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Related papers: Metalic: Meta-Learning In-Context with Protein Lan…

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Parameter-Efficient Fine-Tuning (PEFT) is widely used for adapting Large Language Models (LLMs) for various tasks. Recently, there has been an increasing demand for fine-tuning a single LLM for multiple tasks because it requires overall…

Computation and Language · Computer Science 2026-05-15 Anjir Ahmed Chowdhury , Syed Zawad , Xiaolong Ma , Xu Dong , Feng Yan

Fine-tuning Pre-trained protein language models (PLMs) has emerged as a prominent strategy for enhancing downstream prediction tasks, often outperforming traditional supervised learning approaches. As a widely applied powerful technique in…

Computation and Language · Computer Science 2024-04-24 Yang Tan , Mingchen Li , Bingxin Zhou , Bozitao Zhong , Lirong Zheng , Pan Tan , Ziyi Zhou , Huiqun Yu , Guisheng Fan , Liang Hong

Meta-learning (ML) has emerged as a promising learning method under resource constraints such as few-shot learning. ML approaches typically propose a methodology to learn generalizable models. In this work-in-progress paper, we put the…

Machine Learning · Computer Science 2022-03-07 Aroof Aimen , Sahil Sidheekh , Vineet Madan , Narayanan C. Krishnan

Protein language models are trained primarily with masked language modeling (MLM), which predicts amino-acid identities at masked positions. We ask whether latent-space prediction can complement these token-level objectives under matched…

Machine Learning · Computer Science 2026-05-11 Dan Ofer , Dafna Shahaf , Michal Linial

Popular PEFT methods reduce trainable parameter count for fine-tuning by parameterizing new low-rank or sparse trainable weights in parallel to the frozen pre-trained weights $W$. However, these weights are trained from scratch, and there…

Machine Learning · Computer Science 2025-08-15 Suhas G Hegde , Shilpy Kaur , Aruna Tiwari

Recent work has shown that language models (LMs) trained with multi-task \textit{instructional learning} (MTIL) can solve diverse NLP tasks in zero- and few-shot settings with improved performance compared to prompt tuning. MTIL illustrates…

Computation and Language · Computer Science 2022-10-24 Budhaditya Deb , Guoqing Zheng , Ahmed Hassan Awadallah

Model agnostic meta-learning (MAML) is a popular state-of-the-art meta-learning algorithm that provides good weight initialization of a model given a variety of learning tasks. The model initialized by provided weight can be fine-tuned to…

Machine Learning · Computer Science 2021-06-11 Thanh Nguyen , Tung Luu , Trung Pham , Sanzhar Rakhimkul , Chang D. Yoo

Meta learning is a promising technique for solving few-shot fault prediction problems, which have attracted the attention of many researchers in recent years. Existing meta-learning methods for time series prediction, which predominantly…

Machine Learning · Computer Science 2023-11-07 Hai Su , Jiajun Hu , Songsen Yu

Neural networks require a large amount of annotated data to learn. Meta-learning algorithms propose a way to decrease the number of training samples to only a few. One of the most prominent optimization-based meta-learning algorithms is…

Machine Learning · Computer Science 2022-06-14 Kostiantyn Khabarlak

Recently, the remarkable capabilities of large language models (LLMs) have been illustrated across a variety of research domains such as natural language processing, computer vision, and molecular modeling. We extend this paradigm by…

Machine Learning · Computer Science 2023-09-04 Hongshuo Huang , Rishikesh Magar , Changwen Xu , Amir Barati Farimani

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Machine learning methods adapt the parameters of a model, constrained to lie in a given model class, by using a fixed learning procedure based on data or active observations. Adaptation is done on a per-task basis, and retraining is needed…

Machine Learning · Computer Science 2021-10-22 Osvaldo Simeone , Sangwoo Park , Joonhyuk Kang

A meta-model is trained on a distribution of similar tasks such that it learns an algorithm that can quickly adapt to a novel task with only a handful of labeled examples. Most of current meta-learning methods assume that the meta-training…

Machine Learning · Computer Science 2019-04-12 Minseop Park , Jungtaek Kim , Saehoon Kim , Yanbin Liu , Seungjin Choi

Currently, the growth of material data from experiments and simulations is expanding beyond processable amounts. This makes the development of new data-driven methods for the discovery of patterns among multiple lengthscales and time-scales…

Machine Learning · Computer Science 2020-10-14 Anke Stoll , Peter Benner

We propose an algorithm for meta-learning that is model-agnostic, in the sense that it is compatible with any model trained with gradient descent and applicable to a variety of different learning problems, including classification,…

Machine Learning · Computer Science 2017-07-19 Chelsea Finn , Pieter Abbeel , Sergey Levine

Protein-specific large language models (Protein LLMs) are revolutionizing protein science by enabling more efficient protein structure prediction, function annotation, and design. While existing surveys focus on specific aspects or…

Generalization beyond training data remains a central challenge in machine learning for biology. A common way to enhance generalization is self-supervised pre-training on large datasets. However, aiming to perform well on all possible…

Language models have emerged as powerful predictors of the viability of biological sequences. During training these models learn the rules of the grammar obeyed by sequences of amino acids or nucleotides. Once trained, these models can take…

Machine Learning · Computer Science 2025-04-25 Pranav Kantroo , Günter P. Wagner , Benjamin B. Machta

In recent years, Large Language Models (LLMs) have emerged as a prominent area of interest across various research domains, including Process Mining (PM). Current applications in PM have predominantly centered on prompt engineering…

Computation and Language · Computer Science 2025-09-04 Rafael Seidi Oyamada , Jari Peeperkorn , Jochen De Weerdt , Johannes De Smedt

Learning what to share between tasks has been a topic of great importance recently, as strategic sharing of knowledge has been shown to improve downstream task performance. This is particularly important for multilingual applications, as…

Computation and Language · Computer Science 2020-10-06 Farhad Nooralahzadeh , Giannis Bekoulis , Johannes Bjerva , Isabelle Augenstein
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