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We investigate the potential of numerical algorithms to decipher the kinetic parameters involved in multi-step chemical reactions. To this end we study a dimerization kinetics of protein as a model system. We follow the dimerization…

Biological Physics · Physics 2014-12-24 Srijeeta Talukder , Shrabani Sen , Ralf Metzler , Suman K Banik , Pinaki Chaudhury

Nonconvex optimization is central to modern machine learning, but the general framework of nonconvex optimization yields weak convergence guarantees that are too pessimistic compared to practice. On the other hand, while convexity enables…

Machine Learning · Computer Science 2025-02-19 Artem Riabinin , Ahmed Khaled , Peter Richtárik

Genetic algorithms, computer programs that simulate natural evolution, are increasingly applied across many disciplines. They have been used to solve various optimisation problems from neural network architecture search to strategic games,…

Neural and Evolutionary Computing · Computer Science 2021-09-14 Aymeric Vie , Alissa M. Kleinnijenhuis , Doyne J. Farmer

Optimization plays a significant role in many areas of science and technology. Most of the industrial optimization problems have inordinately complex structures that render finding their global minima a daunting task. Therefore, designing…

Disordered Systems and Neural Networks · Physics 2021-09-09 Amin Barzegar , Anuj Kankani , Salvatore Mandrà , Helmut G. Katzgraber

This study evaluates the performance of a quantum-classical metaheuristic and a traditional classical mathematical programming solver, applied to two mathematical optimization models for an industry-relevant scheduling problem with…

Quantum Physics · Physics 2025-07-30 Florian Krellner , Abhishek Awasthi , Nico Kraus , Sarah Braun , Michael Poppel , Daniel Porawski

Solving large-scale nonlinear minimization problems is computationally demanding. Nonlinear multilevel minimization (NMM) methods explore the structure of the underlying minimization problem to solve such problems in a computationally…

Numerical Analysis · Mathematics 2022-11-29 Alena Kopaničáková

Genetic algorithms are a powerful tool in optimization for single and multi-modal functions. This paper provides an overview of their fundamentals with some analytical examples. In addition, we explore how they can be used as a parameter…

We consider joint optimization and learning problems arising in real-time decision systems. While most existing work focuses primarily on convex, revenue-based objectives, we extend this line of research to multi-objective formulations. In…

Optimization and Control · Mathematics 2026-04-14 Zijun Li , Aswin Kannan

This paper describes a new approach to solving some stochastic optimization problems for linear dynamic system with various parametric uncertainties. Proposed approach is based on application of tensor formalism for creation the…

Artificial Intelligence · Computer Science 2009-09-15 Vadim Yatsenko

Sustainable development has emerged as a global priority, and industries are increasingly striving to align their operations with sustainable practices. Parallel machine scheduling (PMS) is a critical aspect of production planning that…

Neural and Evolutionary Computing · Computer Science 2023-11-23 Absalom E. Ezugwu

This paper presents several strategies to tune the parameters of metaheuristic methods for (discrete) design optimization of reinforced concrete (RC) structures. A novel utility metric is proposed, based on the area under the average…

Neural and Evolutionary Computing · Computer Science 2021-10-13 Iván Negrin , Dirk Roose , Ernesto Chagoyén

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

Cutting plane methods, particularly outer approximation, are a well-established approach for solving nonlinear discrete optimization problems without relaxing the integrality of decision variables. While powerful in theory, their…

Optimization and Control · Mathematics 2025-11-04 Hòa T. Bùi , Alberto De Marchi

We initiate a systematic study of utilizing predictions to improve over approximation guarantees of classic algorithms, without increasing the running time. We propose a systematic method for a wide class of optimization problems that ask…

Data Structures and Algorithms · Computer Science 2024-11-26 Antonios Antoniadis , Marek Eliáš , Adam Polak , Moritz Venzin

This paper concerns models and convergence principles for dealing with stochasticity in a wide range of algorithms arising in nonlinear analysis and optimization in Hilbert spaces. It proposes a flexible geometric framework within which…

Optimization and Control · Mathematics 2026-02-17 Patrick L. Combettes , Javier I. Madariaga

If a stochastic system during some periods of its evolution can be divided into non-interacting parts, the kinetics of each part can be simulated independently. We show that this can be used in the development of efficient Monte Carlo…

Materials Science · Physics 2009-11-13 V. I. Tokar , H. Dreyssé

Kinematic variables have been playing an important role in collider phenomenology, as they expedite discoveries of new particles by separating signal events from unwanted background events and allow for measurements of particle properties…

High Energy Physics - Phenomenology · Physics 2022-06-28 Roberto Franceschini , Doojin Kim , Kyoungchul Kong , Konstantin T. Matchev , Myeonghun Park , Prasanth Shyamsundar

A systematic mathematical framework for the study of numerical algorithms would allow comparisons, facilitate conjugacy arguments, as well as enable the discovery of improved, accelerated, data-driven algorithms. Over the course of the last…

Numerical Analysis · Mathematics 2020-05-20 Felix Dietrich , Thomas N. Thiem , Ioannis G. Kevrekidis

Optimization problems in engineering and applied mathematics are typically solved in an iterative fashion, by systematically adjusting the variables of interest until an adequate solution is found. The iterative algorithms that govern these…

Optimization and Control · Mathematics 2022-05-31 Laurent Lessard

Optimization algorithms can be interpreted through the lens of dynamical systems as the interconnection of linear systems and a set of subgradient nonlinearities. This dynamical systems formulation allows for the analysis and synthesis of…

Optimization and Control · Mathematics 2026-03-27 Jared Miller , Carsten Scherer , Fabian Jakob , Andrea Iannelli
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