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Midline shift (MLS) is a well-established factor used for outcome prediction in traumatic brain injury, stroke and brain tumors. The importance of automatic estimation of MLS was recently highlighted by ACR Data Science Institute. In this…

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

White Matter Injury (WMI) is the most prevalent brain injury in the preterm neonate leading to developmental deficits. However, detecting WMI in Magnetic Resonance (MR) images of preterm neonate brains using traditional WM…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Subhayan Mukherjee , Irene Cheng , Steven Miller , Jessie Guo , Vann Chau , Anup Basu

Lesion volume is an important predictor for prognosis in breast cancer. We make a step towards a more accurate lesion volume measurement on digital mammograms by developing a model that allows to estimate lesion volumes on processed…

Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system whose molecular mechanisms remain incompletely understood. In this study, we developed an end-to-end machine learning pipeline to analyze transcriptomic…

In recent years, several convolutional neural network (CNN) methods have been proposed for the automated white matter lesion segmentation of multiple sclerosis (MS) patient images, due to their superior performance compared with those of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-01 Sergi Valverde , Mostafa Salem , Mariano Cabezas , Deborah Pareto , Joan C. Vilanova , Lluís Ramió-Torrentà , Àlex Rovira , Joaquim Salvi , Arnau Oliver , Xavier Lladó

We consider machine-learning-based malignancy prediction and lesion identification from clinical dermatological images, which can be indistinctly acquired via smartphone or dermoscopy capture. Additionally, we do not assume that images…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Meng Xia , Meenal K. Kheterpal , Samantha C. Wong , Christine Park , William Ratliff , Lawrence Carin , Ricardo Henao

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

Demyelinating disorders of the central nervous system may have multiple causes, the most common are infections, autoimmune responses, genetic or vascular etiology. Demyelination lesions are characterized by areas were the myelin sheath of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Maria Popa , Gabriela Adriana Visa

Anomaly detection and localization in medical imaging remain critical challenges in healthcare. This paper introduces Spatial-MSMA (Multiscale Score Matching Analysis), a novel unsupervised method for anomaly localization in volumetric…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Ahsan Mahmood , Junier Oliva , Martin Styner

White matter hyperintensities (WMH) are bright regions on T2-weighted magnetic resonance imaging (MRI) scans and are associated with cerebrovascular pathology and neurodegeneration, including myelin loss. While Luxol Fast Blue…

Accurate lesion-level segmentation on MRI is critical for multiple sclerosis (MS) diagnosis, prognosis, and disease monitoring. However, current evaluation practices largely rely on semantic segmentation post-processed with connected…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Maxence Wynen , Pedro M. Gordaliza , Maxime Istasse , Anna Stölting , Pietro Maggi , Benoît Macq , Meritxell Bach Cuadra

Background: Cognitive impairment in multiple sclerosis (MS) is driven by both focal inflammation and compartmentalized neurodegeneration, yet the relative effect of lesion-independent thalamic atrophy on information processing speed (IPS)…

Neurons and Cognition · Quantitative Biology 2026-02-19 Arshya Pooladi-Darvish , Heather Rosehart , Marina R. Everest , Ali R. Khan , Sarah A. Morrow

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Basit Alawode , Arif Mahmood , Muaz Khalifa Al-Radi , Shahad Albastaki , Asim Khan , Muhammad Bilal , Moshira Ali Abdalla , Mohammed Bennamoun , Sajid Javed

The elasticity of soft tissues has been widely considered as a characteristic property to differentiate between healthy and vicious tissues and, therefore, motivated several elasticity imaging modalities, such as Ultrasound Elastography,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-30 Weiguo Cao , Marc J. Pomeroy , Zhengrong Liang , Yongfeng Gao , Yongyi Shi , Jiaxing Tan , Fangfang Han , Jing Wang , Jianhua Ma , Hongbin Lu , Almas F. Abbasi , Perry J. Pickhardt

Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

The evaluation and treatment of acute cerebral ischemia requires a technique that can determine the total area of tissue at risk for infarction using diagnostic magnetic resonance imaging (MRI) sequences. Typical MRI data sets consist of…

Computer Vision and Pattern Recognition · Computer Science 2016-06-14 Vishwa S. Parekh , Jeremy R. Jacobs , Michael A. Jacobs

Personalized longitudinal disease assessment is central to quickly diagnosing, appropriately managing, and optimally adapting the therapeutic strategy of multiple sclerosis (MS). It is also important for identifying the idiosyncratic…

Reconstructing digital brain phantoms in the form of voxel-based, multi-channeled tissue probability maps for individual subjects is essential for capturing brain anatomical variability, understanding neurological diseases, as well as for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Utkarsh Gupta , Emmanouil Nikolakakis , Moritz Zaiss , Razvan Marinescu
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