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Quantum computers process information with the laws of quantum mechanics. Current quantum hardware is noisy, can only store information for a short time, and is limited to a few quantum bits, i.e., qubits, typically arranged in a planar…

Grover's algorithm is a cornerstone of quantum search algorithm, offering quadratic speedup for unstructured problems. However, limited qubit counts and noise in today's noisy intermediate-scale quantum (NISQ) devices hinder large-scale…

Quantum Physics · Physics 2026-01-08 Mei Ian Sam , Tzu-Ling Kuo , Tai-Yue Li

We assess the potential of quantum computing to accelerate computation of central tasks in genomics, focusing on often-neglected theoretical limitations. We discuss state-of-the-art challenges of quantum search, optimization, and machine…

Quantum Physics · Physics 2026-01-09 Aurora Maurizio , Guglielmo Mazzola

Unlike most classical algorithms that take an input and give the solution directly as an output, quantum algorithms produce a quantum circuit that works as an indirect solution to computationally hard problems. In the full quantum computing…

Quantum Physics · Physics 2025-05-22 Yikai Mao , Shaswot Shresthamali , Masaaki Kondo

This paper presents the Pauli-based Circuit Optimization, Analysis, and Synthesis Toolchain (PCOAST), a framework for quantum circuit optimizations based on the commutative properties of Pauli strings. Prior work has demonstrated that…

Quantum Physics · Physics 2023-05-25 Jennifer Paykin , Albert T. Schmitz , Mohannad Ibrahim , Xin-Chuan Wu , A. Y. Matsuura

With the increasing capabilities of quantum systems, the efficient, practical execution of quantum programs is becoming more critical. Each execution includes compilation time, which accounts for substantial overhead of the overall program…

Quantum Physics · Physics 2026-01-01 Felix Zilk , Alessandro Tundo , Vincenzo De Maio , Ivona Brandic

Quantum computer simulators are an indispensable tool for prototyping quantum algorithms and verifying the functioning of existing quantum computer hardware. The current largest quantum computers feature more than one thousand qubits,…

Quantum Physics · Physics 2025-01-28 Gabin Schieffer , Stefano Markidis , Ivy Peng

In one-way quantum computation (1WQC) model, universal quantum computations are performed using measurements to designated qubits in a highly entangled state. The choices of bases for these measurements as well as the structure of the…

Emerging Technologies · Computer Science 2016-04-20 Eesa Nikahd , Mahboobeh Houshmand , Morteza Saheb Zamani , Mehdi Sedighi

Quantum circuit simulations are critical for evaluating quantum algorithms and machines. However, the number of state amplitudes required for full simulation increases exponentially with the number of qubits. In this study, we leverage data…

One of the core research questions in the theory of quantum computing is to find out to what precise extent the classical simulation of a noisy quantum circuits is possible and where potential quantum advantages can set in. In this work, we…

Quantum Physics · Physics 2026-01-09 Janek Denzler , Jose Carrasco , Jens Eisert , Tommaso Guaita

Recent developments in quantum hardware indicate that systems featuring more than 50 physical qubits are within reach. At this scale, classical simulation will no longer be feasible and there is a possibility that such quantum devices may…

Quantum Physics · Physics 2018-03-06 Mathias Soeken , Thomas Häner , Martin Roetteler

Quantum algorithms often apply classical operations, such as arithmetic or predicate checks, over a quantum superposition of classical data; these so-called oracles are often the largest components of a quantum program. To ease the…

Quantum Physics · Physics 2022-04-21 Liyi Li , Finn Voichick , Kesha Hietala , Yuxiang Peng , Xiaodi Wu , Michael Hicks

In this work we present two techniques that tremendously increase the performance of tensor-network based quantum circuit simulations. The techniques are implemented in the QTensor package and benchmarked using Quantum Approximate…

Quantum Physics · Physics 2021-07-01 Danylo Lykov , Yuri Alexeev

Recent advances in quantum architectures and computing have motivated the development of new optimizing compilers for quantum programs or circuits. Even though steady progress has been made, existing quantum optimization techniques remain…

Programming Languages · Computer Science 2025-02-28 Jatin Arora , Mingkuan Xu , Sam Westrick , Pengyu Liu , Dantong Li , Yongshan Ding , Umut A. Acar

Recent demonstrations of superconducting quantum computers by Google and IBM and trapped-ion computers from IonQ fueled new research in quantum algorithms, compilation into quantum circuits, and empirical algorithmics. While online access…

Quantum Physics · Physics 2020-11-26 Aneeqa Fatima , Igor L. Markov

We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

Decoherence of quantum hardware is currently limiting its practical applications. At the same time, classical algorithms for simulating quantum circuits have progressed substantially. Here, we demonstrate a hybrid framework that integrates…

A range of quantum algorithms, especially those leveraging variational parameterization and circuit-based optimization, are being studied as alternatives for solving classically intractable combinatorial optimization problems (COPs).…

Quantum Physics · Physics 2025-06-18 Monit Sharma , Hoong Chuin Lau

Quantum circuit simulation is paramount to the verification and optimization of quantum algorithms, and considerable research efforts have been made towards efficient simulators. While circuits often contain high-level gates such as oracles…

Quantum Physics · Physics 2026-05-06 Adam Husted Kjelstrøm , Andreas Pavlogiannis , Jaco van de Pol

Quantum computing holds great potential to accelerate the process of solving complex combinatorial optimization problems. The Distributed Quantum Approximate Optimization Algorithm (DQAOA) addresses high-dimensional, dense problems using…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Zhihao Xu , Srikar Chundury , Seongmin Kim , Amir Shehata , Xinyi Li , Ang Li , Tengfei Luo , Frank Mueller , In-Saeng Suh
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