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Mays celebrated theoretical work of the 70s contradicted the established paradigm by demonstrating that complexity leads to instability in biological systems. Here Mays random-matrix modelling approach is generalized to realistic…

Adaptation and Self-Organizing Systems · Physics 2016-07-11 Lewi Stone

Many growing networks possess accelerating statistics where the number of links added with each new node is an increasing function of network size so the total number of links increases faster than linearly with network size. In particular,…

Molecular Networks · Quantitative Biology 2017-12-22 M. J. Gagen , J. S. Mattick

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

Coherent transport promises to be the basis for an emerging new technology. Notwithstanding, a mechanistic understanding of the fundamental principles behind optimal scattering media is still missing. Here, complex network analysis is…

Quantum Physics · Physics 2013-12-09 Stefano Mostarda , Federico Levi , Diego Prada-Gracia , Florian Mintert , Francesco Rao

Reduction of a two-component FitzHugh-Nagumo model to a single-component model with long-range connection is considered on general networks. The reduced model describes a single chemical species reacting on the nodes and diffusing across…

Pattern Formation and Solitons · Physics 2020-02-19 Timoteo Carletti , Hiroya Nakao

The Turing instability is a paradigmatic route to patterns formation in reaction-diffusion systems. Following a diffusion-driven instability, homogeneous fixed points can become unstable when subject to external perturbation. As a…

Pattern Formation and Solitons · Physics 2015-09-02 Joseph D. Challenger , Raffaella Burioni , Duccio Fanelli

In prokaryotic genomes the number of transcriptional regulators is known to quadratically scale with the total number of protein-coding genes. Toolbox model was recently proposed to explain this scaling for metabolic enzymes and their…

Molecular Networks · Quantitative Biology 2010-09-24 Tin Yau Pang , Sergei Maslov

The persistence of biodiversity of species is a challenging proposition in ecological communities in the face of Darwinian selection. The present article investigates beyond the pairwise competitive interactions and provides a novel…

Populations and Evolution · Quantitative Biology 2022-11-09 Sourin Chatterjee , Sayantan Nag Chowdhury , Dibakar Ghosh , Chittaranjan Hens

Network science provides an indispensable theoretical framework for studying the structure and function of real complex systems. Different network models are often used for finding the rules that govern their evolution, whereby the correct…

Physics and Society · Physics 2020-09-02 Ana Vranić , Marija Mitrović Dankulov

Interconnected ensembles of biological entities are perhaps some of the most complex systems that modern science has encountered so far. In particular, scientists have concentrated on understanding how the complexity of the interacting…

Pattern Formation and Solitons · Physics 2020-11-18 Bram A. Siebert , Cameron L. Hall , James P. Gleeson , Malbor Asllani

Networks exhibiting "accelerating" growth have total link numbers growing faster than linearly with network size and can exhibit transitions from stationary to nonstationary statistics and from random to scale-free to regular statistics at…

Molecular Networks · Quantitative Biology 2017-12-22 M. J. Gagen , J. S. Mattick

The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a minimal model combining tissue mechanics…

Biological Physics · Physics 2022-06-08 P. Recho , A. Hallou , E. Hannezo

Turing patterns on unbounded domains have been widely studied in systems of reaction-diffusion equations. However, up to now, they have not been studied for systems of conservation laws. Here, we (i) derive conditions for Turing instability…

Analysis of PDEs · Mathematics 2018-01-17 Blake Barker , Soyeun Jung , Kevin Zumbrun

We study the dynamics of gene activities in relatively small size biological networks (up to a few tens of nodes), e.g. the activities of cell-cycle proteins during the mitotic cell-cycle progression. Using the framework of deterministic…

Molecular Networks · Quantitative Biology 2009-11-13 Gautier Stoll , Jacques Rougemont , Felix Naef

A social choice procedure is modeled as a repeated Nash game between the social agents, who are communicating with each other through a social communication network modeled by an undirected graph. The agents' criteria for this game are…

Systems and Control · Computer Science 2021-03-02 Athanasios-Rafail Lagos , George P. Papavassilopoulos

Many biological systems approach physical limits to their performance, motivating the idea that their behavior and underlying mechanisms could be determined by such optimality. Nevertheless, optimization as a predictive principle has only…

Biological Physics · Physics 2023-12-05 Thomas R Sokolowski , Thomas Gregor , William Bialek , Gašper Tkačik

The study of pattern-forming instabilities in reaction-diffusion systems on growing or otherwise time-dependent domains arises in a variety of settings, including applications in developmental biology, spatial ecology, and experimental…

Pattern Formation and Solitons · Physics 2022-07-11 Robert A. Van Gorder , Václav Klika , Andrew L. Krause

Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…

Biological Physics · Physics 2016-09-23 Henrik Ronellenfitsch , Eleni Katifori

Reservoir computing is a very promising approach for the prediction of complex nonlinear dynamical systems. Besides capturing the exact short-term trajectories of nonlinear systems, it has also proved to reproduce its characteristic…

Data Analysis, Statistics and Probability · Physics 2020-06-19 Alexander Haluszczynski , Jonas Aumeier , Joschka Herteux , Christoph Räth

This work clarifies the relation between network circuit (topology) and behavior (information transmission and synchronization) in active networks, e.g. neural networks. As an application, we show how to determine a network topology that is…

Chaotic Dynamics · Physics 2015-05-13 M. S. Baptista , J. X. de Carvalho , M. S. Hussein