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Molecular property prediction and generative design via deep learning models has been the subject of intense research given its potential to accelerate development of new, high-performance materials. More recently, these workflows have been…

Artificial Intelligence · Computer Science 2024-12-16 Nathaniel H. Park , Tiffany J. Callahan , James L. Hedrick , Tim Erdmann , Sara Capponi

Constructing decision trees online is a classical machine learning problem. Existing works often assume that features are readily available for each incoming data point. However, in many real world applications, both feature values and the…

Machine Learning · Computer Science 2025-06-18 Arman Rahbar , Ziyu Ye , Yuxin Chen , Morteza Haghir Chehreghani

The lack of domain-specific data in the pre-training of Large Language Models (LLMs) severely limits LLM-based decision systems in specialized applications, while post-training a model in the scenarios requires significant computational…

Artificial Intelligence · Computer Science 2025-05-05 Zongyuan Li , Pengfei Li , Runnan Qi , Yanan Ni , Lumin Jiang , Hui Wu , Xuebo Zhang , Kuihua Huang , Xian Guo

Recent research has employed reinforcement learning (RL) algorithms to optimize long-term user engagement in recommender systems, thereby avoiding common pitfalls such as user boredom and filter bubbles. They capture the sequential and…

Information Retrieval · Computer Science 2023-01-25 Romain Deffayet , Thibaut Thonet , Jean-Michel Renders , Maarten de Rijke

Although Federated Learning (FL) is promising in knowledge sharing for heterogeneous Artificial Intelligence of Thing (AIoT) devices, their training performance and energy efficacy are severely restricted in practical battery-driven…

Machine Learning · Computer Science 2024-07-10 Jun Xia , Yi Zhang , Yiyu Shi

To design a drug given a biological molecule by using deep learning methods, there are many successful models published recently. People commonly used generative models to design new molecules given certain protein. LiGAN was regarded as…

Machine Learning · Computer Science 2022-11-15 Haotian Zhang , Linxiaoyi Wan

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by grounding responses in external knowledge during inference. However, conventiona RAG systems under-perform on structured tabular data, largely due to coarse…

Computation and Language · Computer Science 2026-05-05 Zebin Guo , Weidong Geng , Ruichen Mao

A major problem with Active Learning (AL) is high training costs since models are typically retrained from scratch after every query round. We start by demonstrating that standard AL on neural networks with warm starting fails, both to…

Machine Learning · Computer Science 2023-12-14 Arnav Das , Gantavya Bhatt , Megh Bhalerao , Vianne Gao , Rui Yang , Jeff Bilmes

Active learning aims to efficiently build a labeled training set by strategically selecting samples to query labels from annotators. In this sequential process, each sample acquisition influences subsequent selections, causing dependencies…

Machine Learning · Computer Science 2025-10-07 Beyza Kalkanli , Tales Imbiriba , Stratis Ioannidis , Deniz Erdogmus , Jennifer Dy

Active learning (AL) is a widely-used training strategy for maximizing predictive performance subject to a fixed annotation budget. In AL one iteratively selects training examples for annotation, often those for which the current model is…

Machine Learning · Computer Science 2019-11-05 David Lowell , Zachary C. Lipton , Byron C. Wallace

Federated learning facilitates the collaborative learning of a global model across multiple distributed medical institutions without centralizing data. Nevertheless, the expensive cost of annotation on local clients remains an obstacle to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Jiayi Chen , Benteng Ma , Hengfei Cui , Yong Xia

One of the biggest challenges that complicates applied supervised machine learning is the need for huge amounts of labeled data. Active Learning (AL) is a well-known standard method for efficiently obtaining labeled data by first labeling…

Machine Learning · Computer Science 2021-08-18 Julius Gonsior , Maik Thiele , Wolfgang Lehner

Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

Designing an inexpensive approximate surrogate model that captures the salient features of an expensive high-fidelity behavior is a prevalent approach in design optimization. In recent times, Deep Learning (DL) models are being used as a…

Machine Learning · Computer Science 2022-07-12 Harsh Vardhan , Janos Sztipanovits

Multi-agent reinforcement learning (MARL) holds substantial promise for intelligent decision-making in complex environments. However, it suffers from a coordination and scalability bottleneck as the number of agents increases. To address…

Multiagent Systems · Computer Science 2025-09-19 Tianyang Duan , Zongyuan Zhang , Songxiao Guo , Dong Huang , Yuanye Zhao , Zheng Lin , Zihan Fang , Dianxin Luan , Heming Cui , Yong Cui

In modern biomedical and econometric studies, longitudinal processes are often characterized by complex time-varying associations and abrupt regime shifts that are shared across correlated outcomes. Standard functional data analysis (FDA)…

Methodology · Statistics 2026-01-28 Baolin Chen , Mengfei Ran

In the paper, we propose an effective and efficient Compositional Federated Learning (ComFedL) algorithm for solving a new compositional Federated Learning (FL) framework, which frequently appears in many data mining and machine learning…

Machine Learning · Computer Science 2023-07-28 Feihu Huang , Junyi Li

Active learning (AL) concerns itself with learning a model from as few labelled data as possible through actively and iteratively querying an oracle with selected unlabelled samples. In this paper, we focus on analyzing a popular type of AL…

Machine Learning · Computer Science 2019-12-03 Minjie Xu , Gary Kazantsev

Molecular discovery is increasingly framed as an inverse design problem: identifying molecular structures that satisfy desired property profiles under feasibility constraints. While recent generative models provide continuous latent…

Machine Learning · Computer Science 2026-03-31 Alexander Arjun Lobo , Urvi Awasthi , Leonid Zhukov

While multifidelity modeling provides a cost-effective way to conduct uncertainty quantification with computationally expensive models, much greater efficiency can be achieved by adaptively deciding the number of required high-fidelity (HF)…

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