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Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Acquiring and annotating surgical data is often resource-intensive, ethical constraining, and requiring significant expert involvement. While generative AI models like text-to-image can alleviate data scarcity, incorporating spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Aditya Bhat , Rupak Bose , Chinedu Innocent Nwoye , Nicolas Padoy

Deep neural networks have been extensively applied in the medical domain for various tasks, including image classification, segmentation, and landmark detection. However, their application is often hindered by data scarcity, both in terms…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Roberto Di Via , Francesca Odone , Vito Paolo Pastore

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Generative latent diffusion models have been established as state-of-the-art in data generation. One promising application is generation of realistic synthetic medical imaging data for open data sharing without compromising patient privacy.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Salman Ul Hassan Dar , Arman Ghanaat , Jannik Kahmann , Isabelle Ayx , Theano Papavassiliu , Stefan O. Schoenberg , Sandy Engelhardt

Patients undergoing a mechanical thrombectomy procedure usually have a multi-detector CT (MDCT) scan before and after the intervention. The image quality of the flat panel detector CT (FDCT) present in the intervention room is generally…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Hélène Corbaz , Anh Nguyen , Victor Schulze-Zachau , Paul Friedrich , Alicia Durrer , Florentin Bieder , Philippe C. Cattin , Marios N Psychogios

One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Steve Kommrusch , Louis-Noël Pouchet

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Denoising Diffusion Models (DDMs) are widely used for high-quality image generation and medical image segmentation but often rely on Unet-based architectures, leading to high computational overhead, especially with high-resolution images.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Avni Mittal , John Kalkhof , Anirban Mukhopadhyay , Arnav Bhavsar

Deep learning models in medical contexts face challenges like data scarcity, inhomogeneity, and privacy concerns. This study focuses on improving ventricular segmentation in brain MRI images using synthetic data. We employed two latent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Tim Ruschke , Jonathan Frederik Carlsen , Adam Espe Hansen , Ulrich Lindberg , Amalie Monberg Hindsholm , Martin Norgaard , Claes Nøhr Ladefoged

Denoising Probabilistic Models (DPMs) represent an emerging domain of generative models that excel in generating diverse and high-quality images. However, most current training methods for DPMs often neglect the correlation between…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Viet Nguyen , Giang Vu , Tung Nguyen Thanh , Khoat Than , Toan Tran

This study explores the generation of synthesized fingerprint images using Denoising Diffusion Probabilistic Models (DDPMs). The significant obstacles in collecting real biometric data, such as privacy concerns and the demand for diverse…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Freddie Grabovski , Lior Yasur , Yaniv Hacmon , Lior Nisimov , Stav Nimrod

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Marvin Seyfarth , Salman Ul Hassan Dar , Isabelle Ayx , Matthias Alexander Fink , Stefan O. Schoenberg , Hans-Ulrich Kauczor , Sandy Engelhardt

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Reducing the radiation dose in computed tomography (CT) is important to mitigate radiation-induced risks. One option is to employ a well-trained model to compensate for incomplete information and map sparse-view measurements to the CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Xiaoyue Li , Kai Shang , Gaoang Wang , Mark D. Butala

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Ultra-high resolution images are desirable in photon counting CT (PCCT), but resolution is physically limited by interactions such as charge sharing. Deep learning is a possible method for super-resolution (SR), but sourcing paired training…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Christopher Wiedeman , Chuang Niu , Mengzhou Li , Bruno De Man , Jonathan S Maltz , Ge Wang
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