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The arc of drug discovery entails a multiparameter optimization problem spanning vast length scales. They key parameters range from solubility (angstroms) to protein-ligand binding (nanometers) to in vivo toxicity (meters). Through feature…

Most existing methods for predicting drug-drug interactions (DDI) predominantly concentrate on capturing the explicit relationships among drugs, overlooking the valuable implicit correlations present between drug pairs (DPs), which leads to…

Machine Learning · Computer Science 2024-02-29 Mengying Jiang , Guizhong Liu , Yuanchao Su , Weiqiang Jin , Biao Zhao

Multimodal models have been proven to outperform text-based models on learning semantic word representations. Almost all previous multimodal models typically treat the representations from different modalities equally. However, it is…

Computation and Language · Computer Science 2018-01-03 Shaonan Wang , Jiajun Zhang , Chengqing Zong

Molecular property prediction plays a fundamental role in drug discovery to identify candidate molecules with target properties. However, molecular property prediction is essentially a few-shot problem which makes it hard to use regular…

Machine Learning · Computer Science 2021-11-12 Yaqing Wang , Abulikemu Abuduweili , Quanming Yao , Dejing Dou

With the rapid advancements in wireless communication technology, automatic modulation recognition (AMR) plays a critical role in ensuring communication security and reliability. However, numerous challenges, including higher performance…

Machine Learning · Computer Science 2025-02-27 Dongwei Xu , Yutao Zhu , Yao Lu , Youpeng Feng , Yun Lin , Qi Xuan

Recent years have witnessed growing interests in multimedia recommendation, which aims to predict whether a user will interact with an item with multimodal contents. Previous studies focus on modeling user-item interactions with multimodal…

Information Retrieval · Computer Science 2022-03-18 Jinghao Zhang , Yanqiao Zhu , Qiang Liu , Mengqi Zhang , Shu Wu , Liang Wang

The limited extrapolative power of structure-based machine learning (ML) models is a critical bottleneck in chemical discovery, particularly for industrial R&D, where navigating uncharted chemical space to find next-generation materials or…

Polymers are high-molecular-weight compounds constructed by the covalent bonding of numerous identical or similar monomers so that their 3D structures are complex yet exhibit unignorable regularity. Typically, the properties of a polymer,…

Machine Learning · Computer Science 2024-07-29 Fanmeng Wang , Wentao Guo , Minjie Cheng , Shen Yuan , Hongteng Xu , Zhifeng Gao

In recent years, Deep Learning has been successfully applied to multimodal learning problems, with the aim of learning useful joint representations in data fusion applications. When the available modalities consist of time series data such…

Computer Vision and Pattern Recognition · Computer Science 2017-04-12 Xitong Yang , Palghat Ramesh , Radha Chitta , Sriganesh Madhvanath , Edgar A. Bernal , Jiebo Luo

Many sequential decision-making tasks involve optimizing multiple conflicting objectives, requiring policies that adapt to different user preferences. In multi-objective reinforcement learning (MORL), one widely studied approach} addresses…

Machine Learning · Computer Science 2026-04-28 Ying-Tu Chen , Wei Hung , Bing-Shu Wu , Zhang-Wei Hong , Ping-Chun Hsieh

While Multi-view Graph Neural Networks (MVGNNs) excel at leveraging diverse modalities for learning object representation, existing methods assume identical local topology structures across modalities that overlook real-world discrepancies.…

Machine Learning · Computer Science 2024-06-05 Peiyu Liang , Hongchang Gao , Xubin He

Deep neural networks show great potential for automating various visual quality inspection tasks in manufacturing. However, their applicability is limited in more volatile scenarios, such as remanufacturing, where the inspected products and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Johannes C. Bauer , Paul Geng , Stephan Trattnig , Petr Dokládal , Rüdiger Daub

Autonomous driving necessitates advanced object detection techniques that integrate information from multiple modalities to overcome the limitations associated with single-modal approaches. The challenges of aligning diverse data in early…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Qihang Yang , Yang Zhao , Hong Cheng

Recent advances in materials discovery have been driven by structure-based models, particularly those using crystal graphs. While effective for computational datasets, these models are impractical for real-world applications where atomic…

Machine Learning · Computer Science 2025-07-03 Jithendaraa Subramanian , Linda Hung , Daniel Schweigert , Santosh Suram , Weike Ye

Conventional multimodal recommender systems predominantly leverage Bayesian Personalized Ranking (BPR) optimization to learn item representations by amalgamating item identity (ID) embeddings with multimodal features. Nevertheless, our…

Information Retrieval · Computer Science 2025-05-09 Xin Zhou , Xiaoxiong Zhang , Dusit Niyato , Zhiqi Shen

We propose a compact and effective framework to fuse multimodal features at multiple layers in a single network. The framework consists of two innovative fusion schemes. Firstly, unlike existing multimodal methods that necessitate…

Computer Vision and Pattern Recognition · Computer Science 2021-08-12 Yikai Wang , Fuchun Sun , Ming Lu , Anbang Yao

Large Language Models (LLMs) often suffer from hallucinations, which Retrieval-Augmented Generation (RAG) and GraphRAG mitigate by incorporating external knowledge and knowledge graphs (KGs). However, GraphRAG remains text-centric due to…

Artificial Intelligence · Computer Science 2026-03-11 Xueyao Wan , Hang Yu

Artificial intelligence has demonstrated immense potential in scientific research. Within molecular science, it is revolutionizing the traditional computer-aided paradigm, ushering in a new era of deep learning. With recent progress in…

Biomolecules · Quantitative Biology 2024-03-22 Yi Xiao , Xiangxin Zhou , Qiang Liu , Liang Wang

Computational modeling of human multimodal language is an emerging research area in natural language processing spanning the language, visual and acoustic modalities. Comprehending multimodal language requires modeling not only the…

Machine Learning · Computer Science 2018-08-14 Paul Pu Liang , Ziyin Liu , Amir Zadeh , Louis-Philippe Morency

Multiresolution Matrix Factorization (MMF) is unusual amongst fast matrix factorization algorithms in that it does not make a low rank assumption. This makes MMF especially well suited to modeling certain types of graphs with complex…

Machine Learning · Computer Science 2024-08-20 Truong Son Hy , Thieu Khang , Risi Kondor
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