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4D Computed Tomography (4DCT) is widely used for many clinical applications such as radiotherapy treatment planning, PET and ventilation imaging. However, common 4DCT methods reconstruct multiple breath cycles into a single, arbitrary…
Deciding on appropriate mechanical ventilator management strategies significantly impacts the health outcomes for patients with respiratory diseases. Acute Respiratory Distress Syndrome (ARDS) is one such disease that requires careful…
Clinical decision-making relies heavily on causal reasoning and longitudinal analysis. For example, for a patient with Alzheimer's disease (AD), how will the brain grey matter atrophy in a year if intervened on the A-beta level in…
Remote sensing image fusion aims to create a high-resolution multi/hyper-spectral image from a high-resolution image with limited spectral information and a low-resolution image with abundant spectral data. Recently, deep learning (DL)…
Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…
Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…
Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…
Chest X-rays or chest radiography (CXR), commonly used for medical diagnostics, typically enables limited imaging compared to computed tomography (CT) scans, which offer more detailed and accurate three-dimensional data, particularly…
Diffusion models learn strong image priors that can be leveraged to solve inverse problems like medical image reconstruction. However, for real-world applications such as 3D Computed Tomography (CT) imaging, directly training diffusion…
Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…
Background: Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and dangerous pulmonary diseases in the world. It is forecasted that COPD will be the third deadly disease in the future. Therefore, developing…
This paper proposes a novel, unsupervised super-resolution (SR) approach for performing the SR of a clinical CT into the resolution level of a micro CT ($\mu$CT). The precise non-invasive diagnosis of lung cancer typically utilizes clinical…
Developing a generalist radiology diagnosis system can greatly enhance clinical diagnostics. In this paper, we introduce RadDiag, a foundational model supporting 2D and 3D inputs across various modalities and anatomies, using a…
High-resolution non-invasive 3D study of intact spine and spinal cord morphology on the level of complex vascular and neuronal organization is a crucial issue for the development of treatments for the injuries and pathologies of central…
Computed tomography (CT) has been a powerful diagnostic tool since its emergence in the 1970s. Using CT data, three-dimensional (3D) structures of human internal organs and tissues, such as blood vessels, can be reconstructed using…
Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…
Interstitial lung disease (ILD) is a leading cause of morbidity and mortality in systemic sclerosis (SSc). Chest computed tomography (CT) is the primary imaging modality for diagnosing and monitoring lung complications in SSc patients.…
Artificial intelligence-based analysis of lung ultrasound imaging has been demonstrated as an effective technique for rapid diagnostic decision support throughout the COVID-19 pandemic. However, such techniques can require days- or…
The latest advances in computer-assisted precision medicine are making it feasible to move from population-wide models that are useful to discover aggregate patterns that hold for group-based analysis to patient-specific models that can…
Background: Chronic rhinosinusitis (CRS) is a prevalent and disruptive disease. Medical management including nasal steroid sprays is the primary treatment modality. Computational fluid dynamics (CFD) has been used to characterize sinonasal…