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We present an analysis of the topologies of a class of networks which are optimal in terms of the requirements of having as short a route as possible between any two nodes while yet keeping the congestion in the network as low as possible.…

Statistical Mechanics · Physics 2009-11-10 Vittoria Colizza , Jayanth R. Banavar , Amos Maritan , Andrea Rinaldo

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

Homeostasis of protein concentrations in cells is crucial for their proper functioning, and this requires concentrations (at their steady-state levels) to be stable to fluctuations. Since gene expression is regulated by proteins such as…

Biological Physics · Physics 2020-11-10 Yipei Guo , Ariel Amir

We estimate density of defects frozen into a biological Turing pattern which was turned on at a finite rate. A self-locking of gene expression in individual cells, which makes the Turing transition discontinuous, stabilizes the pattern…

Biological Physics · Physics 2007-05-23 Jacek Dziarmaga

As two main focuses of the study of complex networks, the community structure and the dynamics on networks have both attracted much attention in various scientific fields. However, it is still an open question how the community structure is…

Physics and Society · Physics 2010-05-11 Xue-Qi Cheng , Hua-Wei Shen

We investigate dynamics near Turing patterns in reaction-diffusion systems posed on the real line. Linear analysis predicts diffusive decay of small perturbations. We construct a "normal form" coordinate system near such Turing patterns…

Analysis of PDEs · Mathematics 2015-10-29 Arnd Scheel , Qiliang Wu

Reaction diffusion systems with Turing instability and mass conservation are studied. In such systems, abrupt decays of stripes follow quasi-stationary states in sequence. At steady state, the distance between stripes is much longer than…

Pattern Formation and Solitons · Physics 2009-11-11 Shuji Ishihara , Mikiya Otsuji , Atsushi Mochizuki

With the development of network science, Turing pattern has been proven to be formed in discrete media such as complex networks, opening up the possibility of exploring it as a generation mechanism in the context of biology, chemistry, and…

Populations and Evolution · Quantitative Biology 2023-10-05 Yong Ye , Jiaying Zhou

Why are large, complex ecosystems stable? Both theory and simulations of current models predict the onset of instability with growing size and complexity, so for decades it has been conjectured that ecosystems must have some unidentified…

Populations and Evolution · Quantitative Biology 2016-08-11 Samuel Johnson , Virginia Domínguez-García , Luca Donetti , Miguel A. Muñoz

Turing patterns are fundamental in biophysics, emerging from short-range activation and long-range inhibition processes. However, their paradigm is based on diffusive transport processes, which yields Turing patters that are less sharp than…

Soft Condensed Matter · Physics 2023-11-13 Benjamin M. Alessio , Ankur Gupta

The problem of Turing instabilities for a reaction-diffusion system defined on a complex Cartesian product networks is considered. To this end we operate in the linear regime and expand the time dependent perturbation on a basis formed by…

Statistical Mechanics · Physics 2014-12-23 Malbor Asllani , Daniel M. Busiello , Timoteo Carletti , Duccio Fanelli , Gwendoline Planchon

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins

In this work we study the effect of density dependent nonlinear diffusion on pattern formation in the Lengyel--Epstein system. Via the linear stability analysis we determine both the Turing and the Hopf instability boundaries and we show…

Pattern Formation and Solitons · Physics 2014-05-20 G. Gambino , M. C. Lombardo , M. Sammartino

(Bi)multi-partite interaction patterns are commonly observed in real world systems which have inhibitory and excitatory couplings. We hypothesize these structural interaction pattern to be stable and naturally arising in the course of…

Physics and Society · Physics 2016-01-20 Sarika Jalan , Sanjiv K. Dwivedi

The emergence of stable disordered patterns in reactive system on spatially homogenous substrate is studied in the context of vegetation patterns in the semi-arid climatic zone. It is shown that reaction-diffusion systems that allow for…

Pattern Formation and Solitons · Physics 2009-11-11 Alon Manor , Nadav M. Shnerb

Long after Turing's seminal Reaction-Diffusion (RD) model, the elegance of his fundamental equations alleviated much of the skepticism surrounding pattern formation. Though Turing model is a simplification and an idealization, it is one of…

Machine Learning · Computer Science 2020-12-09 Litu Rout

A central issue in the study of large complex network systems, such as power grids, financial networks, and ecological systems, is to understand their response to dynamical perturbations. Recent studies recognize that many real networks…

Adaptation and Self-Organizing Systems · Physics 2022-07-26 Chao Duan , Takashi Nishikawa , Deniz Eroglu , Adilson E. Motter

Genetic regulatory networks are defined by their topology and by a multitude of continuously adjustable parameters. Here we present a class of simple models within which the relative importance of topology vs. interaction strengths becomes…

Molecular Networks · Quantitative Biology 2013-08-02 Mikhail Tikhonov , William Bialek

The whole frame of interconnections in complex networks hinges on a specific set of structural nodes, much smaller than the total size, which, if activated, would cause the spread of information to the whole network [1]; or, if immunized,…

Physics and Society · Physics 2015-08-27 Flaviano Morone , Hernan A. Makse

Robustness to perturbation is a key topic in the study of complex systems occurring across a wide variety of applications from epidemiology to biochemistry. Here we analyze the eigenspectrum of the Jacobian matrices associated to a general…

Adaptation and Self-Organizing Systems · Physics 2025-12-11 Shraosi Dawn , Subrata Ghosh , Chandrakala Meena , Tim Rogers , Chittaranjan Hens