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To interpret the genetic profile present in a patient sample, it is necessary to know which mutations have important roles in the development of the corresponding cancer type. Named entity recognition is a core step in the text mining…

Computation and Language · Computer Science 2021-06-16 Jiarun Cao , Elke M van Veen , Niels Peek , Andrew G Renehan , Sophia Ananiadou

Advance in medical imaging is an important part in deep learning research. One of the goals of computer vision is development of a holistic, comprehensive model which can identify tumors from histology slides obtained via biopsies. A major…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Vidit Gautam

The Cancer Genome Atlas (TCGA) provides researchers with clinicopathological data and genomic characterizations of various carcinomas. These data sets include expression microarrays for genes and microRNAs -- short, non-coding strands of…

Quantitative Methods · Quantitative Biology 2013-07-05 Siddharth G. Reddy , Weimin Xiao , Preethi H. Gunaratne

We utilized abundant transcriptomic data for the primary classes of brain cancers to study the feasibility of separating all of these diseases simultaneously based on molecular data alone. These signatures were based on a new method…

Quantitative Methods · Quantitative Biology 2013-08-05 Jaeyun Sung , Pan-Jun Kim , Shuyi Ma , Cory C. Funk , Andrew T. Magis , Yuliang Wang , Leroy Hood , Donald Geman , Nathan D. Price

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

Cancer development is associated with aberrant DNA methylation, including increased stochastic variability. Statistical tests for discovering cancer methylation biomarkers have focused on changes in mean methylation. To improve the power of…

Methodology · Statistics 2023-06-27 James Y. Dai , Heng Chen , Xiaoyu Wang , Wei Sun , Ying Huang , William M. Grady , Ziding Feng

The linking genotype to phenotype is the fundamental aim of modern genetics. We focus on study of links between gene expression data and phenotype data through integrative analysis. We propose three approaches. 1) The inherent complexity of…

Quantitative Methods · Quantitative Biology 2015-06-30 Min Xu

Classification is one of the major issues in Data Mining Research fields. The classification problems in medical area often classify medical dataset based on the result of medical diagnosis or description of medical treatment by the medical…

Artificial Intelligence · Computer Science 2013-01-09 N. Kalaiselvi , H. Hannah Inbarani

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

Early detection is crucial for successful cancer treatment and increasing survivability rates, particularly in the most common forms. Ten different cancers have been identified in most of these advances that effectively use CNNs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Hossein Molaeian , Kaveh Karamjani , Sina Teimouri , Saeed Roshani , Sobhan Roshani

We introduce a novel data-driven framework for the design of targeted gene panels for estimating exome-wide biomarkers in cancer immunotherapy. Our first goal is to develop a generative model for the profile of mutation across the exome,…

Genomics · Quantitative Biology 2022-02-04 Jacob R. Bradley , Timothy I. Cannings

Diagnosing Brain Tumor with the aid of Magnetic Resonance Imaging (MRI) has gained enormous prominence over the years, primarily in the field of medical science. Detection and/or partitioning of brain tumors solely with the aid of MR…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Md. Abu Bakr Siddique , Shadman Sakib , Mohammad Mahmudur Rahman Khan , Abyaz Kader Tanzeem , Madiha Chowdhury , Nowrin Yasmin

Brain cancer represents a major challenge in medical diagnostics, requisite precise and timely detection for effective treatment. Diagnosis initially relies on the proficiency of radiologists, which can cause difficulties and threats when…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Md. Arafat Alam Khandaker , Ziyan Shirin Raha , Salehin Bin Iqbal , M. F. Mridha , Jungpil Shin

Prostate cancer diagnosis through MR imaging have currently relied on radiologists' interpretation, whilst modern AI-based methods have been developed to detect clinically significant cancers independent of radiologists. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Xiangcen Wu , Yipei Wang , Qianye Yang , Natasha Thorley , Shonit Punwani , Veeru Kasivisvanathan , Ester Bonmati , Yipeng Hu

Many researches demonstrated that the DNA methylation, which occurs in the context of a CpG, has strong correlation with diseases, including cancer. There is a strong interest in analyzing the DNA methylation data to find how to distinguish…

Genomics · Quantitative Biology 2020-01-29 Hong Yu , Zhanyu Ma

Accurate and efficient classification of different types of cancer is critical for early detection and effective treatment. In this paper, we present the results of our experiments using the EfficientNet algorithm for classification of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Romario Sameh Samir

Linear discrimination, from the point of view of numerical linear algebra, can be treated as solving an ill-posed system of linear equations. In order to generate a solution that is robust in the presence of noise, these problems require…

Genomics · Quantitative Biology 2007-05-23 Erik Andries , Thomas Hagstrom , Susan R. Atlas , Cheryl Willman

Motivation: The consistent amount of different types of omics data requires novel methods of analysis and data integration. In this work we describe Regression2Net, a computational approach to analyse gene expression and methylation…

Computational Engineering, Finance, and Science · Computer Science 2015-07-06 Francesco Gadaleta , Kyrylo Bessonov

Breast cancer (BC) stands as one of the most common malignancies affecting women worldwide, necessitating advancements in diagnostic methodologies for better clinical outcomes. This article provides a comprehensive exploration of the…

Artificial Intelligence · Computer Science 2025-12-11 Samita Bai , Sidra Nasir , Rizwan Ahmed Khan , Alexandre Meyer , Hubert Konik