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As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

Cardiac amyloidosis, a rare and highly morbid condition, presents significant challenges for detection through echocardiography. Recently, there has been a surge in proposing machine-learning algorithms to identify cardiac amyloidosis, with…

Image and Video Processing · Electrical Eng. & Systems 2024-06-10 Zishun Feng , Joseph A. Sivak , Ashok K. Krishnamurthy

Voice disorders negatively impact the quality of daily life in various ways. However, accurately recognizing the category of pathological features from raw audio remains a considerable challenge due to the limited dataset. A promising…

Sound · Computer Science 2024-10-08 Lipeng Shen , Yifan Xiong , Dongyue Guo , Wei Mo , Lingyu Yu , Hui Yang , Yi Lin

This study proposes a novel perspective on multimodal deep learning for biomedical signal classification, systematically analyzing how complementary feature domains impact model performance. While fusing multiple domains often presumes…

Machine Learning · Computer Science 2025-08-05 Timothy Oladunni , Alex Wong

Technological advances in medical data collection, such as high-throughput genomic sequencing and digital high-resolution histopathology, have contributed to the rising requirement for multimodal biomedical modelling, specifically for…

Machine Learning · Computer Science 2024-10-29 Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Suicide is one of the leading causes of death among adolescents. Previous suicide risk prediction studies have primarily focused on either textual or acoustic information in isolation, the integration of multimodal signals, such as speech…

Sound · Computer Science 2025-09-03 Wenqiang Sun , Han Yin , Jisheng Bai , Jianfeng Chen

Multimodal clinical prediction is widely used to integrate heterogeneous data such as Electronic Health Records (EHR) and biosignals. However, existing methods tend to rely on static modality integration schemes and simple fusion…

Machine Learning · Computer Science 2026-01-16 Jongseok Kim , Seongae Kang , Jonghwan Shin , Yuhan Lee , Ohyun Jo

Machine learning holds promise for advancing clinical decision support, yet it remains unclear when multimodal learning truly helps in practice, particularly under modality missingness and fairness constraints. In this work, we conduct a…

Machine Learning · Computer Science 2026-03-02 Kejing Yin , Haizhou Xu , Wenfang Yao , Chen Liu , Zijie Chen , Yui Haang Cheung , William K. Cheung , Jing Qin

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…

Computation and Language · Computer Science 2022-11-09 Loukas Ilias , Dimitris Askounis , John Psarras

Previous research on the diagnosis of Bipolar disorder has mainly focused on resting-state functional magnetic resonance imaging. However, their accuracy can not meet the requirements of clinical diagnosis. Efficient multimodal fusion…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Guoxin Wang , Sheng Shi , Shan An , Fengmei Fan , Wenshu Ge , Qi Wang , Feng Yu , Zhiren Wang

Body-conduction microphone signals (BMS) bypass airborne sound, providing strong noise resistance. However, a complementary modality is required to compensate for the inherent loss of high-frequency information. In this study, we propose a…

Sound · Computer Science 2025-08-29 Yunsik Kim , Yoonyoung Chung

Alzheimer's disease (AD) is a common neurodegenerative disease among the elderly. Early prediction and timely intervention of its prodromal stage, mild cognitive impairment (MCI), can decrease the risk of advancing to AD. Combining…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Xiangyang Hu , Xiangyu Shen , Yifei Sun , Xuhao Shan , Wenwen Min , Liyilei Su , Xiaomao Fan , Ahmed Elazab , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan

This study proposes an innovative multimodal fusion model based on a teacher-student architecture to enhance the accuracy of depression classification. Our designed model addresses the limitations of traditional methods in feature fusion…

Computation and Language · Computer Science 2025-02-03 Lindy Gan , Yifan Huang , Xiaoyang Gao , Jiaming Tan , Fujun Zhao , Tao Yang

Early detection of cognitive disorders such as Alzheimer's disease is critical for enabling timely clinical intervention and improving patient outcomes. In this work, we introduce CogniAlign, a multimodal architecture for Alzheimer's…

Machine Learning · Computer Science 2025-10-27 David Ortiz-Perez , Manuel Benavent-Lledo , Javier Rodriguez-Juan , Jose Garcia-Rodriguez , David Tomás

Artificial intelligence (AI) models trained on audio data may have the potential to rapidly perform clinical tasks, enhancing medical decision-making and potentially improving outcomes through early detection. Existing technologies depend…

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Medical patient data is always multimodal. Images, text, age, gender, histopathological data are only few examples for different modalities in this context. Processing and integrating this multimodal data with deep learning based methods is…

Artificial Intelligence · Computer Science 2025-09-11 Christian Gapp , Elias Tappeiner , Martin Welk , Rainer Schubert

This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…

Signal Processing · Electrical Eng. & Systems 2024-04-22 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Carol Espy-Wilson