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Deep learning has shown impressive results in reducing noise and artifacts in X-ray computed tomography (CT) reconstruction. Self-supervised CT reconstruction methods are especially appealing for real-world applications because they require…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Dirk Elias Schut , Adriaan Graas , Robert van Liere , Tristan van Leeuwen

In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…

Medical Physics · Physics 2023-01-23 G. Muti , S. Riga , L. Berta , D. Curto , C. De Mattia , M. Felisi , F. Rizzetto , A. Torresin , A. Vanzulli , P. E. Colombo

Computed Tomography is a powerful imaging technique that allows non-destructive visualization of the interior of physical objects in different scientific areas. In traditional reconstruction techniques the object of interest is mostly…

Image and Video Processing · Electrical Eng. & Systems 2019-05-03 Koen Ruymbeek , Wim Vanroose

In this work, we perform direct material reconstruction from spectral CT data using a model based iterative reconstruction (MBIR) approach. Material concentrations are measured in volume fractions, whose total is constrained by a maximum of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-29 Obaidullah Rahman , Ken Sauer , Connor Evans , Ryan Roeder

Algebraic models for the reconstruction problem in X-ray computed tomography (CT) provide a flexible framework that applies to many measurement geometries. For large-scale problems we need to use iterative solvers, and we need stopping…

Numerical Analysis · Mathematics 2021-06-21 Per Christian Hansen , Jakob Sauer Jørgensen , Peter Winkel Rasmussen

Computed Tomography (CT) has been widely adopted in medicine and it is increasingly being used in scientific and industrial applications. Parallelly, research in different mathematical areas concerning discrete inverse problems has led to…

While model-based reconstruction methods have been successfully applied to flat-panel cone-beam CT (FP-CBCT) systems, typical implementations ignore both spatial correlations in the projection data as well as system blurs due to the…

Medical Physics · Physics 2017-06-20 Steven Tilley , Jeffrey H. Siewerdsen , J. Webster Stayman

X-ray computed tomographic infrastructures are medical imaging modalities that rely on the acquisition of rays crossing examined objects while measuring their intensity decrease. Physical measurements are post-processed by mathematical…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Attila Juhos

In this paper, we address the inverse problem of fast, stable, and high-quality wavefront reconstruction from pyramid wavefront sensor data for Adaptive Optics systems on Extremely Large Telescopes. For solving the indicated problem we…

Instrumentation and Methods for Astrophysics · Physics 2019-05-01 Victoria Hutterer , Ronny Ramlau , Iuliia Shatokhina

Flat-panel cone-beam CT (CBCT) has been applied clinically in a number of high-resolution applications. Increasing geometric magnification can potentially improve resolution, but also increases blur due to an extended x-ray focal-spot. We…

Medical Physics · Physics 2016-10-18 Steven Tilley , Wojciech Zbijewski , Jeffrey H. Siewerdsen , J. Webster Stayman

Most existing learning-based methods for solving imaging inverse problems can be roughly divided into two classes: iterative algorithms, such as plug-and-play and diffusion methods leveraging pretrained denoisers, and unrolled architectures…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Matthieu Terris , Samuel Hurault , Maxime Song , Julian Tachella

Classical methods for X-ray computed tomography are based on the assumption that the X-ray source intensity is known, but in practice, the intensity is measured and hence uncertain. Under normal operating conditions, when the exposure time…

Numerical Analysis · Mathematics 2017-07-17 Hari Om Aggrawal , Martin Skovgaard Andersen , Sean Rose , Emil Y. Sidky

This work is concerned with applying iterative image reconstruction, based on constrained total-variation minimization, to low-intensity X-ray CT systems that have a high sampling rate. Such systems pose a challenge for iterative image…

Medical Physics · Physics 2016-11-17 Emil Y. Sidky , Rick Chartrand , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Blind Image Restoration (BIR) methods have achieved remarkable success but falter when faced with Extreme Blind Image Restoration (EBIR), where inputs suffer from severe, compounded degradations beyond their training scope. Directly…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Hongeun Kim , Bryan Sangwoo Kim , Jong Chul Ye

CT imaging works by reconstructing an object of interest from a collection of projections. Traditional methods such as filtered-back projection (FBP) work on projection images acquired around a fixed rotation axis. However, for some CT…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Diyu Yang , Craig A. J. Kemp , Gregery T. Buzzard , Charles A. Bouman

Multi-spectral CT (MSCT) is increasingly used in industrial non-destructive testing and medical diagnosis because of its outstanding performance like material distinguishability. The process of obtaining MSCT data can be modeled as…

Numerical Analysis · Mathematics 2023-06-28 Huiying Pan , Shusen Zhao , Weibin Zhang , Huitao Zhang , Xing Zhao

Recently, an ultra-low-cost linear scan based tomography architecture was proposed by our team. Similar to linear tomosynthesis, the source and detector are translated in opposite directions and the data acquisition system targets on a…

Medical Physics · Physics 2016-10-21 Weiwen Wu , Hengyong Yu , Shaoyu Wang , Fenglin Liu

Unmatched pairs of forward and back projectors are common in X-ray CT computations for large-scale problems; they are caused by the need for fast algorithms that best utilize the computer hardware, and it is an interesting and challenging…

Numerical Analysis · Mathematics 2022-05-30 Per Christian Hansen , Ken Hayami , Keiichi Morikuni

The purpose of the present work is the study of reconstruction properties of a new Molecular Breast Imaging (MBI) device for the early diagnosis of breast cancer, in Limited Angle Tomography (LAT), by using two asymmetric detector heads…

Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Yan Liu , Jonathan Dong , Thanh-An Pham , Francois Marelli , Michael Unser
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