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Computing the exact optimal experimental design has been a longstanding challenge in various scientific fields. This problem, when formulated using a specific information function, becomes a mixed-integer nonlinear programming (MINLP)…

Methodology · Statistics 2024-09-30 Ling Liang , Haizhao Yang

Discrete black-box optimization problems are challenging for model-based optimization (MBO) algorithms, such as Bayesian optimization, due to the size of the search space and the need to satisfy combinatorial constraints. In particular,…

Optimization and Control · Mathematics 2022-06-15 Theodore Papalexopoulos , Christian Tjandraatmadja , Ross Anderson , Juan Pablo Vielma , David Belanger

Mixed integer bilinear programs (MIBLPs) offer tools to resolve robotics motion planning problems with orthogonal rotation matrices or static moment balance, but require long solving times. Recent work utilizing data-driven methods has…

Robotics · Computer Science 2024-08-02 Xuan Lin , Gabriel Ikaika Fernandez , Dennis Hong

Mixed Integer Programming (MIP) has been extensively applied in areas requiring mathematical solvers to address complex instances within tight time constraints. However, as the problem scale increases, the complexity of model formulation…

Computation and Language · Computer Science 2024-09-19 Teng Wang , Wing-Yin Yu , Ruifeng She , Wenhan Yang , Taijie Chen , Jianping Zhang

Mixed Integer Linear Programming (MILP) is essential for modeling complex decision-making problems but faces challenges in computational tractability and requires expert formulation. Current deep learning approaches for MILP focus on…

Machine Learning · Computer Science 2025-02-24 Sirui Li , Janardhan Kulkarni , Ishai Menache , Cathy Wu , Beibin Li

Recent research explores optimization using large language models (LLMs) by either iteratively seeking next-step solutions from LLMs or directly prompting LLMs for an optimizer. However, these approaches exhibit inherent limitations,…

Optimization and Control · Mathematics 2024-03-06 Zeyuan Ma , Hongshu Guo , Jiacheng Chen , Guojun Peng , Zhiguang Cao , Yining Ma , Yue-Jiao Gong

This paper proposes a joint decomposition method that combines La- grangian decomposition and generalized Benders decomposition, to efficiently solve multiscenario nonconvex mixed-integer nonlinear programming (MINLP) problems to global…

Optimization and Control · Mathematics 2018-02-22 Emmanuel Ogbe , Xiang Li

The most important ingredient for solving mixed-integer nonlinear programs (MINLPs) to global epsilon-optimality with spatial branch and bound is a tight, computationally tractable relaxation. Due to both theoretical and practical…

Optimization and Control · Mathematics 2019-12-03 Benjamin Müller , Gonzalo Muñoz , Maxime Gasse , Ambros Gleixner , Andrea Lodi , Felipe Serrano

Mixed Integer Linear Programs (MILPs) are highly flexible and powerful tools for modeling and solving complex real-world combinatorial optimization problems. Recently, machine learning (ML)-guided approaches have demonstrated significant…

Artificial Intelligence · Computer Science 2025-06-13 Junyang Cai , Taoan Huang , Bistra Dilkina

A numerical method is developed to solve linear semi-infinite programming problem (LSIP) in which the iterates produced by the algorithm are feasible for the original problem. This is achieved by constructing a sequence of standard linear…

Optimization and Control · Mathematics 2021-01-26 Shuxiong Wang

Mixed integer convex and nonlinear programs, MICP and MINLP, are expressive but require long solving times. Recent work that combines learning methods on solver heuristics has shown potential to overcome this issue allowing for applications…

Robotics · Computer Science 2021-10-05 Xuan Lin , Gabriel I. Fernandez , Dennis W. Hong

Learning-to-optimize (L2O) is an emerging research area in large-scale optimization with applications in data science. Recently, researchers have proposed a novel L2O framework called learned mirror descent (LMD), based on the classical…

Optimization and Control · Mathematics 2024-05-13 Hong Ye Tan , Subhadip Mukherjee , Junqi Tang , Carola-Bibiane Schönlieb

Combinatorial optimization (CO) problems, central to decision-making scenarios like logistics and manufacturing, are traditionally solved using problem-specific algorithms requiring significant domain expertise. While large language models…

Artificial Intelligence · Computer Science 2025-09-24 Xia Jiang , Yaoxin Wu , Minshuo Li , Zhiguang Cao , Yingqian Zhang

Neural networks are known to be vulnerable to adversarial attacks, which are small, imperceptible perturbations that can significantly alter the network's output. Conversely, there may exist large, meaningful perturbations that do not…

Machine Learning · Computer Science 2023-05-18 Tianqi Cui , Thomas Bertalan , George J. Pappas , Manfred Morari , Ioannis G. Kevrekidis , Mahyar Fazlyab

MINLO (mixed-integer nonlinear optimization) formulations of the disjunction between the origin and a polytope via a binary indicator variable is broadly used in nonlinear combinatorial optimization for modeling a fixed cost associated with…

Optimization and Control · Mathematics 2024-04-11 Luze Xu , Jon Lee

The linear programming (LP) approach is, together with value iteration and policy iteration, one of the three fundamental methods to solve optimal control problems in a dynamic programming setting. Despite its simple formulation,…

Systems and Control · Electrical Eng. & Systems 2023-10-31 Lucia Falconi , Andrea Martinelli , John Lygeros

Many modern deep learning applications require balancing multiple objectives that are often conflicting. Examples include multi-task learning, fairness-aware learning, and the alignment of Large Language Models (LLMs). This leads to…

Machine Learning · Computer Science 2025-08-07 Weiyu Chen , Baijiong Lin , Xiaoyuan Zhang , Xi Lin , Han Zhao , Qingfu Zhang , James T. Kwok

While Mixed-integer linear programming (MILP) is NP-hard in general, practical MILP has received roughly 100--fold speedup in the past twenty years. Still, many classes of MILPs quickly become unsolvable as their sizes increase, motivating…

Machine Learning · Computer Science 2023-05-29 Ziang Chen , Jialin Liu , Xinshang Wang , Jianfeng Lu , Wotao Yin

This paper introduces a novel algorithm for Mixed-Integer Nonlinear Programming (MINLP) problems with multilinear interpolations of look-up tables. These problems arise when objective or constraints contain black-box functions only known at…

Large language models (LLMs) are increasingly explored for NP-hard combinatorial optimization problems, but most existing methods emphasize feasible-instance solution generation and do not explicitly address infeasibility detection. We…

Artificial Intelligence · Computer Science 2026-04-15 Yakun Wang , Min Chen , Zeguan Wu , Junyu Liu , Sitao Zhang , Zhenwen Shao
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