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Recently, machine learning-based semantic segmentation algorithms have demonstrated their potential to accurately segment regions and contours in medical images, allowing the precise location of anatomical structures and abnormalities.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Yifei Wang , Chuhong Zhu

In recent years, various large foundation models have been proposed for image segmentation. There models are often trained on large amounts of data corresponding to general computer vision tasks. Hence, these models do not perform well on…

Computer Vision and Pattern Recognition · Computer Science 2024-05-20 Jay N. Paranjape , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

In weakly supervised medical image segmentation, the absence of structural priors and the discreteness of class feature distribution present a challenge, i.e., how to accurately propagate supervision signals from local to global regions…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Yu Lei , Haolun Luo , Lituan Wang , Zhenwei Zhang , Lei Zhang

The prowess that makes few-shot learning desirable in medical image analysis is the efficient use of the support image data, which are labelled to classify or segment new classes, a task that otherwise requires substantially more training…

Although new vision foundation models such as Segment Anything Model 2 (SAM2) have significantly enhanced zero-shot image segmentation capabilities, reliance on human-provided prompts poses significant challenges in adapting SAM2 to medical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Yang Xing , Jiong Wu , Yuheng Bu , Kuang Gong

We propose a test-time adaptation method for cross-domain image segmentation. Our method is simple: Given a new unseen instance at test time, we adapt a pre-trained model by conducting instance-specific BatchNorm (statistics) calibration.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Yuliang Zou , Zizhao Zhang , Chun-Liang Li , Han Zhang , Tomas Pfister , Jia-Bin Huang

The success of deep learning methods in medical image segmentation tasks heavily depends on a large amount of labeled data to supervise the training. On the other hand, the annotation of biomedical images requires domain knowledge and can…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Xinrong Hu , Dewen Zeng , Xiaowei Xu , Yiyu Shi

Current methods for developing foundation models in medical image segmentation rely on two primary assumptions: a fixed set of classes and the immediate availability of a substantial and diverse training dataset. However, this can be…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Xiaoyang Chen , Hao Zheng , Yifang Xie , Yuncong Ma , Tengfei Li

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Despite the recent success of deep learning methods at achieving new state-of-the-art accuracy for medical image segmentation, some major limitations are still restricting their deployment into clinics. One major limitation of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Lucas Fidon

Despite that the segment anything model (SAM) achieved impressive results on general-purpose semantic segmentation with strong generalization ability on daily images, its demonstrated performance on medical image segmentation is less…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Shizhan Gong , Yuan Zhong , Wenao Ma , Jinpeng Li , Zhao Wang , Jingyang Zhang , Pheng-Ann Heng , Qi Dou

Unsupervised domain adaptation is useful in medical image segmentation. Particularly, when ground truths of the target images are not available, domain adaptation can train a target-specific model by utilizing the existing labeled images…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Fuping Wu , Xiahai Zhuang

Accurate and efficient 3D medical image segmentation is essential for clinical AI, where models must remain reliable under stringent memory, latency, and data availability constraints. Transformer-based methods achieve strong accuracy but…

Machine Learning · Computer Science 2026-03-10 Kavyansh Tyagi , Vishwas Rathi , Puneet Goyal

Medical image segmentation is fundamental to clinical decision-making, yet existing models remain fragmented. They are usually trained on single knowledge sources and specific to individual tasks, modalities, or organs. This fragmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Bangwei Guo , Yunhe Gao , Meng Ye , Difei Gu , Yang Zhou , Leon Axel , Dimitris Metaxas

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi

Surgical image segmentation is highly challenging, primarily due to scarcity of annotated data. Generalist prompted segmentation models like the Segment-Anything Model (SAM) can help tackle this task, but because they require image-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Aditya Murali , Farahdiba Zarin , Adrien Meyer , Pietro Mascagni , Didier Mutter , Nicolas Padoy

Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Benjamin Towle , Xin Chen , Ke Zhou

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie