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Autism Spectrum Disorder is a condition characterized by a typical brain development leading to impairments in social skills, communication abilities, repetitive behaviors, and sensory processing. There have been many studies combining…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Junlin Song , Yuzhuo Chen , Yuan Yao , Zetong Chen , Renhao Guo , Lida Yang , Xinyi Sui , Qihang Wang , Xijiao Li , Aihua Cao , Wei Li

This paper presents a simple and effective generalization method for magnetic resonance imaging (MRI) segmentation when data is collected from multiple MRI scanning sites and as a consequence is affected by (site-)domain shifts. We propose…

Image and Video Processing · Electrical Eng. & Systems 2019-10-23 Shahab Aslani , Vittorio Murino , Michael Dayan , Roger Tam , Diego Sona , Ghassan Hamarneh

This report summarizes the outcomes of the ICPR 2024 Competition on Multiple Sclerosis Lesion Segmentation (MSLesSeg). The competition aimed to develop methods capable of automatically segmenting multiple sclerosis lesions in MRI scans.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-11 Alessia Rondinella , Francesco Guarnera , Elena Crispino , Giulia Russo , Clara Di Lorenzo , Davide Maimone , Francesco Pappalardo , Sebastiano Battiato

Simulation-based imaging (SBI) is a blood flow imaging technique that optimally fits a computational fluid dynamics (CFD) simulation to low-resolution, noisy magnetic resonance (MR) flow data to produce a high-resolution velocity field. In…

Numerical Analysis · Mathematics 2021-10-01 Charles J. Naudet , Johannes Toger , Matthew J. Zahr

Multiple sclerosis (MS) is a progressive inflammatory and neurodegenerative disease of the central nervous system affecting over 2.5 million people globally. In-clinic six-minute walk test (6MWT) is a widely used objective measure to…

With an estimated five million new stroke survivors every year and a rapidly aging population suffering from hyperintensities and diseases of presumed vascular origin that affect white matter and contribute to cognitive decline, it is…

Neurons and Cognition · Quantitative Biology 2020-05-21 Abdelrahman Zayed , Yasser Iturria-Medina , Arno Villringer , Bernhard Sehm , Christopher J. Steele

Automated segmentation of multiple sclerosis (MS) lesions from MRI scans is important to quantify disease progression. In recent years, convolutional neural networks (CNNs) have shown top performance for this task when a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jiacheng Wang , Hao Li , Han Liu , Dewei Hu , Daiwei Lu , Keejin Yoon , Kelsey Barter , Francesca Bagnato , Ipek Oguz

Weakly supervised multi-label classification (WSML) task, which is to learn a multi-label classification using partially observed labels per image, is becoming increasingly important due to its huge annotation cost. In this work, we first…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Youngwook Kim , Jae Myung Kim , Zeynep Akata , Jungwoo Lee

Voxel-based lesion-symptom mapping (VLSM) is a major method for studying brain-behavior relationships that leverages modern neuroimaging analysis techniques to build on the classic approach of examining the relationship between location of…

Applications · Statistics 2016-06-03 Daniel Mirman , Jon-Frederick Landrigan , Spiro Kokolis , Sean Verillo , Casey Ferrara

Multiple Sclerosis (MS) is a chronic progressive neurological disease characterized by the development of lesions in the white matter of the brain. T2-fluid-attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2022-09-12 Jueqi Wang , Derek Berger , Erin Mazerolle , Othman Soufan , Jacob Levman

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

We demonstrate a simple and effective automated method for the segmentation of glomeruli from large (~1 gigapixel) histopathological whole-slide images (WSIs) of thin renal tissue sections and biopsies, using an adaptation of the well-known…

Tissues and Organs · Quantitative Biology 2017-09-21 Olivier Simon , Rabi Yacoub , Sanjay Jain , Pinaki Sarder

There are many clinical contexts which require accurate detection and segmentation of all focal pathologies (e.g. lesions, tumours) in patient images. In cases where there are a mix of small and large lesions, standard binary cross entropy…

Image and Video Processing · Electrical Eng. & Systems 2022-05-19 Brennan Nichyporuk , Justin Szeto , Douglas L. Arnold , Tal Arbel

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Churan Wang , Fei Gao , Lijun Yan , Siwen Wang , Yizhou Yu , Yizhou Wang

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

While diffusion MRI has been extremely promising in the study of MTBI, identifying patients with recent MTBI remains a challenge. The literature is mixed with regard to localizing injury in these patients, however, gray matter such as the…

Computer Vision and Pattern Recognition · Computer Science 2017-08-31 Shervin Minaee , Yao Wang , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W. Lui

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori

Radiologists use various imaging modalities to aid in different tasks like diagnosis of disease, lesion visualization, surgical planning and prognostic evaluation. Most of these tasks rely on the the accurate delineation of the anatomical…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Ronnie Rajan , Rachana Sathish , Debdoot Sheet

Lesions that appear hyperintense in both Fluid Attenuated Inversion Recovery (FLAIR) and T2-weighted magnetic resonance images (MRIs) of the human brain are common in the brains of the elderly population and may be caused by ischemia or…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hans E. Atlason , Askell Love , Sigurdur Sigurdsson , Vilmundur Gudnason , Lotta M. Ellingsen