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Acute Leukemia is the most common hematologic malignancy in children and adolescents. A key methodology in the diagnostic evaluation of this malignancy is immunophenotyping based on Multiparameter Flow Cytometry (FCM). However, this…

Machine Learning · Computer Science 2024-06-27 Elpiniki Maria Lygizou , Michael Reiter , Margarita Maurer-Granofszky , Michael Dworzak , Radu Grosu

Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Xiongchao Chen , Bo Zhou , Xueqi Guo , Huidong Xie , Qiong Liu , James S. Duncan , Albert J. Sinusas , Chi Liu

The recent development of high-throughput sequencing creates a large collection of multi-omics data, which enables researchers to better investigate cancer molecular profiles and cancer taxonomy based on molecular subtypes. Integrating…

Genomics · Quantitative Biology 2024-01-25 Bingjun Li , Sheida Nabavi

Accurate identification and localisation of brain tumours from medical images remain challenging due to tumour variability and structural complexity. Convolutional Neural Networks (CNNs), particularly ResNet and Unet, have made significant…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Peixin Dai , Jingsi Zhang , Zhitao Shu

Feature vectors provided by pre-trained deep artificial neural networks have become a dominant source for image representation in recent literature. Their contribution to the performance of image analysis can be improved through finetuning.…

Medical image segmentation plays a vital role in various clinical applications, enabling accurate delineation and analysis of anatomical structures or pathological regions. Traditional CNNs have achieved remarkable success in this field.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Computed tomography (CT) generates a stack of cross-sectional images covering a region of the body. The visual assessment of these images for the identification of potential abnormalities is a challenging and time consuming task due to the…

Machine Learning · Statistics 2016-10-03 Petros-Pavlos Ypsilantis , Giovanni Montana

Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia. By combining morphological and transcriptomic data, we can gain insights into cellular functions and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Gizem Mert , Ario Sadafi , Raheleh Salehi , Nassir Navab , Carsten Marr

Astrocytes are critical glial cells whose altered morphology and density are hallmarks of many neurological disorders. However, their intricate branching and stain dependent variability make automated detection of histological images a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Xizhe Zhang , Jiayang Zhu

Fault detection and diagnosis is significant for reducing maintenance costs and improving health and safety in chemical processes. Convolution neural network (CNN) is a popular deep learning algorithm with many successful applications in…

Machine Learning · Computer Science 2023-07-11 Mengxuan Li , Peng Peng , Min Wang , Hongwei Wang

PURPOSE: Deep learning methods for classifying prostate cancer (PCa) in ultrasound images typically employ convolutional networks (CNNs) to detect cancer in small regions of interest (ROI) along a needle trace region. However, this approach…

Complex biological networks are fundamental to biomedical science, capturing interactions among molecules, cells, genes, and tissues. Deciphering these networks is critical for understanding health and disease, yet their scale and…

Machine Learning · Computer Science 2025-12-09 Sakib Mostafa , Lei Xing , Md. Tauhidul Islam

This research proposes a very lightweight model "Fibonacci-Net" along with a novel pooling technique, for automatic brain tumor classification from imbalanced Magnetic Resonance Imaging (MRI) datasets. Automatic brain tumor detection from…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Santanu Roy , Ashvath Suresh , Archit Gupta , Shubhi Tiwari , Palak Sahu , Prashant Adhikari , Yuvraj S. Shekhawat

Thousands of individuals succumb annually to leukemia alone. As artificial intelligence-driven technologies continue to evolve and advance, the question of their applicability and reliability remains unresolved. This study aims to utilize…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Alaa Awad , Salah A. Aly

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

State-of-the-art (SOTA) Convolutional Neural Networks (CNNs) are criticized for their extensive computational power, long training times, and large datasets. To overcome this limitation, we propose a reasonable network (R-Net), a…

Tissues and Organs · Quantitative Biology 2025-09-23 Rokonozzaman Ayon , Md Taimur Ahad , Bo Song , Yan Li

Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Wei Lou , Guanbin Li , Xiang Wan , Haofeng Li

Developing computational tools for integrative analysis across multiple types of omics data has been of immense importance in cancer molecular biology and precision medicine research. While recent advancements have yielded integrative…

In the medical field, accurate diagnosis of lung cancer is crucial for treatment. Traditional manual analysis methods have significant limitations in terms of accuracy and efficiency. To address this issue, this paper proposes a deep…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Ziyang Gao , Yong Tian , Shih-Chi Lin , Junghua Lin

Longitudinal MRI analysis is crucial for predicting disease outcomes, particularly in chronic conditions like hepatocellular carcinoma (HCC), where early detection can significantly influence treatment strategies and patient prognosis. Yet,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Jakob Nolte , Maureen M. J. Guichelaar , Donald E. Bouman , Stephanie M. van den Berg , Maryam Amir Haeri