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Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

Semi-supervised learning is a model training method that uses both labeled and unlabeled data. This paper proposes a fully Bayes semi-supervised learning algorithm that can be applied to any multi-category classification problem. We assume…

Machine Learning · Statistics 2024-07-22 Rui Zhu , Shuvrarghya Ghosh , Subhashis Ghosal

Masked image modeling is a promising self-supervised learning method for visual data. It is typically built upon image patches with random masks, which largely ignores the variation of information density between them. The question is: Is…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Haijian Chen , Wendong Zhang , Yunbo Wang , Xiaokang Yang

In contrast to fully-supervised models, self-supervised representation learning only needs a fraction of data to be labeled and often achieves the same or even higher downstream performance. The goal is to pre-train deep neural networks on…

Machine Learning · Computer Science 2025-04-09 Friederike Baier , Sebastian Mair , Samuel G. Fadel

Auto-encoders are perhaps the best-known non-probabilistic methods for representation learning. They are conceptually simple and easy to train. Recent theoretical work has shed light on their ability to capture manifold structure, and drawn…

Machine Learning · Computer Science 2015-06-16 Daniel Jiwoong Im , Graham W. Taylor

Defining and separating cancer subtypes is essential for facilitating personalized therapy modality and prognosis of patients. The definition of subtypes has been constantly recalibrated as a result of our deepened understanding. During…

Machine Learning · Computer Science 2022-07-21 Zheng Chen , Ziwei Yang , Lingwei Zhu , Guang Shi , Kun Yue , Takashi Matsubara , Shigehiko Kanaya , MD Altaf-Ul-Amin

In the field of medical image segmentation, challenges such as indistinct lesion features, ambiguous boundaries,and multi-scale characteristics have long revailed. This paper proposes an improved method named Intensity-Spatial Dual Masked…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuexing Ding , Jun Wang , Hongbing Lyu

The coronavirus pandemic has been going on since the year 2019, and the trend is still not abating. Therefore, it is particularly important to classify medical CT scans to assist in medical diagnosis. At present, Supervised Deep Learning…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Jiashu Xu , Sergii Stirenko

Data labeling is often the most challenging task when developing computational pathology models. Pathologist participation is necessary to generate accurate labels, and the limitations on pathologist time and demand for large, labeled…

Quantitative Methods · Quantitative Biology 2021-11-12 Lantian Zhang , Mohamed Amgad , Lee A. D. Cooper

Self-supervised pre-training for images without labels has recently achieved promising performance in image classification. The success of transformer-based methods, ViT and MAE, draws the community's attention to the design of backbone…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Jiantao Wu , Shentong Mo

The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Masked Autoencoders (MAE) based on a reconstruction task have risen to be a promising paradigm for self-supervised learning (SSL) and achieve state-of-the-art performance across different benchmark datasets. However, despite its impressive…

Machine Learning · Computer Science 2023-03-28 Qi Zhang , Yifei Wang , Yisen Wang

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Masked Autoencoders (MAEs) have emerged as a powerful pretraining technique for vision foundation models. Despite their effectiveness, they require extensive hyperparameter tuning (masking ratio, patch size, encoder/decoder layers) when…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Anthony Bisulco , Rahul Ramesh , Randall Balestriero , Pratik Chaudhari

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

In this paper we propose a semi-supervised variational autoencoder for classification of overall survival groups from tumor segmentation masks. The model can use the output of any tumor segmentation algorithm, removing all assumptions on…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Sveinn Pálsson , Stefano Cerri , Andrea Dittadi , Koen Van Leemput