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Related papers: Unlocking Real-Time Fluorescence Lifetime Imaging:…

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Fluorescence lifetime imaging (FLI) is an important technique for studying cellular environments and molecular interactions, but its real-time application is limited by slow data acquisition, which requires capturing large time-resolved…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Ismail Erbas , Vikas Pandey , Aporva Amarnath , Naigang Wang , Karthik Swaminathan , Stefan T. Radev , Xavier Intes

Fluorescence lifetime imaging (FLI) has been receiving increased attention in recent years as a powerful diagnostic technique in biological and medical research. However, existing FLI systems often suffer from a tradeoff between processing…

Image and Video Processing · Electrical Eng. & Systems 2025-11-10 Yang Lin , Paul Mos , Andrei Ardelean , Claudio Bruschini , Edoardo Charbon

High-throughput imaging workflows, such as Parallel Rapid Imaging with Spectroscopic Mapping (PRISM), generate data at rates that exceed conventional real-time processing capabilities. We present a scalable FPGA-based preprocessing pipeline…

Hardware Architecture · Computer Science 2025-11-26 Weichien Liao

Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Fluorescence Lifetime Imaging (FLI) is a critical molecular imaging modality that provides unique information about the tissue microenvironment, which is invaluable for biomedical applications. FLI operates by acquiring and analyzing photon…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Ismail Erbas , Vikas Pandey , Navid Ibtehaj Nizam , Nanxue Yuan , Amit Verma , Margarida Barosso , Xavier Intes

Compressive Macroscopic Fluorescence Lifetime Imaging (MFLI) is a novel technical implementation that enables monitoring multiple molecular interactions in macroscopic scale. Especially, we reported recently on the development of a…

Medical Physics · Physics 2018-02-23 Ruoyang Yao , Marien Ochoa , Xavier Intes , Pingkun Yan

We implement a specialized version of our SpeckleNN model for real-time speckle pattern classification in X-ray Single-Particle Imaging (SPI) using the SLAC Neural Network Library (SNL) on an FPGA. This hardware is optimized for inference…

Instrumentation and Detectors · Physics 2025-02-28 Abhilasha Dave , Cong Wang , James Russell , Ryan Herbst , Jana Thayer

This paper reported a bespoke adder-based deep learning network for time-domain fluorescence lifetime imaging (FLIM). By leveraging the l1-norm extraction method, we propose a 1-D Fluorescence Lifetime AdderNet (FLAN) without…

Signal Processing · Electrical Eng. & Systems 2022-09-13 Zhenya Zang , Dong Xiao , Quan Wang , Ziao Jiao , Chen Yu , David Day-Uei Li

Visual tracking is one of the most important application areas of computer vision. At present, most algorithms are mainly implemented on PCs, and it is difficult to ensure real-time performance when applied in the real scenario. In order to…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Ke Song , Chun Yuan , Peng Gao , Yunxu Sun

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Plenoptic cameras are receiving increasing attention in scientific and commercial applications because they capture the entire structure of light in a scene, enabling optical transforms (such as focusing) to be applied computationally after…

Image and Video Processing · Electrical Eng. & Systems 2020-10-16 Christopher Hahne , Andrew Lumsdaine , Amar Aggoun , Vladan Velisavljevic

We present a fast and accurate analytical method for fluorescence lifetime imaging microscopy (FLIM) using the extreme learning machine (ELM). We used extensive metrics to evaluate ELM and existing algorithms. First, we compared these…

Biological Physics · Physics 2022-03-28 Zhenya Zang , Dong Xiao , Quan Wang , Zinuo Li , Wujun Xie , Yu Chen , David Day Uei Li

Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Takashi Hato , Pierre C. Dagher , Evan L. Nichols , Cody J. Smith , Kenneth W. Dunn , Scott Howard

Correlation Plenoptic Imaging (CPI) is a novel technological imaging modality enabling to overcome drawbacks of standard plenoptic devices, while preserving their advantages. However, a major challenge in view of real-time application of…

Recent years have witnessed a rapid advancement in GPU technology, establishing it as a formidable high-performance parallel computing technology with superior floating-point computational capabilities compared to traditional CPUs. This…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-18 Xinyao Yi , Yuxin Qiao

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique in biomedical research that uses the fluorophore decay rate to provide additional contrast in fluorescence microscopy. However, at present, the calculation, analysis,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Cara Ravasio , Scott S. Howard

Photoluminesce (PL) spectroscopy offers excellent methods for mapping the PL decay on the nanosecond time scale. However, capturing maps of emission dynamics on the microsecond time scale can be highly time-consuming. We present a new…

Optics · Physics 2021-02-24 Jiri Junek , Karel Zidek

Optical continuous glucose monitoring (CGM) systems are emerging for personalized glucose management owing to their lower cost and prolonged durability compared to conventional electrochemical CGMs. Here, we report a computational CGM…

Efficient and real time segmentation of color images has a variety of importance in many fields of computer vision such as image compression, medical imaging, mapping and autonomous navigation. Being one of the most computationally…

Computer Vision and Pattern Recognition · Computer Science 2017-10-09 Roopal Nahar , Akanksha Baranwal , K. Madhava Krishna

Graph dynamic random walks (GDRWs) have recently emerged as a powerful paradigm for graph analytics and learning applications, including graph embedding and graph neural networks. Despite the fact that many existing studies optimize the…

Hardware Architecture · Computer Science 2023-04-24 Hongshi Tan , Xinyu Chen , Yao Chen , Bingsheng He , Weng-Fai Wong
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