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The Molecular Distance Geometry Problem (MDGP) is essential in structural biology, as it seeks to determine three-dimensional protein structures from partial interatomic distances. Its discretizable subclass (DMDGP) admits an exact…

Optimization and Control · Mathematics 2025-10-24 Leonardo D. Secchin , Wagner da Rocha , Mariana da Rosa , Leo Liberti , Carlile Lavor

The Distance Geometry Problem (DGP) seeks to find positions for a set of points in geometric space when some distances between pairs of these points are known. The so-called discretization assumptions allow to discretize the search space of…

Optimization and Control · Mathematics 2021-07-02 Moira MacNeil , Merve Bodur

Given an integer dimension K and a simple, undirected graph G with positive edge weights, the Distance Geometry Problem (DGP) aims to find a realization function mapping each vertex to a coordinate in K-dimensional space such that the…

Optimization and Control · Mathematics 2020-10-13 Moira MacNeil , Merve Bodur

It is well-known that by adding integrality constraints to the semidefinite programming (SDP) relaxation of the max-cut problem, the resulting integer semidefinite program is an exact formulation of the problem. In this paper we show…

Optimization and Control · Mathematics 2023-11-09 Frank de Meijer , Renata Sotirov

Given a weighted undirected graph $G=(V,E,d)$, the Molecular Distance Geometry Problem (MDGP) is that of finding a function $x:G\to \mathbb{R}^{3}$, where $||x(u)-x(v)||=d(u,v)$ for each $\{u,v\}\in E$. We show that under a few assumptions…

Biomolecules · Quantitative Biology 2007-05-23 Carlile Lavor , Leo Liberti , Nelson Maculan

Determining what to eat to satisfy nutritional requirements is one of the oldest optimization problems in operations research, yet existing formulations have two persistent limitations: continuous variables produce impractical fractional…

Artificial Intelligence · Computer Science 2026-05-15 Francisco Aguilera Moreno

In this paper, we present a novel method for solving multiobjective linear programming problems (MOLPP) that overcomes the need to calculate the optimal value of each objective function. This method is a follow-up to our previous work on…

Optimization and Control · Mathematics 2024-07-02 Mustapha Kaci , Sonia Radjef

A group of satellites, with either homogeneous or heterogeneous orbital characteristics and/or hardware specifications, can undertake a reconfiguration process due to variations in operations pertaining to Earth observation missions. This…

Optimization and Control · Mathematics 2024-09-06 Hang Woon Lee , Koki Ho

This paper proposes a novel primal heuristic for Mixed Integer Programs, by employing machine learning techniques. Mixed Integer Programming is a general technique for formulating combinatorial optimization problems. Inside a solver, primal…

Artificial Intelligence · Computer Science 2021-07-05 Yunzhuang Shen , Yuan Sun , Andrew Eberhard , Xiaodong Li

This paper presents a novel approach to the joint optimization of job scheduling and data allocation in grid computing environments. We formulate this joint optimization problem as a mixed integer quadratically constrained program. To…

While mixed-integer linear programming and convex programming solvers have advanced significantly over the past several decades, solution technologies for general mixed-integer nonlinear programs (MINLPs) have yet to reach the same level of…

Optimization and Control · Mathematics 2026-04-07 Danial Davarnia , Mohammadreza Kiaghadi , Junyuan Qiu

In this paper, we propose two exact distributed algorithms to solve mixed integer linear programming (MILP) problems with multiple agents where data privacy is important for the agents. A key challenge is that, because of the non-convex…

Optimization and Control · Mathematics 2022-05-03 Mohammad Javad Feizollahi

In this paper, we propose novel mixed-integer linear programming (MIP) formulations to model decision problems posed as influence diagrams. We also present a novel heuristic that can be employed to warm start the MIP solver, as well as…

Optimization and Control · Mathematics 2026-01-21 Helmi Hankimaa , Olli Herrala , Fabricio Oliveira , Jaan Tollander de Balsch

Maximum diversity problems arise in many practical settings from facility location to social networks, and constitute an important class of NP-hard problems in combinatorial optimization. There has been a growing interest in these problems…

Optimization and Control · Mathematics 2024-01-25 Francisco Parreño , Ramón Álvarez-Valdés , Rafael Martí

Integer programming (IP) has proven to be highly effective in solving many path-based optimization problems in robotics. However, the applications of IP are generally done in an ad-hoc, problem specific manner. In this work, after examined…

Robotics · Computer Science 2019-03-04 Shuai D. Han , Jingjin Yu

This paper addresses a mixed integer programming (MIP) formulation for the multi-item uncapacitated lot-sizing problem that is inspired from the trailer manufacturer. The proposed MIP model has been utilized to find out the optimum order…

Optimization and Control · Mathematics 2012-06-01 Maryam Mohammadi , Masine Md. Tap

Mixed-integer linear programming (MILP) is widely employed for modeling combinatorial optimization problems. In practice, similar MILP instances with only coefficient variations are routinely solved, and machine learning (ML) algorithms are…

Optimization and Control · Mathematics 2023-03-07 Qingyu Han , Linxin Yang , Qian Chen , Xiang Zhou , Dong Zhang , Akang Wang , Ruoyu Sun , Xiaodong Luo

Current state-of-the-art solvers for mixed-integer programming (MIP) problems are designed to perform well on a wide range of problems. However, for many real-world use cases, problem instances come from a narrow distribution. This has…

Optimization and Control · Mathematics 2022-02-15 Charly Robinson La Rocca , Emma Frejinger , Jean-François Cordeau

Graph theory has been a powerful tool in solving difficult and complex problems arising in all disciplines. In particular, graph matching is a classical problem in pattern analysis with enormous applications. Many graph problems have been…

Data Structures and Algorithms · Computer Science 2024-06-13 Bahram Alidaee , Haibo Wang , Hugh Sloan

Mixed-Integer Linear Programming (MILP) is a foundational tool for complex decision-making problems. However, the NP-hard nature of MILP presents a significant computational challenge, motivating the development of machine learning-based…

Optimization and Control · Mathematics 2026-03-03 Hongpei Li , Hui Yuan , Han Zhang , Jianghao Lin , Dongdong Ge , Mengdi Wang , Yinyu Ye
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