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Computer-aided drug discovery is an essential component of modern drug development. Therein, deep learning has become an important tool for rapid screening of billions of molecules in silico for potential hits containing desired chemical…

In many applications, monitoring area under the ROC curve (AUC) in a sliding window over a data stream is a natural way of detecting changes in the system. The drawback is that computing AUC in a sliding window is expensive, especially if…

Machine Learning · Computer Science 2019-02-05 Nikolaj Tatti

In this paper we propose several adaptive gradient methods for stochastic optimization. Unlike AdaGrad-type of methods, our algorithms are based on Armijo-type line search and they simultaneously adapt to the unknown Lipschitz constant of…

We consider the offline change point detection and localization problem in the context of piecewise stationary networks, where the observable is a finite sequence of networks. We develop algorithms involving some suitably modified CUSUM…

Signal detection in environments with unknown signal bandwidth and time intervals is a fundamental problem in adversarial and spectrum-sharing scenarios. This paper addresses the problem of detecting signals occupying unknown degrees of…

Signal Processing · Electrical Eng. & Systems 2026-01-21 Ali Rasteh , Sundeep Rangan

This paper explores two recent methods for learning rate optimisation in stochastic gradient descent: D-Adaptation (arXiv:2301.07733) and probabilistic line search (arXiv:1502.02846). These approaches aim to alleviate the burden of…

Machine Learning · Computer Science 2023-08-08 Max McGuinness

We propose a computationally and statistically efficient procedure for segmenting univariate data under piecewise linearity. The proposed moving sum (MOSUM) methodology detects multiple change points where the underlying signal undergoes…

Methodology · Statistics 2023-08-25 Joonpyo Kim , Hee-Seok Oh , Haeran Cho

Coordinate descent (CD) algorithms have become the method of choice for solving a number of optimization problems in machine learning. They are particularly popular for training linear models, including linear support vector machine…

Machine Learning · Statistics 2014-01-16 Tobias Glasmachers , Ürün Dogan

We propose a descent subgradient algorithm for minimizing a real function, assumed to be locally Lipschitz, but not necessarily smooth or convex. To find an effective descent direction, the Goldstein subdifferential is approximated through…

Optimization and Control · Mathematics 2023-04-11 Morteza Maleknia , Majid Soleimani-damaneh

This work is devoted to the analysis of the performance of energy detection based spectrum sensing in the presence of enriched fading conditions which are distinct for the large number of multipath components and the lack of a dominant…

Information Theory · Computer Science 2016-12-30 Paschalis C. Sofotasios , Mulugeta K. Fikadu , Khuong Ho-Van , Mikko Valkama , George K. Karagiannidis

Optimizing machine learning algorithms that are used to solve the objective function has been of great interest. Several approaches to optimize common algorithms, such as gradient descent and stochastic gradient descent, were explored. One…

Machine Learning · Computer Science 2022-10-06 Hilal AlQuabeh , Farha AlBreiki , Dilshod Azizov

A efficient incremental learning algorithm for classification tasks, called NetLines, well adapted for both binary and real-valued input patterns is presented. It generates small compact feedforward neural networks with one hidden layer of…

Artificial Intelligence · Computer Science 2009-04-30 Juan-Manuel Torres-Moreno , Mirta B. Gordon

The receiver operating characteristic (ROC) curve is an important graphic tool for evaluating a test in a wide range of disciplines. While useful, an ROC curve can cross the chance line, either by having an S-shape or a hook at the extreme…

Methodology · Statistics 2024-07-02 Soutik Ghosal , Zhen Chen

This paper proposes an arc-search interior-point algorithm for the nonlinear constrained optimization problem. The proposed algorithm uses the second-order derivatives to construct a search arc that approaches the optimizer. Because the arc…

Optimization and Control · Mathematics 2025-06-13 Yaguang Yang

Anomaly Detection involves identifying deviations from normal data distributions and is critical in fields such as medical diagnostics and industrial defect detection. Traditional AD methods typically require the availability of normal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Alireza Salehi , Mohammadreza Salehi , Reshad Hosseini , Cees G. M. Snoek , Makoto Yamada , Mohammad Sabokrou

Many studies are devoted to the design of radiomic models for a prediction task. When no effective model is found, it is often difficult to know whether the radiomic features do not include information relevant to the task or because of…

Quantitative Methods · Quantitative Biology 2021-01-05 AS Dirand , F Frouin , I Buvat

When people evaluate the performance of a diagnostic test, it is important to control both True Positive Rate (TPR) and False Positive Rate (FPR). In the literature, most researchers propose the partial area under the ROC curve (pAUC) with…

Methodology · Statistics 2017-06-22 Hanfang Yang , Kun Lu , Xiang Lyu , Feifang Hu

The existing machine learning algorithms for minimizing the convex function over a closed convex set suffer from slow convergence because their learning rates must be determined before running them. This paper proposes two machine learning…

Optimization and Control · Mathematics 2019-09-02 Kazuhiro Hishinuma , Hideaki Iiduka

State-of-the-art object detection systems rely on an accurate set of region proposals. Several recent methods use a neural network architecture to hypothesize promising object locations. While these approaches are computationally efficient,…

Computer Vision and Pattern Recognition · Computer Science 2016-04-12 Yongxi Lu , Tara Javidi , Svetlana Lazebnik

When evaluating medical tests or biomarkers for disease classification, the area under the receiver-operating characteristic (ROC) curve is a widely used performance metric that does not require us to commit to a specific decision…

Methodology · Statistics 2013-10-21 Wanhua Su , Yan Yuan , Mu Zhu