency…

Computation and Language · Computer Science 2025-01-07 Yiming Zhang , Zheng Chang , Wentao Cai , MengXing Ren , Kang Yuan , Yining Sun , Zenghui Ding

In this paper, we introduce InMD-X, a collection of multiple large language models specifically designed to cater to the unique characteristics and demands of Internal Medicine Doctors (IMD). InMD-X represents a groundbreaking development…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Hansle Gwon , Imjin Ahn , Hyoje Jung , Byeolhee Kim , Young-Hak Kim , Tae Joon Jun

Large Language Models (LLMs) represent a class of deep learning models adept at understanding natural language and generating coherent responses to various prompts or queries. These models far exceed the complexity of conventional neural…

Machine Learning · Computer Science 2024-12-05 Minghao Shao , Abdul Basit , Ramesh Karri , Muhammad Shafique

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured…

Computation and Language · Computer Science 2026-04-21 Arya Hadizadeh Moghaddam , Drew Ross , Mohsen Nayebi Kerdabadi , Dongjie Wang , Zijun Yao

Identifying disease interconnections through manual analysis of large-scale clinical data is labor-intensive, subjective, and prone to expert disagreement. While machine learning (ML) shows promise, three critical challenges remain: (1)…

Medical concept extraction from electronic health records underpins many downstream applications, yet remains challenging because medically meaningful concepts are frequently implied rather than explicitly stated in medical narratives.…

Computation and Language · Computer Science 2026-05-21 Zhichao Yang , Gregory D. Lyng , Sanjit Singh Batra , Robert E. Tillman

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

Large language models (LLMs) have been applied to tasks in healthcare, ranging from medical exam questions to responding to patient questions. With increasing institutional partnerships between companies producing LLMs and healthcare…

Computation and Language · Computer Science 2024-04-10 Jesutofunmi A. Omiye , Haiwen Gui , Shawheen J. Rezaei , James Zou , Roxana Daneshjou

Recently, large language model (LLM) based artificial intelligence (AI) systems have demonstrated remarkable capabilities in natural language understanding and generation. However, these models face a significant challenge when it comes to…

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Chronic diseases such as diabetes are the leading causes of morbidity and mortality worldwide. Numerous research studies have been attempted with various deep learning models in diagnosis. However, most previous studies had certain…

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Large Language Models (LLMs) have become a pivotal research area, potentially making beneficial contributions in fields like healthcare where they can streamline automated billing and decision support. However, the frequent use of…

Computation and Language · Computer Science 2024-06-10 Simon A. Lee , Timothy Lindsey

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Large Language Models (LLMs) have demonstrated remarkable versatility in recent years, offering potential applications across specialized domains such as healthcare and medicine. Despite the availability of various open-source LLMs tailored…

Computation and Language · Computer Science 2024-07-18 Yanis Labrak , Adrien Bazoge , Emmanuel Morin , Pierre-Antoine Gourraud , Mickael Rouvier , Richard Dufour
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