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Uncovering the underlying causal mechanisms of complex real-world systems remains a significant challenge, as these systems often entail high data collection costs and involve unknown interventions. We introduce MetaCaDI, the first…

Machine Learning · Statistics 2025-10-28 Hans Jarett Ong , Yoichi Chikahara , Tomoharu Iwata

Recent developments in structural equation modeling have produced several methods that can usually distinguish cause from effect in the two-variable case. For that purpose, however, one has to impose substantial structural constraints or…

Artificial Intelligence · Computer Science 2015-04-23 Kun Zhang , Jiji Zhang , Bernhard Schölkopf

We consider the problem of estimating causal DAG models from a mix of observational and interventional data, when the intervention targets are partially or completely unknown. This problem is highly relevant for example in genomics, since…

Methodology · Statistics 2020-06-23 Chandler Squires , Yuhao Wang , Caroline Uhler

Real-world problems, for example in climate applications, often require causal reasoning on spatially gridded time series data or data with comparable structure. While the underlying system is often believed to behave similarly at different…

Machine Learning · Computer Science 2026-02-16 Martin Rabel , Jakob Runge

In many real-world scenarios, such as gene knockout experiments, targeted interventions are often accompanied by unknown interventions at off-target sites. Moreover, different units can get randomly exposed to different unknown…

Machine Learning · Statistics 2022-10-10 Abhinav Kumar , Gaurav Sinha

This article proposes a novel causal discovery and inference method called GrIVET for a Gaussian directed acyclic graph with unmeasured confounders. GrIVET consists of an order-based causal discovery method and a likelihood-based…

Methodology · Statistics 2023-09-22 Li Chen , Chunlin Li , Xiaotong Shen , Wei Pan

Causal discovery from observational data holds great promise, but existing methods rely on strong assumptions about the underlying causal structure, often requiring full observability of all relevant variables. We tackle these challenges by…

Reconstructing the causal relationships behind the phenomena we observe is a fundamental challenge in all areas of science. Discovering causal relationships through experiments is often infeasible, unethical, or expensive in complex…

Machine Learning · Statistics 2022-09-09 Christian Reiser

Causal structure discovery from observational data is fundamental to the causal understanding of autonomous systems such as medical decision support systems, advertising campaigns and self-driving cars. This is essential to solve well-known…

Learning DAG structures from purely observational data remains a long-standing challenge across scientific domains. An emerging line of research leverages the score of the data distribution to initially identify a topological order of the…

Machine Learning · Computer Science 2026-01-27 Vy Vo , He Zhao , Trung Le , Edwin V. Bonilla , Dinh Phung

We propose a method to classify the causal relationship between two discrete variables given only the joint distribution of the variables, acknowledging that the method is subject to an inherent baseline error. We assume that the causal…

Machine Learning · Statistics 2016-11-07 Krzysztof Chalupka , Frederick Eberhardt , Pietro Perona

Understanding the laws that govern a phenomenon is the core of scientific progress. This is especially true when the goal is to model the interplay between different aspects in a causal fashion. Indeed, causal inference itself is…

Artificial Intelligence · Computer Science 2025-08-27 Alessio Zanga , Elif Ozkirimli , Fabio Stella

Causal discovery, i.e., learning the causal graph from data, is often the first step toward the identification and estimation of causal effects, a key requirement in numerous scientific domains. Causal discovery is hampered by two main…

Machine Learning · Computer Science 2024-03-15 Ehsan Mokhtarian , Sepehr Elahi , Sina Akbari , Negar Kiyavash

Scientific discovery catalyzes human intellectual advances, driven by the cycle of hypothesis generation, experimental design, evaluation, and assumption refinement. Central to this process is causal inference, uncovering the mechanisms…

Machine Learning · Computer Science 2025-09-26 Ivaxi Sheth , Sahar Abdelnabi , Mario Fritz

Discovering the causal relationship via recovering the directed acyclic graph (DAG) structure from the observed data is a well-known challenging combinatorial problem. When there are latent variables, the problem becomes even more…

Machine Learning · Statistics 2023-11-02 Yunfeng Cai , Xu Li , Minging Sun , Ping Li

Understanding causal mechanisms across different populations is essential for designing effective public health interventions. Recently, difference graphs have been introduced as a tool to visually represent causal variations between two…

Artificial Intelligence · Computer Science 2025-02-18 Charles K. Assaad

In many problems, the measured variables (e.g., image pixels) are just mathematical functions of the latent causal variables (e.g., the underlying concepts or objects). For the purpose of making predictions in changing environments or…

Machine Learning · Computer Science 2024-08-13 Kun Zhang , Shaoan Xie , Ignavier Ng , Yujia Zheng

Learning a causal directed acyclic graph from data is a challenging task that involves solving a combinatorial problem for which the solution is not always identifiable. A new line of work reformulates this problem as a continuous…

Machine Learning · Computer Science 2020-11-05 Philippe Brouillard , Sébastien Lachapelle , Alexandre Lacoste , Simon Lacoste-Julien , Alexandre Drouin

Much of scientific data is collected as randomized experiments intervening on some and observing other variables of interest. Quite often, a given phenomenon is investigated in several studies, and different sets of variables are involved…

Methodology · Statistics 2012-10-19 Antti Hyttinen , Frederick Eberhardt , Patrik O. Hoyer

The estimation of heterogeneous treatment effects in the potential outcome setting is biased when there exists model misspecification or unobserved confounding. As these biases are unobservable, what model to use when remains a critical…

Methodology · Statistics 2024-05-09 Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn , Edoardo M. Airoldi
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