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Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

Methodology · Statistics 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

The spread of an infectious disease depends on intrinsic properties of the disease as well as the connectivity and actions of the population. This study investigates the dynamics of an SIR type model which accounts for human tendency to…

Dynamical Systems · Mathematics 2021-07-26 Hannah Scanlon , John Gemmer

Due to limitations such as geographic, physical, or economic factors, collected seismic data often have missing traces. Traditional seismic data reconstruction methods face the challenge of selecting numerous empirical parameters and…

Geophysics · Physics 2026-01-09 Shuang Wang , Fei Deng , Peifan Jiang , Zezheng Ni , Bin Wang

The Susceptible-Infected-Susceptible model is a canonical model for emerging disease outbreaks. Such outbreaks are naturally modeled as taking place on networks. A theoretical challenge in network epidemiology is the dynamic correlations…

Physics and Society · Physics 2016-06-29 Chao-Ran Cai , Zhi-Xi Wu , Michael Z. Q. Chen , Petter Holme , Jian-Yue Guan

We develop a physics-informed neural network (PINN) framework for parameter estimation in fractional-order SEIRD epidemic models. By embedding the Caputo fractional derivative into the network residuals via the L1 discretization scheme, our…

Machine Learning · Statistics 2025-09-30 Achraf Zinihi

Among various spatio-temporal prediction tasks, epidemic forecasting plays a critical role in public health management. Recent studies have demonstrated the strong potential of spatio-temporal graph neural networks (STGNNs) in extracting…

Machine Learning · Computer Science 2025-12-30 Yufan Zheng , Wei Jiang , Tong Chen , Alexander Zhou , Nguyen Quoc Viet Hung , Choujun Zhan , Hongzhi Yin

In this paper, we propose a modified susceptible-infected-recovered (SIR) model, in which each node is assigned with an identical capability of active contacts, $A$, at each time step. In contrast to the previous studies, we find that on…

Physics and Society · Physics 2007-05-23 Rui Yang , Bing-Hong Wang , Jie Ren , Wen-Jie Bai , Zhi-Wen Shi , Wen-Xu Wang , Tao Zhou

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

The importance of spatial networks in the spread of an epidemic is an essential aspect in modeling the dynamics of an infectious disease. Additionally, any realistic data-driven model must take into account the large uncertainty in the…

Populations and Evolution · Quantitative Biology 2022-01-17 Giulia Bertaglia , Lorenzo Pareschi

We study the dynamic evolution of COVID-19 cased by the Omicron variant via a fractional susceptible-exposedinfected-removed (SEIR) model. Preliminary data suggest that the symptoms of Omicron infection are not prominent and the…

Numerical Analysis · Mathematics 2022-07-21 Min Cai , George Em Karniadakis , Changpin Li

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

Applications · Statistics 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

Contagious processes, such as spread of infectious diseases, social behaviors, or computer viruses, affect biological, social, and technological systems. Epidemic models for large populations and finite populations on networks have been…

Optimization and Control · Mathematics 2020-04-14 Renato Pagliara , Naomi E. Leonard

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

To simplify mathematical models of disease spread, we often assume equal contact rates among hosts, but real-world scenarios differ. Network-based frameworks help capture these complexities and structural variations in actual systems. We…

Dynamical Systems · Mathematics 2024-07-03 Saswata Das , Mohammad Hossein Samaei , Caterina Scoglio

While most existing epidemic models focus on the influence of isolated factors, infectious disease transmission is inherently shaped by the complex interplay of multiple interacting elements. To better capture real-world dynamics, it is…

Physics and Society · Physics 2025-04-18 Guangyuan Mei , Yao Cai , Su-Su Zhang , Ying Huang , Chuang Liu , Xiu-Xiu Zhan

Data-driven methods have become increasingly more prominent for musculoskeletal modelling due to their conceptually intuitive simple and fast implementation. However, the performance of a pre-trained data-driven model using the data from…

Signal Processing · Electrical Eng. & Systems 2022-11-23 Jie Zhang , Yihui Zhao , Tianzhe Bao , Zhenhong Li , Kun Qian , Alejandro F. Frangi , Sheng Quan Xie , Zhi-Qiang Zhang

The accurate estimation of time-varying transmission rates is fundamental for understanding infectious disease dynamics and implementing effective public health interventions. To this end, we propose an improved inverse method for…

Populations and Evolution · Quantitative Biology 2025-12-17 Shuanglin Jing , Yuting Huang , Hai-Feng Huo

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

Physics and Society · Physics 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta