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A ternary reaction-diffusion model for early HIV infection dynamics, incorporating logistic growth of target cells, is introduced. According to in vitro and in vivo studies, random movement of target cells, infected cells, and virions and a…

Populations and Evolution · Quantitative Biology 2024-10-21 Florinda Capone , Roberta De Luca , Vincenzo Luongo

In this paper, a class of reaction-diffusion equations for Multiple Sclerosis is presented. These models are derived by means of a diffusive limit starting from a proper kinetic description, taking account of the underlying microscopic…

Quantitative Methods · Quantitative Biology 2026-01-07 Marzia Bisi , Maria Groppi , Giorgio Martalò , Romina Travaglini

This paper introduces a reaction-diffusion-chemotaxis model for bacterial aggregation patterns on the surface of thin agar plates. It is based on the non-linear degenerate cross diffusion model proposed by Kawasaki et al. (J. of Theor.…

Cell Behavior · Quantitative Biology 2013-01-23 J. Francisco Leyva , Carlos Malaga , Ramon G. Plaza

In this paper we study a nonlinear reaction-diffusion system which models an infectious disease caused by bacteria such as those for cholera. One of the significant features in this model is that a certain portion of the recovered human…

Analysis of PDEs · Mathematics 2022-02-01 Hong-Ming Yin , Jun Zou

We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines,…

Tissues and Organs · Quantitative Biology 2026-01-07 Romina Travaglini

We investigated existence of global weak solutions for a system of chemotaxis type with nonlinear degenerate diffusion, arising in modelling Multiple Sclerosis disease. The model consists of three equations describing the evolution of…

Analysis of PDEs · Mathematics 2024-05-10 S. Fagioli , E. Radici , L. Romagnoli

We consider a system of reaction-diffusion equations including chemotaxis terms and coming out of the modeling of multiple sclerosis. The global existence of strong solutions to this system in any dimension is proved, and it is also shown…

Analysis of PDEs · Mathematics 2020-09-29 Laurent Desvillettes , Valeria Giunta , Jeff Morgan , Bao Quoc Tang

Tuberculosis (TB) is an airborne disease caused by the bacterium Mycobacterium tuberculosis (M. tb). Prior to the COVID-19 pandemic, TB was the leading cause of death from an infectious agent globally. However, most people exposed to M. tb…

Quantitative Methods · Quantitative Biology 2026-03-02 James W. G. Doran , Christopher F. Rowlatt , Gibin G. Powathil , Ruth Bowness , Christian A. Yates

We propose two nonlinear random walk models which are suitable for the analysis of both chemotaxis and anomalous transport. We derive the balance equations for the population density for the case when the transition rate for a random walk…

Statistical Mechanics · Physics 2010-10-22 Sergei Fedotov

General conditions are established under which reaction-cross-diffusion systems can undergo spatiotemporal pattern-forming instabilities. Recent work has focused on designing systems theoretically and experimentally to exhibit patterns with…

Pattern Formation and Solitons · Physics 2025-08-26 Edgardo Villar-Sepúlveda , Alan R. Champneys , Andrew L. Krause

We investigate Turing instability and pattern formation in two-dimensional domains for two reaction-diffusion models, obtained as diffusive limits of kinetic equations for mixtures of monatomic and polyatomic gases. The first model is of…

Mathematical Physics · Physics 2026-02-23 Stefano Boccelli , Giorgio Martalò , Romina Travaglini

We set up a rigorous thermodynamic description of reaction-diffusion systems driven out of equilibrium by time-dependent space-distributed chemostats. Building on the assumption of local equilibrium, nonequilibrium thermodynamic potentials…

Statistical Mechanics · Physics 2018-09-12 Gianmaria Falasco , Riccardo Rao , Massimiliano Esposito

In this manuscript we apply stochastic modeling to investigate the risk of reactivation of latent mycobacterial infections in patients undergoing treatment with tumor necrosis factor inhibitors. First, we review the perspective proposed by…

Medical Physics · Physics 2013-04-22 Elena Agliari , Lorenzo Asti , Adriano Barra , Rossana Scrivo , Guido Valesini , Robert S. Wallis

In this paper, we model a nonlinear dynamics of infectious diseases transfer. Particularly, we study possible applications to tubercular infection in models with different profiles (peak values) of the population density dependence on…

Cooperative behaviors arising from bacterial cell-to-cell communication can be modeled by reaction-diffusion equations having only a single diffusible component. This paper presents the following three contributions for the systematic…

Systems and Control · Computer Science 2016-11-15 Hiroki Miyazako , Yutaka Hori , Shinji Hara

The aim of this paper is to contribute to the understanding of the pattern formation phenomenon in reaction-diffusion equations coupled with ordinary differential equations. Such systems of equations arise, for example, from modeling of…

Analysis of PDEs · Mathematics 2016-07-15 Anna Marciniak-Czochra , Grzegorz Karch , Kanako Suzuki

Pattern formation in reaction-diffusion systems is of great importance in surface micro-patterning [Grzybowski et al. Soft Matter. 1, 114 (2005)], self-organization of cellular micro-organisms [Schulz et al. Annu. Rev. Microbiol. 55, 105…

Soft Condensed Matter · Physics 2015-05-19 S. G. Ayodele , F. Varnik , D. Raabe

In this paper we study a mathematical model for an infectious disease such as Cholera without life-time immunity. Due to the different mobility for susceptible, infected human and recovered human hosts, the diffusion coefficients are…

Analysis of PDEs · Mathematics 2020-11-18 Hong-Ming Yin

GTPase molecules are important regulators in cells that continuously run through an activation/deactivation and membrane-attachment/membrane-detachment cycle. Activated GTPase is able to localize in parts of the membranes and to induce cell…

Analysis of PDEs · Mathematics 2011-12-08 Andreas Rätz , Matthias Röger

Along the pathogenesis of Mycobacterium Tuberculosis (MTB), hypoxia-induced dormancy is a process involving the oxygen-depleted environment encountered inside the lung granuloma, where bacilli enter a viable, non-replicating state termed as…

Genomics · Quantitative Biology 2023-11-07 Rohak Jain
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