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We develop a stochastic algorithm for independent component analysis that incorporates multi-trial supervision, which is available in many scientific contexts. The method blends a proximal gradient-type algorithm in the space of invertible…

Machine Learning · Computer Science 2025-08-29 Ronak Mehta , Mateus Piovezan Otto , Noah Stanis , Azadeh Yazdan-Shahmorad , Zaid Harchaoui

Atom probe tomography (APT) is ideally suited to characterize and understand the interplay of chemical segregation and microstructure in modern multicomponent materials. Yet, the quantitative analysis typically relies on human expertise to…

We present a novel approach for adaptive, differentiable parameterization of large-scale random fields. If the approach is coupled with any gradient-based optimization algorithm, it can be applied to a variety of optimization problems,…

Machine Learning · Computer Science 2020-06-09 Maksim Elizarev , Andrei Mukhin , Aleksey Khlyupin

Amperometry is a commonly used electrochemical method for studying the process of exocytosis in real-time. Given the high precision of recording that amperometry procedures offer, the volume of data generated can span over several hundreds…

Subcellular Processes · Quantitative Biology 2023-02-07 Jeyashree Krishnan , Zeyu Lian , Pieter E. Oomen , Xiulan He , Soodabeh Majdi , Andreas Schuppert , Andrew Ewing

Complex phenomena can be better understood when broken down into a limited number of simpler "components". Linear statistical methods such as the principal component analysis and its variants are widely used across various fields of applied…

Data Analysis, Statistics and Probability · Physics 2025-01-13 Iacopo Tirelli , Miguel Alfonso Mendez , Andrea Ianiro , Stefano Discetti

Principal component analysis (PCA) has well-documented merits for data extraction and dimensionality reduction. PCA deals with a single dataset at a time, and it is challenged when it comes to analyzing multiple datasets. Yet in certain…

Machine Learning · Computer Science 2017-10-27 Gang Wang , Jia Chen , Georgios B. Giannakis

Numeric tabular datasets are the dominant data format in scientific practice, yet large language models lack native mechanisms for representing numeric datasets in a meaningful way across heterogeneous feature spaces. Existing approaches…

Machine Learning · Computer Science 2026-05-29 M. Ross Kunz , John Merickel , Keith Wilson

Independent component analysis (ICA) is a fundamental data processing technique to decompose the captured signals into as independent as possible components. Computing the contrast function, which serves as a measure of independence of…

Quantum Physics · Physics 2023-11-22 Xiao-Fan Xu , Cheng Xue , Zhao-Yun Chen , Yu-Chun Wu , Guo-Ping Guo

In this paper, we investigate the challenges to apply Statistical Static Timing Analysis (SSTA) in hierarchical design flow, where modules supplied by IP vendors are used to hide design details for IP protection and to reduce the complexity…

Hardware Architecture · Computer Science 2017-05-16 Bing Li , Ning Chen , Yang Xu , Ulf Schlichtmann

Post-clustering inference in single-cell RNA sequencing (scRNA-seq) analysis presents significant challenges in controlling Type I error during differential expression analysis. Data fission, a promising approach that aims to split data…

Methodology · Statistics 2026-03-23 Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum

High-dimensional astronomical data cubes provide a wealth of spectral and structural information that can be used to study astrophysical and chemical processes. The complexity and sheer size of these datasets pose significant challenges in…

Instrumentation and Methods for Astrophysics · Physics 2025-12-18 Haley N. Scolati , Ryan A. Loomis , Anthony J. Remijan , Kin Long Kelvin Lee

In order to improve the fault diagnosis capability of multivariate statistical methods, this article introduces a fault isolation framework based on structured sparsity modeling. The developed method relies on the reconstruction based…

Applications · Statistics 2020-12-22 Wei Chen , Jiusun Zeng , Xiaobin Xu , Shihua Luo , Chuanhou Gao

This article focuses on the robust principal component analysis (PCA) of high-dimensional data with elliptical distributions. We investigate the PCA of the sample spatial-sign covariance matrix in both nonsparse and sparse contexts,…

Methodology · Statistics 2025-07-08 Ping Zhao , Hongfei Wang , Long Feng

Unsupervised anomaly detection is a daunting task, as it relies solely on normality patterns from the training data to identify unseen anomalies during testing. Recent approaches have focused on leveraging domain-specific transformations or…

Machine Learning · Computer Science 2024-09-17 Hyuntae Kim , Changhee Lee

We introduce physics-informed multimodal autoencoders (PIMA) - a variational inference framework for discovering shared information in multimodal scientific datasets representative of high-throughput testing. Individual modalities are…

Machine Learning · Computer Science 2022-02-08 Nathaniel Trask , Carianne Martinez , Kookjin Lee , Brad Boyce

A time-frequency diagram is a commonly used visualization for observing the time-frequency distribution of radio signals and analyzing their time-varying patterns of communication states in radio monitoring and management. While it excels…

Signal Processing · Electrical Eng. & Systems 2022-10-03 Ying Zhao , Luhao Ge , Huixuan Xie , Genghuai Bai , Zhao Zhang , Qiang Wei , Yun Lin , Yuchao Liu , Fangfang Zhou

Discrete particle simulations are used to model segregation in granular mixtures of three different particle species in a horizontal rotating drum. Axial band formation is observed, with medium-size particles tending to be located between…

Soft Condensed Matter · Physics 2009-11-13 D. C. Rapaport

Deploying deep learning-based imaging tools across various clinical sites poses significant challenges due to inherent domain shifts and regulatory hurdles associated with site-specific fine-tuning. For histopathology, stain normalization…

We aim to analyze the relation between two random vectors that may potentially have both different number of attributes as well as realizations, and which may even not have a joint distribution. This problem arises in many practical…

Machine Learning · Statistics 2015-11-12 Hoang-Vu Nguyen , Jilles Vreeken

Materials with nanoscale phase separation are considered. These materials are formed by a mixture of several phases, so that inside one phase there exist nanosize inclusions of other phases, with random shapes and random spatial locations.…

Mesoscale and Nanoscale Physics · Physics 2014-03-31 V. I. Yukalov , E. P. Yukalova