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Modern biological tools have made it possible to unequivocally demonstrate the deep relationship among species in terms of genes and basic molecular mechanisms. In addition, results from genetic, physical and physiological approaches…

Populations and Evolution · Quantitative Biology 2019-03-11 Jacques H. Daniel

This paper addresses the path selection problem from a known sender to the receiver. The proposed work shows path selection using genetic algorithm(GA)and simulated annealing (SA) approaches. In genetic algorithm approach, the multi point…

Neural and Evolutionary Computing · Computer Science 2016-09-08 T. R. Gopalakrishnan Nair , Kavitha Sooda

We consider an exactly solvable model of branching random walk with random selection, which describes the evolution of a population with $N$ individuals on the real line. At each time step, every individual reproduces independently, and its…

Probability · Mathematics 2018-10-09 Aser Cortines , Bastien Mallein

Population diversity is essential for avoiding premature convergence in Genetic Algorithms (GAs) and for the effective use of crossover. Yet the dynamics of how diversity emerges in populations are not well understood. We use rigorous…

Neural and Evolutionary Computing · Computer Science 2016-08-11 Duc-Cuong Dang , Tobias Friedrich , Timo Kötzing , Martin S. Krejca , Per Kristian Lehre , Pietro S. Oliveto , Dirk Sudholt , Andrew M. Sutton

In a wide variety of natural systems, closely-related microbial strains coexist stably, resulting in high levels of fine-scale biodiversity. However, the mechanisms that stabilize this coexistence are not fully understood. Spatial…

Populations and Evolution · Quantitative Biology 2023-03-29 Casey Barkan , Shenshen Wang

Down-sampling training data has long been shown to improve the generalization performance of a wide range of machine learning systems. Recently, down-sampling has proved effective in genetic programming (GP) runs that utilize the lexicase…

Neural and Evolutionary Computing · Computer Science 2022-06-01 Ryan Boldi , Thomas Helmuth , Lee Spector

Significant fraction (about 98.5% in humans, 24% in microbe Rickettsia prowazekii) of most animal genomes is non-coding DNA. Although recent studies established functions of its certain portions, it remains genomic dark matter. The paper…

Genomics · Quantitative Biology 2007-05-23 Mark Ya. Azbel

With neural networks having demonstrated their versatility and benefits, the need for their optimal performance is as prevalent as ever. A defining characteristic, hyperparameters, can greatly affect its performance. Thus engineers go…

Neural and Evolutionary Computing · Computer Science 2020-09-21 Keshav Ganapathy

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

Neural and Evolutionary Computing · Computer Science 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

A striking feature of our universe is its near criticality. The cosmological constant and weak hierarchy problems, as well as the metastability of the electroweak vacuum, can all be understood as problems of criticality. This suggests a…

High Energy Physics - Theory · Physics 2019-12-11 Justin Khoury , Onkar Parrikar

A magnitude limited sample of nearly 9000 early-type galaxies, in the redshift range 0.01 < z < 0.3, was selected from the Sloan Digital Sky Survey using morphological and spectral criteria. The Fundamental Plane relation in this sample is…

The current theory of evolution is almost the one Darwin and Wallace proposed two centuries ago and the following discoveries e.g., Mendelian genetics and neutral mutation theory have not made significant modifications. The current…

Populations and Evolution · Quantitative Biology 2023-09-14 Reza Rahmanzadeh

We focus on two aspects of cyclic orbit codes: invariants under equivalence and quasi-optimality. Regarding the first aspect, we establish a connection between the codewords of a cyclic orbit code and a certain linear set on the projective…

Information Theory · Computer Science 2025-01-08 Chiara Castello , Heide Gluesing-Luerssen , Olga Polverino , Ferdinando Zullo

In order to survive, reproduce and (in multicellular organisms) differentiate, cells must control the concentrations of the myriad different proteins that are encoded in the genome. The precision of this control is limited by the inevitable…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Aleksandra M. Walczak , William Bialek

It has long been hypothesized that operating close to the critical state is beneficial for natural and artificial systems. We test this hypothesis by evolving foraging agents controlled by neural networks that can change the system's…

Neural and Evolutionary Computing · Computer Science 2022-06-16 Jan Prosi , Sina Khajehabdollahi , Emmanouil Giannakakis , Georg Martius , Anna Levina

Intragenomic recombination (crossover) is a very important evolutionary mechanism. The crossover events are not evenly distributed along the natural chromosomes. Monte Carlo simulations revealed that frequency of recombinations decides…

Genomics · Quantitative Biology 2009-01-13 Wojciech Waga , Marta Zawierta , Jakub Kowalski , Stanislaw Cebrat

The application of Genetic Programming to the discovery of empirical laws is often impaired by the huge size of the search space, and consequently by the computer resources needed. In many cases, the extreme demand for memory and CPU is due…

Artificial Intelligence · Computer Science 2016-08-16 Alain Ratle , Michèle Sebag

Evolving systems, be it an antibody repertoire in the face of mutating pathogens or a microbial population exposed to varied antibiotics, constantly search for adaptive solutions in time-varying fitness landscapes. Generalists correspond to…

Biological Physics · Physics 2020-07-01 Shenshen Wang , Lei Dai

We have generalized our ``unified'' model of evolutionary ecology by taking into account the possible movements of the organisms from one ``patch'' to another within the same eco-system. We model the spatial extension of the eco-system…

Populations and Evolution · Quantitative Biology 2009-11-10 Dietrich Stauffer , Ambarish Kunwar , Debashish Chowdhury
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