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Various biological cells secrete diffusing chemical compounds into their environment for communication purposes. Secretion usually takes place over the cell membrane in a spatially heterogeneous manner. Mathematical models of these…

Numerical Analysis · Mathematics 2025-11-20 Qiyao Peng , Sander C. Hille

Biological cells can release compounds into their direct environment, generally inhomogeneously over their cell membrane, after which the compounds spread by diffusion. In mathematical modelling and simulation of a collective of such cells,…

Numerical Analysis · Mathematics 2025-05-13 Qiyao Peng , Sander C. Hille

For the sake of computational efficiency and for theoretical purposes, in mathematical modelling, the Dirac Delta distributions are often utilized as a replacement for cells or vesicles, since the size of cells or vesicles is much smaller…

Numerical Analysis · Mathematics 2023-11-09 Qiyao Peng , Sander C. Hille

We propose an analytical method for solving the problem of barrierless reactions in solution, modeled by a particle undergoing diffusive motion under the influence of both reactant and product potentials. The coupling between these two…

Chemical Physics · Physics 2015-06-16 Aniruddha Chakraborty

Problems involving the capture of a moving entity by a trap occur in a variety of physical situations, the moving entity being an electron, an excitation, an atom, a molecule, a biological object such as a receptor cluster, a cell, or even…

Statistical Mechanics · Physics 2015-06-17 K. Spendier , S. Sugaya , V. M. Kenkre

We propose an analytical method for finding the time domain solution for the problem of electronic relaxation of a molecule in solution. The relaxation process is modeled by the decay of a diffusing probability distribution through an…

Chemical Physics · Physics 2020-04-28 Saravanan Rajendran , Aniruddha Chakraborty

We consider several mathematical issues regarding models that simulate forces exerted by cells. Since the size of cells is much smaller than the size of the domain of computation, one often considers point forces, modelled by Dirac Delta…

Numerical Analysis · Mathematics 2022-04-06 Qiyao Peng , Fred Vermolen

Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…

Biological Physics · Physics 2026-02-13 Louis Brezin , Kyle J. Shaffer , Kirill S. Korolev

In this paper, we consider the one-dimensional semirelativistic Schr\"{o}dinger equation for a particle interacting with $N$ Dirac delta potentials. Using the heat kernel techniques, we establish a resolvent formula in terms of an $N \times…

Mathematical Physics · Physics 2017-02-22 Fatih Erman , Manuel Gadella , Haydar Uncu

This paper proposes a novel reaction-diffusion system approximation tailored for singular diffusion problems, typified by the fast diffusion equation. While such approximation methods have been successfully applied to degenerate parabolic…

Analysis of PDEs · Mathematics 2026-04-01 Hideki Murakawa , Florian Salin

The behaviour is investigated of solutions to a diffusion equation on the real line with nonlocal and singular reaction term, i.e., given by a Dirac source or sink at the origin. It gives a simplified representation of for example a control…

Analysis of PDEs · Mathematics 2026-05-19 Xiao Yang , Qiyao Peng , Sander C. Hille

In this paper, we study the local behaviour of solutions near the fixed points of a reaction-diffusion equation with discontinuous nonlinearity. By employing an appropriate linearization around the fixed points, which involves the Dirac…

Dynamical Systems · Mathematics 2025-07-31 José Valero

We present an efficient point-particle approach to simulate reaction-diffusion processes of spherical absorbing particles in the diffusion-limited regime, as simple models of cellular uptake. The exact solution for a single absorber is used…

Fluid Dynamics · Physics 2018-02-14 A. Sozza , F. Piazza , M. Cencini , F. De Lillo , G. Boffetta

This paper establishes existence, uniqueness, and an L^1-comparison principle for weak solutions of a PDE system modeling phase transition reaction-diffusion in congested crowd motion. We consider a general reaction term and mixed…

Analysis of PDEs · Mathematics 2025-09-17 Noureddine Igbida , Fahd Karami , Driss Meskine

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

Analysis of PDEs · Mathematics 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

In this paper we introduce a model describing diffusion of species by a suitable regularization of a "forward-backward" parabolic equation. In particular, we prove existence and uniqueness of solutions, as well as continuous dependence on…

Analysis of PDEs · Mathematics 2015-08-14 Elena Bonetti , Pierluigi Colli , Giuseppe Tomassetti

The reversible reactions like A+B <-> C in the many-component diffusive system affect the diffusive properties of the constituents. The effective conjugation of irreversible processes of different dimensionality takes place due to the…

Other Condensed Matter · Physics 2007-05-23 Serge Shpyrko , Vladimir M. Sysoev

Chemical reactions inside cells are generally considered to happen within fixed-size compartments. Needless to say, cells and their compartments are highly dynamic. Thus, such stringent assumptions may not reflect biochemical reality, and…

Quantitative Methods · Quantitative Biology 2016-02-17 Atiyo Ghosh , Tatiana T. Marquez-Lago

The study of reaction-diffusion systems on networks is of paramount relevance for the understanding of nonlinear processes in systems where the topology is intrinsically discrete, such as the brain. Until now reaction-diffusion systems have…

Pattern Formation and Solitons · Physics 2025-10-22 Lorenzo Giambagli , Lucille Calmon , Riccardo Muolo , Timoteo Carletti , Ginestra Bianconi

We propose an analytical method for understanding the problem of multi-channel electron transfer reaction in solution, modeled by a particle undergoing diffusive motion under the influence of one donor and several acceptor potentials. The…

Quantum Physics · Physics 2015-06-30 Aniruddha Chakraborty
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